Internal Medicine
Systematic Review: Topical and Device‐based Treatments for Fungal Infections of the Toenails
26 Jan, 2020 | 22:39h | UTCTopical and device‐based treatments for fungal infections of the toenails – Cochrane Library (free)
Summary: Are topical and device-based treatments effective in people with fungal infections of the toenails? – Cochrane Library (free)
Meta-Analysis: Antibiotic Prophylaxis to Prevent Spontaneous Bacterial Peritonitis in People with Liver Cirrhosis
26 Jan, 2020 | 22:37h | UTCAntibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis – Cochrane Library (free)
Summary: Use of antibiotics to prevent spontaneous bacterial peritonitis in people with advanced liver disease – Cochrane Library (free)
Meta-Analysis: Treatment for Ascites in Adults with Decompensated Liver Cirrhosis
26 Jan, 2020 | 22:36h | UTCTreatment for ascites in adults with decompensated liver cirrhosis: a network meta‐analysis – Cochrane Library (free)
Summary: Treatments for ascites in people with advanced liver disease – Cochrane Library (free)
Over-Testing for Suspected Pulmonary Embolism in Emergency Departments: The Continuing Epidemic
24 Jan, 2020 | 08:15h | UTCCommentary: Overuse of CT Scans for Suspected Pulmonary Embolism Persists – TCTMD (free)
Systematic Review: Predictive Value of Traditional Risk Factors for Cardiovascular Disease in Older People
24 Jan, 2020 | 08:02h | UTC
Update on the Diagnosis and Management of Exocrine Pancreatic Insufficiency
24 Jan, 2020 | 07:57h | UTCUpdate on the diagnosis and management of exocrine pancreatic insufficiency – F1000Research (free)
ESC Position Paper: Update on Cardiovascular Prevention in Clinical Practice
23 Jan, 2020 | 09:55h | UTC
CDC: Novel Coronavirus Situation Summary and Updates
23 Jan, 2020 | 09:49h | UTC2019 Novel Coronavirus (2019-nCoV), Wuhan, China – Centers for Disease Control and Prevention (free)
Report 2: Estimating the potential total number of novel Coronavirus cases in Wuhan City, China – Imperial College London (free)
See also: WHO Director-General’s statement on IHR Emergency Committee on Novel Coronavirus – World Health Organization (free) AND Wuhan, China Goes On Lockdown; WHO Postpones Decision On Public Health Emergency Over Virus Outbreak – Health Policy Watch (free) AND China locks down city of 11 million at epicenter of virus outbreak – Reuters (free) AND Coronavirus Live Updates: More Than 570 Infected, as City Is Put on Lockdown – The New York Times (10 articles per month are free) AND Newly Identified Coronavirus Has Killed 17 People, Chinese Health Officials Say – NPR (free) AND Editorial: Stop the Wuhan virus – Nature (free)
ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated”
22 Jan, 2020 | 09:44h | UTCCommentary: Risk of kidney injury in contrast CT imaging overstated, experts say – UPI (free)
Related: Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
Position Paper: Diagnosis and Risk Stratification of Chest Pain Patients in the Emergency Department
22 Jan, 2020 | 09:43h | UTCDiagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association – European Heart Journal: Acute Cardiovascular Care (free for a limited period)
WHO Q & A – E-cigarettes: How Risky Are They?
22 Jan, 2020 | 09:39h | UTCE-cigarettes: how risky are they? – World Health Organization (free)
Related Commentary on Twitter (Thread – Click for More)
E-cigarettes are harmful to health and are not safe.
They are particularly risky when used by adolescents. Nicotine is highly addictive & young people’s brains develop up to their mid-twenties. Exposure to nicotine can have long-lasting, damaging effects.https://t.co/S8ZHoux45e pic.twitter.com/mkx0d5GCpW— World Health Organization (WHO) (@WHO) January 21, 2020
[Abstract Only] Meta-Analysis: Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics May be Safe
22 Jan, 2020 | 09:31h | UTCTreatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum (link to abstract – $ for full-text)
Related: Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis (randomized trials on the subject)
Randomized Trial: Hydroxyethyl Starch vs. Saline for Volume Replacement Therapy in High-Risk Patients Undergoing Major Abdominal Surgery
22 Jan, 2020 | 09:36h | UTCEffect of Hydroxyethyl Starch vs Saline for Volume Replacement Therapy on Death or Postoperative Complications Among High-Risk Patients Undergoing Major Abdominal Surgery: The FLASH Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Hydroxyethyl Starch for Fluid Replacement Therapy in High-Risk Surgical Patients: Context and Caution (free for a limited period)
Related Cochrane Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People (free)
Related Commentary on Twitter
FLASH trial published today in @JAMA_current, comparing saline versus HES in high risk surgical patients.https://t.co/5xet1jOtEA
Our accompanying editorial, which hopefully helps to contextualizing the results can be found at:https://t.co/Ebl9ieG5Sp— Fernando Zampieri (@f_g_zampieri) January 21, 2020
Managing Clinical Uncertainty: A Teachable Moment
22 Jan, 2020 | 09:33h | UTCManaging Clinical Uncertainty: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
[Abstract Only] Systematic Review: No Benefit from Flexible Titration Above Minimum Licensed Dose in Prescribing Antidepressants for Major Depression
22 Jan, 2020 | 09:27h | UTCNo benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review – Acta Psychiatrica Scandinavica (link to abstract – $ for full-text)
Related Meta-analysis: Optimal Dose of Antidepressants in Major Depression – The Lancet Psychiatry (free study and commentaries)
[Abstract Only] Randomized Trial: Effectiveness of Mirtazapine as Add-on to Paroxetine vs. Paroxetine or Mirtazapine Monotherapy in Patients with Depression with Early Non-response to Paroxetine
22 Jan, 2020 | 09:08h | UTCEffectiveness of mirtazapine as add-on to paroxetine v. paroxetine or mirtazapine monotherapy in patients with major depressive disorder with early non-response to paroxetine: a two-phase, multicentre, randomized, double-blind clinical trial – Psychological Medicine (link to abstract – $ for full-text)
Palliative Sedation: A Safety Net for the Relief of Refractory and Intolerable Symptoms at the End of Life
22 Jan, 2020 | 09:06h | UTC
Pain and Delirium: Mechanisms, Assessment, and Management
22 Jan, 2020 | 09:04h | UTCPain and delirium: mechanisms, assessment, and management – European Geriatric Management (free)
Podcast: Lipids Update and Cardiovascular Risk Reduction
21 Jan, 2020 | 03:10h | UTCSee also: Episode List
Document to Defeat Malpractice Suits: 10 Tips for Hospitalists
21 Jan, 2020 | 03:08h | UTC
Screening for Colon Cancer in Older Adults: Risks, Benefits, and When to Stop
21 Jan, 2020 | 03:02h | UTC
Editorial – Back to Basics: 10 Facts Every Person Should Know About Back Pain
21 Jan, 2020 | 03:04h | UTCCommentary: Myths may worsen low back pain and promote ineffective treatments – Reuters (free)
Study – Troponin Testing and Coronary Syndrome in Geriatric Patients with Nonspecific Complaints: Are We Overtesting?
21 Jan, 2020 | 02:58h | UTCCommentaries: Study questions routine troponin testing for ACS in geriatric patients with NSCs – Society for Academic Emergency Medicine (free) AND This Old Heart of Mine and Troponin Testing – The Skeptics Guide to EM (free)
Cohort Study: Premature Menopause Linked to Increased Risk of Development of Chronic Conditions and Multimorbidity
21 Jan, 2020 | 01:30h | UTCCommentary: Premature menopause increases the risk of multiple health problems in your 60s – European Society of Human Reproduction and Embryology (free)
Meta-Analysis of Randomized Trials: Effects of Metformin on Blood Lipid Profiles in Nondiabetic Adults
21 Jan, 2020 | 01:09h | UTC