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Internal Medicine

Commentary on the New IDSA’s COVID-19 Treatment Guidelines

14 Apr, 2020 | 02:49h | UTC

IDSA’s COVID-19 Treatment Guidelines Highlight Difficulty of “Don’t Just Do Something, Stand There” – HIV and ID Observations Blog

See Original Guideline: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19

 


Study Validates Loss of Smell and Taste as Symptoms of Covid-19

14 Apr, 2020 | 02:57h | UTC

Association of chemosensory dysfunction and Covid‐19 in patients presenting with influenza‐like symptoms – International Forum of Allergy & Rhinology

Commentary: Loss of smell and taste validated as COVID-19 symptoms in patients with high recovery rate – University of California

 


Face Masks Against COVID-19: An Evidence Review

14 Apr, 2020 | 02:52h | UTC

Face Masks Against COVID-19: An Evidence Review – Preprints

Related Analysis: Face Masks for the Public During the Covid-19 Crisis

 


Review: Management of Inflammatory Bowel Disease Patients in the COVID-19 Pandemic Era

14 Apr, 2020 | 02:55h | UTC

Management of inflammatory bowel disease patients in the COVID-19 pandemic era: a Brazilian tertiary referral center guidance – Clinics

Related: AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary – Gastroenterology AND Management of Patients with Crohn’s Disease and Ulcerative Colitis During the COVID-19 Pandemic: Results of an International Meeting – Gastroenterology

 


Richard Lehman’s Covid-19 Reviews

14 Apr, 2020 | 02:46h | UTC

Richard Lehman’s covid-19 reviews—13 April 2020 – The BMJ Opinion

“In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19.”

 


WHO Scientific Brief: BCG vaccination and COVID-19

14 Apr, 2020 | 02:47h | UTC

Bacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization

Related Opinion: BCG Against Coronavirus: Less Hype and More Evidence, Please

“There is no evidence that the Bacille Calmette-Guérin vaccine (BCG) protects people against infection with COVID-19 virus.”

 


AHA Statement: Management of Stable Coronary Artery Disease in Patients with Type 2 Diabetes

14 Apr, 2020 | 02:33h | UTC

Clinical Management of Stable Coronary Artery Disease in Patients With Type 2 Diabetes Mellitus: A Scientific Statement From the American Heart Association – Circulation

News Release: People with type 2 diabetes and heart disease may benefit from newer therapies – American Heart Association

 


IDSA Guidelines on the Treatment and Management of Patients with COVID-19 Infection

13 Apr, 2020 | 00:27h | UTC

Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection

 

Related Commentary on Twitter

 


Compassionate Use of Remdesivir for Patients with Severe Covid-19

13 Apr, 2020 | 00:23h | UTC

Compassionate Use of Remdesivir for Patients with Severe Covid-19 – New England Journal of Medicine

Commentaries: PulmCrit – Eleven reasons the NEJM paper on remdesivir reveals nothing AND Expert reaction to a study about compassionate use of remdesivir for patients with severe COVID-19 – Science Media Centre AND What Do the New Remdesivir Data Mean? – Science Translational Medicine

 


Study: Neurologic Manifestations Common in Hospitalized Patients with Covid-19

13 Apr, 2020 | 00:25h | UTC

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China – JAMA Neurology

Editorial: The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines

Commentaries: 40% of people with severe COVID-19 experience neurological complications – UPI AND AND Expert reaction to paper on neurological manifestations of patients hospitalised with COVID-19 in Wuhan, China – Science Media Centre

Related: Preparing a neurology department for SARS-CoV-2 (COVID-19): Early experiences at Columbia University Irving Medical Center and the New York Presbyterian Hospital in New York City – Neurology

 


Possible Algorithm to Empiric Anticoagulation in COVID-19 Based on D-Dimer

13 Apr, 2020 | 00:20h | UTC

D-dimer cutoffs to predict thrombosis in COVID-19 – PulmCrit

Note: this link is not an endorsement of the algorithm.

Related Guidance: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis

 


Incidence of Thrombotic Complications in Critically ill ICU Patients with COVID-19

13 Apr, 2020 | 00:22h | UTC

Incidence of thrombotic complications in critically ill ICU patients with COVID-19 – Thrombosis Research

Related Observational Studies: Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis AND Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis

 


Implementation Guide: Optimizing Medication Management during the COVID-19 Pandemic

13 Apr, 2020 | 00:18h | UTC

Optimizing Medication Management during the COVID-19 Pandemic: Implementation Guide for Post-Acute and Long-Term Care – University of Maryland School of Pharmacy

 

Related Commentary on Twitter

 


Studies: Obesity Increases the Risk of Complications in Patients with Covid-19

13 Apr, 2020 | 00:14h | UTC

1 – High prevalence of obesity in severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) requiring invasive mechanical ventilation – Obesity

2 – Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission – Clinical Infectious Diseases AND Commentary: In New York, obesity appears to raise COVID-19 risk – CIDRAP

 


Study: Antibody Tests Reveal 14% are Immune to Covid-19 in German Town

13 Apr, 2020 | 00:10h | UTC

The original report can be found here (in German)

 


Studies: Diabetes Increases the Risk of Complications in Patients with Covid-19

13 Apr, 2020 | 00:12h | UTC

1 – Prevalence and impact of diabetes among people infected with SARS-CoV-2 – Journal of Endocrinological Investigation AND Commentary: Diabetes Could Increase Severity of COVID-19, Including Risk of ICU Admission and Death – MedicalResearch.com

2 – Evidence Reviews: Diabetes and risks from COVID-19 – CEBM University of Oxford AND Managing diabetes during the COVID-19 pandemic – CEBM University of Oxford

 


[Preprint] Factors Associated with Worse Outcomes Among 4,103 Patients with COVID-19 in New York City

13 Apr, 2020 | 00:09h | UTC

Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City – medRxiv

 


Updated Guidance on Personal Protective Equipment (PPE) for Clinicians

13 Apr, 2020 | 00:02h | UTC

Updated guidance on Personal Protective Equipment (PPE) for clinicians – Intensive Care Society

Related: Clinical guidance for intensive care and anesthetics AND COVID-19: guidance for health professionals – GOV.UK

 


COVID-19 Testing: The Threat of False-Negative Results

13 Apr, 2020 | 00:04h | UTC

COVID-19 Testing: The Threat of False-Negative Results – Mayo Clinic Proceedings

Commentary: False-negative COVID-19 test results may lead to false sense of security – Mayo Clinic

 


New Clinical Score: Prediction for Progression Risk in Patients with COVID-19 Pneumonia

12 Apr, 2020 | 23:58h | UTC

Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score – Clinical Infectious Diseases

Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score – Comorbidity; older Age; Lower lymphocyte; and higher Lactate dehydrogenase at presentation were independent high-risk factors for COVID-19 progression. (via @veselov78 see Tweet)

Related: Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal – The BMJ

 


NICE Publishes new COVID-19 Guidelines on Cystic Fibrosis, COPD and Dermatological Conditions

10 Apr, 2020 | 03:22h | UTC

News Release: NICE publishes new COVID-19 guidelines on cystic fibrosis, chronic obstructive pulmonary disease (COPD) and dermatological conditions – National Institute for Health and Care Excellence

See New COVID-19 Rapid Guidelines: Community-based care of patients with chronic obstructive pulmonary disease (COPD) AND Cystic fibrosis AND Dermatological conditions treated with drugs affecting the immune response

See Other COVID-19 Rapid Guidelines: Severe asthma AND Managing suspected or confirmed pneumonia in adults in the community AND Rheumatological autoimmune, inflammatory and metabolic bone disorders AND Managing symptoms (including at the end of life) in the community AND Critical care in adults AND Hematopoietic stem cell transplantation AND Dialysis service delivery AND Delivery of radiotherapy AND Delivery of systemic anticancer treatments

 


New CDC Guidance for Critical Infrastructure Workers Who May Have Had Exposure to COVID-19

10 Apr, 2020 | 03:15h | UTC

Implementing Safety Practices for Critical Infrastructure Workers Who May Have Had Exposure to a Person with Suspected or Confirmed COVID-19 – Centers for Disease Control and Prevention

Commentary: White House Announces New Guidance For How Critical Employees Can Return To Work – NPR

 


AHA Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates with Suspected or Confirmed COVID-19

10 Apr, 2020 | 03:20h | UTC

Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With the Guidelines®-Resuscitation Adult and Pediatric Task Forces of the American Heart Association in Collaboration with the American Academy of Pediatrics, American Association for Respiratory Care, American College of Emergency Physicians, The Society of Critical Care Anesthesiologists, and American Society of Anesthesiologists: Supporting Organizations: American Association of Critical Care Nurses and National EMS Physicians – Circulation

News Release: Interim CPR guidelines address challenges of providing resuscitation during COVID-19 pandemic – American Heart Association

 

Related Commentary on Twitter

 


Consensus Recommendations: Caring for Patients with Pain During the COVID-19 Pandemic

10 Apr, 2020 | 03:13h | UTC

Caring for patients with pain during the COVID-19 pandemic: Consensus recommendations from an international expert panel – Anaesthesia

 


Approach to ST-segment Elevation, Myocardial Injury, and Suspected or Confirmed COVID-19 Patients

10 Apr, 2020 | 03:05h | UTC

ST-segment Elevation, Myocardial Injury, and Suspected or Confirmed COVID-19 Patients: Diagnostic and Treatment Uncertainties – Mayo Clinic Proceedings

News Release: Mayo Clinic experts offer guidance on treating COVID-19 patients with signs of acute heart attack – Mayo Clinic

 


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