Internal Medicine
[Abstract Only] Cohort Study: Use of Bisphosphonates and Risk of Osteonecrosis of the Jaw
10 Oct, 2019 | 09:14h | UTCUse of oral bisphosphonates and risk of hospital admission with osteonecrosis of the jaw: Large prospective cohort study in UK women – Bone (link to abstract – $ for full-text)
Commentary: Bisphosphonates and the Risk of Osteonecrosis of the Jaw – RheumNow (free)
[Abstract Only] Review: Colonoscopy Adverse Events
10 Oct, 2019 | 09:17h | UTCColonoscopy Adverse Events – NEJM Journal Watch (free)
Original Article: ASGE review of adverse events in colonoscopy – GIE Gastrointestinal Endoscopy (link to abstract – $ for full-text)
Meta-Analysis: Once-Weekly GLP-1 Receptor Agonist vs. SGLT-2 Inhibitors in Patients Inadequately Controlled with Oral Antidiabetic Drugs
10 Oct, 2019 | 09:13h | UTC
Physical Frailty: Clinical Practice Guidelines for Identification and Management
9 Oct, 2019 | 10:44h | UTC
Meta-Analysis: Benefits and Harms of Lower Blood Pressure Treatment Targets
9 Oct, 2019 | 10:43h | UTCCommentary: BP lowering in 130-140 mmHg range offers no benefits, some risk – Univadis (free registration required)
[Abstract Only] Observational Study Suggests that Guidelines from the Canadian Cardiovascular Society, ACC/AHA, and NICE Provide Better Guidance for Statin Use than Other Guidelines
9 Oct, 2019 | 10:37h | UTCStatin Use in Primary Prevention of Atherosclerotic Cardiovascular Disease According to 5 Major Guidelines for Sensitivity, Specificity, and Number Needed to Treat – JAMA Cardiology (link to abstract – $ for full-text)
Commentary: Statin Use in Primary Prevention of ASCVD According to 5 Guidelines – American College of Cardiology (free)
Meta-Analysis: Age at Natural Menopause and Risk of Incident Cardiovascular Disease
8 Oct, 2019 | 10:11h | UTCCommentaries: Early menopause and risk of cardiovascular disease: an issue for young women – The Lancet Public Health (free) AND Early menopause predictor of heart disease – University of Queensland (free)
[Abstract Only] Cohort Studies: Effects of Sugary Beverages and Artificially Sweetened Beverages on the Risk of Type 2 Diabetes
8 Oct, 2019 | 10:10h | UTCChanges in Consumption of Sugary Beverages and Artificially Sweetened Beverages and Subsequent Risk of Type 2 Diabetes: Results From Three Large Prospective U.S. Cohorts of Women and Men – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Drinking more sugary beverages of any type may increase type 2 diabetes risk – Harvard T.H. Chan School of Public Health (free) AND Even naturally sweet drinks may increase diabetes risk – Medical News Today (free)
Expert Statement on the ICU Management of Thrombotic Thrombocytopenic Purpura
8 Oct, 2019 | 10:09h | UTCRelated Guidelines: Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies – British Journal of Haematology (free) AND Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan – International Journal of Hematology (free) AND Consensus opinion on diagnosis and management of thrombotic microangiopathy in Australia and New Zealand – Nephrology (free)
ESC Consensus Report: Cardiovascular Care of Patients with Stroke and High Risk of Stroke
8 Oct, 2019 | 10:05h | UTC
Podcast: In-Flight Emergencies
8 Oct, 2019 | 10:06h | UTCIn-Flight Emergencies REBOOT with Angelica Zen MD – The Curbsiders Internal Medicine Podcast (free)
Related: In-Flight Medical Emergencies: A Review – JAMA (free)
Consensus Recommendations for Management of Patients with Type 2 Diabetes Mellitus and Cardiovascular Diseases
8 Oct, 2019 | 09:38h | UTCRelated: 2019 ESC Guidelines on Diabetes, Pre-diabetes, and Cardiovascular Diseases (free)
British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease
7 Oct, 2019 | 06:10h | UTCRelated Guidelines: Evidence-based clinical practice guidelines for inflammatory bowel disease – Journal of Gastroenterology (free) AND Ulcerative colitis: management – National Institute for Health and Care Excellence (free) AND ACG Clinical Guideline: Ulcerative Colitis in Adults – American Journal of Gastroenterology (free) AND AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology (free) AND Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie (free) AND Management of Paediatric Ulcerative Colitis (free) AND Crohn’s disease: management – National Institute for Health and Care Excellence (free) AND ACG Clinical Guideline: Management of Crohn’s Disease in Adults – The American Journal of Gastroenterology (free) AND Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn’s Disease – Journal of the Canadian Association of Gastroenterology (free)
[Abstract Only] Randomized Trial: Low Dose Azithromycin During Acute COPD Exacerbations Requiring Hospitalization
7 Oct, 2019 | 05:57h | UTCAzithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Impact of Azithromycin Studied in Acute Exacerbation of COPD – Physician’s Briefing (free) AND Low-Dose Azithromycin May Improve COPD Exacerbation Outcomes – MedPage Today (free registration required)
Source: EvidenceAlerts
Randomized Trial: Penicillin V Four Times Daily for Five Days vs. Three Times Daily for 10 days for Pharyngotonsillitis Caused by Group A Streptococci
7 Oct, 2019 | 05:59h | UTC
Related Commentary on Twitter
NEW 🔥 @bmj_latest
Penicillin V four times daily for five days versus three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci: 🇸🇪 randomised controlled, open label, non-inferiority study. #IDTwitter #IDuptodate https://t.co/djhOIvAbPc— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) October 5, 2019
Guideline Synopsis: Primary Prevention of Cardiovascular Disease
7 Oct, 2019 | 05:54h | UTCPrimary Prevention of Cardiovascular Disease – JAMA (free for a limited period)
Original Guideline: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free guideline and resources)
Related Summaries: The ABCs of Primary Cardiovascular Prevention: 2019 Update – American College of Cardiology (free) AND Key Points From the 2019 ACC/AHA Guidelines on the Primary Prevention of Cardiovascular Disease – American College of Cardiology (free)
50 Pieces of Advice to Young Psychiatrists from a Very Old One
7 Oct, 2019 | 05:49h | UTCAdvice to Young Psychiatrists From a Very Old One – Psychiatric Times (free)
Study: Consuming More than 14.0 Drinks per Week Associated with Lower Cognitive Scores Among Older Individuals
7 Oct, 2019 | 00:54h | UTCCommentaries: Alcohol and dementia risk: A complex relationship – Medical News Today (free) AND Alcohol Consumption May Increase Dementia Risk in Older Adults – Psychiatric News Alert (free) AND Expert reaction to study looking at alcohol and risk of dementia and cognitive decline – Science Media Centre (free)
Supplement: Obstructive Sleep Apnea
4 Oct, 2019 | 07:54h | UTC– Homepage (free)
– Introduction—Obstructive sleep apnea: A wake-up call for better outcomes (free)
– Obstructive sleep apnea basics (free)
– Sleep apnea and the heart (free)
– Beyond heart health: Consequences of obstructive sleep apnea (free)
– Positive airway pressure: Making an impact on sleep apnea (free)
– Alternative interventions for obstructive sleep apnea (free)
Perspective: Blame Rising Cancer Overdiagnosis on ‘Irrational Exuberance’ for Early Detection
4 Oct, 2019 | 08:08h | UTCBlame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free)
Related: What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)
Review: Medical Treatment of Primary Aldosteronism
4 Oct, 2019 | 08:04h | UTCMedical treatment of primary aldosteronism – European Journal of Endocrinology (free)
A Comprehensive Algorithm for Management of Neuropathic Pain
4 Oct, 2019 | 08:06h | UTCA Comprehensive Algorithm for Management of Neuropathic Pain – Pain Medicine (free)
Related Guidelines: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free) AND Pharmacologic management of chronic neuropathic pain: Review of the Canadian Pain Society consensus statement – Canadian Family Physician (free) AND Executive summary of the Clinical Guidelines of Pharmacotherapy for Neuropathic Pain: second edition by the Japanese Society of Pain Clinicians – Journal of Anesthesia (free)
2019 Update in Perioperative Cardiovascular Medicine
4 Oct, 2019 | 07:37h | UTC2019 Update in perioperative cardiovascular medicine – Cleveland Clinic Journal of Medicine (free)
Case Report: Perioperative Management in a Patient with Panhypopituitarism – Evidence Based Approach
4 Oct, 2019 | 07:15h | UTC
BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy
3 Oct, 2019 | 07:45h | UTCEditorial: Personalised and risk based cancer screening (free)
Related Study: Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study – The BMJ (free)
Commentaries: Guideline Moves Away from Colorectal Cancer Screening for Some – NEJM Journal Watch (free) AND First Guideline to Say Colon Cancer Screening Is Not for All – Medscape (free registration required)
Related Guidelines: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)
Related Commentary on Twitter
Routine testing for bowel cancer should not be recommended for everyone aged 50-79 years because, for those at very low risk, the benefit is small and uncertain and there are potential harms, finds new #RapidRecs guideline https://t.co/68xTtEDHxQ
— The BMJ (@bmj_latest) October 3, 2019


