Internal Medicine
Study: Medication Review to Optimize and Potentially Reduce Psychotropic Drug Prescription in Institutionalized Dementia Patients
24 Jan, 2019 | 00:04h | UTCRelated: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
The Herd to the Rescue: How an Invisible Shield Can Keep us Healthy
23 Jan, 2019 | 14:25h | UTCThe herd to the rescue: How an invisible shield can keep us healthy – STAT (free)
Related: Case Report: Fatal Measles Case Highlights Importance of Herd Immunity in Protecting the Vulnerable (free case report and commentary)
A Review of Guidelines to Distinguish Between Gastric and Pulmonary Placement of Nasogastric Tubes
23 Jan, 2019 | 01:06h | UTC
New Canada’s Dietary Guidelines
23 Jan, 2019 | 01:25h | UTCCanada’s Dietary Guidelines – Government of Canada (free)
Homepage: Canada’s Food Guide (free resources)
Related Commentary on Twitter
New food guide: https://t.co/Yx15RSJ8ab My initial response, pretty solid! Like this image. And like that they are keeping message simple. @GovCanHealth #Canadasfoodguide. pic.twitter.com/Ab8Leqi19A
— Timothy Caulfield (@CaulfieldTim) January 22, 2019
Study: Safety of Men with Small and Medium Abdominal Aortic Aneurysms Under Surveillance
23 Jan, 2019 | 00:22h | UTCCommentaries: AAA Rupture Rate in England Supports Current Thresholds for Surveillance, Intervention—With Some Caveats – TCTMD (free) AND Safety of Abdominal Aortic Aneurysm Surveillance – American College of Cardiology (free)
Alex Nowbar’s weekly research reviews – 22 January 2019
23 Jan, 2019 | 00:20h | UTCAlex Nowbar’s weekly research reviews, 22 January 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events
22 Jan, 2019 | 22:18h | UTCAssociation of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Expert reaction to study looking at aspirin use in healthy people, and cardiovascular events and bleeding – Science Media Centre (free) AND Aspirin Modest at Best in Primary CV Prevention – MedPage Today (free registration required) AND When to take (or not take) aspirin to prevent heart trouble – CNN (free)
Related: Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (link to abstract and commentaries) AND Aspirin Did Not Prevent Deaths or Disability in Healthy Older Adults (free study and commentaries)
Canadian Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS)
22 Jan, 2019 | 18:02h | UTCRelated Guidelines: Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 (free) AND American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free) AND Irritable bowel syndrome in adults: diagnosis and management – National Institute for Health and Care Excellence (NICE) (free)
Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy
22 Jan, 2019 | 12:40h | UTCRelated Reviews: Sleep Apnea and Cardiovascular Disease: Lessons from Recent Trials and Need for Team Science – Circulation (free) AND Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences – Journal of the American College of Cardiology (free)
Perspective: Doing Things for No Reason in the Hospital
22 Jan, 2019 | 00:27h | UTCDoing things for no reason in the hospital – The BMJ Opinion (free)
“Many of the things we do as doctors continue simply because “that’s the way we’ve always done it,” says Abraar Karan”
“Opioids Don’t Work for Most People with Chronic Pain. So Why do We Still Prescribe Them?”
22 Jan, 2019 | 00:26h | UTCRelated study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)
See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Podcast: Sickle Cell Disease, Management & Complications
22 Jan, 2019 | 00:11h | UTC#136 Sickle Cell Disease, Management & Complications – The Curbsiders Internal Medicine Podcast (free)
Study: Duration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope
21 Jan, 2019 | 22:53h | UTCDuration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope – Circulation (link to abstract – $ for full-text)
Commentaries: How long do people need to be monitored after fainting? Study reveals best ways to catch life-threatening conditions – The Ottawa Hospital (free) AND 2 hours in the ER enough to rule out risky arrhythmias in most syncope patients – Cardiovascular Business (free)
Review: Low FODMAPs Diet for Patients with Irritable Bowel Syndrome
21 Jan, 2019 | 10:17h | UTC
Alcohol-related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study
21 Jan, 2019 | 10:08h | UTCAlcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study – Journal of Hepatology (free for a limited period)
New Treatment for Acquired Thrombotic Thrombocytopenic Purpura
21 Jan, 2019 | 10:12h | UTCCaplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: A New Drug for Patients with Thrombotic Thrombocytopenic Purpura – Transfusion News (free)
Systematic Review: Subacromial Decompression Surgery for Rotator Cuff Disease
20 Jan, 2019 | 17:14h | UTCSubacromial decompression surgery for rotator cuff disease – Cochrane Library (free)
Summary: Surgery for rotator cuff disease (free)
Related Studies: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement (free study and commentaries) AND Arthroscopic subacromial decompression for subacromial shoulder pain (free study and commentaries)
“The data in this review do not support the use of subacromial decompression in the treatment of rotator cuff disease manifest as painful shoulder impingement.”
Systematic Review: Adrenaline and Vasopressin for Cardiac Arrest
20 Jan, 2019 | 17:52h | UTCAdrenaline and vasopressin for cardiac arrest – Cochrane Library (free)
Summary: Adrenaline and vasopressin for cardiac arrest – Cochrane Library (free)
Related: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (link to abstract and commentaries) AND Opinion: Epinephrine Harms/Helps in Out of Hospital Cardiac Arrest (free commentaries) AND Review: The Role of Adrenaline in Cardiopulmonary Resuscitation (free)
Evidence‐based Guidelines for Screening of Diabetic Retinopathy
20 Jan, 2019 | 15:12h | UTCEvidence‐based Danish guidelines for screening of diabetic retinopathy – Acta Ophthalmologica (free)
“There is solid evidence to support a flexible, individualized screening regimen. In particular, it is possible to prolong screening intervals to 24–48 months for patients with no or mild nonproliferative diabetic retinopathy”.
Study: Remote, Non‐physician Led Hypertension Management Program
20 Jan, 2019 | 15:13h | UTCCommentary: Home-based hypertension program produces ‘striking’ results – Brigham and Women’s Hospital (free) AND At-home program helped 91% of patients control their BP in 7 weeks – Cardiovascular Business (free)
Autoimmune Hepatitis: Appraisal of Current Treatment Guidelines
20 Jan, 2019 | 14:40h | UTCAutoimmune hepatitis: Appraisal of current treatment guidelines – World Journal of Hepatology (free)
Related guidelines: 2019 Hellenic Association for the Study of the Liver Clinical Practice Guidelines: Autoimmune hepatitis 2019 – Annals of Gastroenterology (free) AND 2015 EASL Clinical Practice Guidelines: Autoimmune hepatitis – Journal of Hepatology (free PDF)
Systematic Review: Antidepressants do not Help Treat Depression in People Living with Dementia
20 Jan, 2019 | 13:47h | UTCAntidepressants do not help treat depression in people living with dementia – NIHR Signal (free)
Original Article: Antidepressants for treating depression in dementia – Cochrane Library (free)
Performance Improvement: Performing an Inadvertent Procedure
19 Jan, 2019 | 18:27h | UTCPerforming an Inadvertent Procedure – JAMA (free for a limited period)
Cohort Study: Common Conditions Associated with Hereditary Hemochromatosis Genetic Variants
18 Jan, 2019 | 01:03h | UTCCommentaries: Haemochromatosis: disorder that causes body to absorb too much iron from food may be major cause of disease – The Conversation (free) AND Haemochromatosis is linked to more disease than previously thought – The BMJ Opinion (free) AND Health impact of genetic ‘iron-overdose disease’ may have been underestimated – NHS News (free)
The EAT–Lancet Commission on Healthy Diets from Sustainable Food Systems
18 Jan, 2019 | 01:04h | UTCFood in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems – The Lancet (free articles – registration required)
Summary: EAT-Lancet Commission Brief for Everyone (free)
Commentaries: New Diet Guidelines to Benefit People and the Planet: More Greens for All, Less Meat for Some – The New York Times (10 articles per month are free) AND New ‘planetary health diet’ can save lives and the planet, major review suggests – CNN (free) AND A bit of meat, a lot of veg – the flexitarian diet to feed 10bn – BBC (free)
Related Commentary on Twitter
Feeding a population of 10 billion people by 2050 with a healthy & sustainable diet will be impossible without transforming eating habits, improving food production & reducing food waste—new @EATForum–@TheLancet Commission #EATLancet #foodcanfixit https://t.co/TsRQiyhA09 pic.twitter.com/v2KtYu9pdS
— The Lancet (@TheLancet) January 16, 2019


