Internal Medicine
U.S. Prevalence of Underlying Health Conditions Among Patients with COVID-19
1 Apr, 2020 | 05:45h | UTCCommentaries: More than 70% of Americans hospitalized with COVID-19 had at least 1 underlying health condition, the CDC says — here’s the breakdown – Business Insider AND People With Underlying Health Conditions Are At Risk Of More Severe COVID-19, Says New CDC Report – Forbes AND Who’s Sickest From COVID-19? These Conditions Tied To Increased Risk – NPR
COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features
1 Apr, 2020 | 05:40h | UTCCOVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features – Radiology
Expert Consensus: Management of Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
31 Mar, 2020 | 04:57h | UTC
COVID-19: Risks Related to the Use of Hydroxychloroquine
31 Mar, 2020 | 04:48h | UTC- Ventricular Arrhythmia Risk Due to Hydroxychloroquine-Azithromycin Treatment For COVID-19 – American College of Cardiology
- A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19 – Annals of Internal Medicine
Study: SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19
31 Mar, 2020 | 04:40h | UTC
[Preprint] COVID-19: Hydroxychloroquine Beneficial in Small Trial
31 Mar, 2020 | 04:51h | UTC
Ethical Considerations in the Allocation of Critical Care Resources When Capacity is Overwhelmed
31 Mar, 2020 | 04:37h | UTC
Review: Oral Step-Down Therapy for the Treatment of Infective Endocarditis
31 Mar, 2020 | 04:33h | UTCEvaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review – JAMA Internal Medicine (free for a limited period)
Author Interview: Evaluation of the Shift From Intravenous Antibiotics to Oral Step-Down Therapy for Infective Endocarditis (free)
ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease
31 Mar, 2020 | 04:29h | UTC
ISCHEMIA Trial: Health-Status Outcomes with Initial Invasive vs. Conservative Care in Stable Coronary Disease
31 Mar, 2020 | 04:26h | UTCCommentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology AND NIH-funded studies show stents and surgery no better than medication, lifestyle changes at reducing cardiac events – NIH News Releases
ISCHEMIA Trial: Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease
31 Mar, 2020 | 04:31h | UTC
ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease
31 Mar, 2020 | 04:28h | UTCCommentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology AND NIH-funded studies show stents and surgery no better than medication, lifestyle changes at reducing cardiac events – NIH News Releases
JAMA Guideline Synopsis: Management of Critically Ill Adults With COVID-19
30 Mar, 2020 | 02:17h | UTCManagement of Critically Ill Adults With COVID-19 – JAMA
Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19
Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine
Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm
Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence
NICE Guideline: Venous Thromboembolic Diseases
30 Mar, 2020 | 02:27h | UTC
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
30 Mar, 2020 | 02:12h | UTCTreatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA
Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges
Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI
See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration
N95 Re-Use Instructions
30 Mar, 2020 | 02:06h | UTCN95 Re-Use Instructions – SAGES
Related: Conserving Supply of Personal Protective Equipment—A Call for Ideas – JAMA AND N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine
COVID-19: Controversies on the Use of Face Masks
30 Mar, 2020 | 02:10h | UTC- Would everyone wearing face masks help us slow the pandemic? – Science
- Not wearing masks to protect against coronavirus is a ‘big mistake,’ top Chinese scientist says – Science
- More Americans Should Probably Wear Masks for Protection – The New York Times
- Experts say face masks can help slow COVID-19, despite previous claims – New York Post
- Coronavirus: Chinese scientist advises people in Europe, US to wear face masks in public – South China Morning Post
Related Guidance: WHO Recommendations on when and how to use masks – World Health Organization AND Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention
Primary Care & Coronavirus (COVID 19): Key Guidance, Information and Support
30 Mar, 2020 | 01:45h | UTCPrimary care & Coronavirus (COVID 19): key guidance, information and support – Medium
Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care – The BMJ
Related Commentary on Twitter
I've written a blog for primary care on #coronavirus:
🗣️ Preparing, comms, diagnosis
📞 Remote consulting
😷 PPE
💊 Coding/meds
👨👨👦👦 Pt resources
🏥 Clinical advice for diff groups/ways of working
🌍 General resources
🛏️ Professional support— Dipesh Gopal (@DipeshGopal) March 28, 2020
A War on Two Fronts: Cancer Care in the Time of COVID-19
30 Mar, 2020 | 01:51h | UTCA War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine
Related Guidelines: COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence AND Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network
Video: Coronavirus (COVID-19) Update: Fairly Rationing ICU Care
30 Mar, 2020 | 01:30h | UTCCoronavirus (COVID-19) Update: Fairly Rationing ICU Care – JAMA
COVID-19 and Renin-Angiotensin System Blockers
30 Mar, 2020 | 02:00h | UTCRenin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers – Hypertension AND Commentary: COVID-19 alert: Heart and kidney patients should keep taking their medicines – University of Miami Miller School of Medicine
Related Guidelines: HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use AND Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology
The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19)
30 Mar, 2020 | 01:33h | UTC
Review: Potential Effects of Coronaviruses on the Cardiovascular System
30 Mar, 2020 | 01:41h | UTCPotential Effects of Coronaviruses on the Cardiovascular System: A Review – JAMA Cardiology
Editorial: Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality
Related Articles: Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China – JAMA Cardiology AND Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology
Commentary: A Heart Attack? No, It Was the Coronavirus – The New York Times
#ACC20 – [Abstract only] Randomized Trial: Rivaroxaban or Enoxaparin in Nonmajor Orthopedic Surgery
30 Mar, 2020 | 01:20h | UTCRivaroxaban or Enoxaparin in Nonmajor Orthopedic Surgery – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: PRONOMOS: Rivaroxaban Better Than Enoxaparin in Preventing VTE After Nonmajor Orthopedic Surgery – American College of Cardiology (free) AND PROphylaxis in NON-Major Orthopedic Surgery – PRONOMOS – American College of Cardiology (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
#ACC20 – [Abstract Only] Randomized Trial: Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
30 Mar, 2020 | 01:13h | UTCAnticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Antithrombotic Therapy After Transcatheter Aortic Valve Implantation in Patients With a Long-Term Indication for Oral Anticoagulation – POPular TAVI – American College of Cardiology (free)AND A-fib Patients Undergoing TAVR Do Better With OAC Alone: POPular TAVI – TCTMD (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)