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Internal Medicine

Antibody Tests Suggest that Coronavirus Infections Vastly Exceed Official Counts

20 Apr, 2020 | 00:25h | UTC

Antibody tests suggest that coronavirus infections vastly exceed official counts – Nature

See original preprint study: COVID-19 Antibody Seroprevalence in Santa Clara County, California – medRxiv

Author interview: Dr. John Ioannidis Announces Results of COVID-19 Serology Study (video)

Other commentaries: Far more people may have been infected by coronavirus in one California county, study estimates – CNN AND The number of coronavirus infections in Santa Clara, California may be up to 85 times higher than testing shows, according to new research – Business Insider AND Up to 4% of Silicon Valley is already infected with coronavirus – MIT Technology Review

 


The Promise and Peril of Antibody Testing for COVID-19

20 Apr, 2020 | 00:23h | UTC

The Promise and Peril of Antibody Testing for COVID-19 – JAMA

See also: Will antibody tests for the coronavirus really change everything? – Nature AND Antibody Test, Seen as Key to Reopening Country, Does Not Yet Deliver – The New York Times AND With Broad, Random Tests for Antibodies, Germany Seeks Path out of Lockdown

 


How Does Coronavirus Kill?

20 Apr, 2020 | 00:21h | UTC

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes – Science

 


Review: COVID-19 and Thrombotic or Thromboembolic Disease

20 Apr, 2020 | 00:18h | UTC

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up – Journal of the American College of Cardiology

Commentary: JACC Paper Outlines Implications, Considerations For Thrombotic Disease Patients During COVID-19 Pandemic – American College of Cardiology

 


The Science Underlying COVID-19: Implications for the Cardiovascular System

20 Apr, 2020 | 00:19h | UTC

The Science Underlying COVID-19: Implications for the Cardiovascular System – Circulation

 


Editorial: COVID-19 Pneumonia: ARDS or Not? – Critical Care

20 Apr, 2020 | 00:09h | UTC

Editorial: COVID-19 pneumonia: ARDS or not? – Critical Care

Related: COVID-19 pneumonia: different respiratory treatment for different phenotypes? – Intensive Care Medicine AND Covid-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine

 


Disruptive Modifications to Cardiac Critical Care Delivery During the Covid-19 Pandemic

20 Apr, 2020 | 00:14h | UTC

Disruptive Modifications to Cardiac Critical Care Delivery During the Covid-19 Pandemic: An International Perspective – Journal of the American College of Cardiology

 


What’s Happening with Remdesivir?

20 Apr, 2020 | 00:12h | UTC

What’s Happening With Remdesivir? – Science Translational Medicine

See also: Slow down your giddyup on Gilead news – Health News Review

 


Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective

20 Apr, 2020 | 00:07h | UTC

Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective – American Journal of Respiratory and Critical Care Medicine

 


The Pandemic’s Effects on Patients Without Covid-19

19 Apr, 2020 | 23:58h | UTC

The Untold Toll — The Pandemic’s Effects on Patients without Covid-19 – New England Journal of Medicine

 


Observational Study: Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Seems Safe Among Patients with Hypertension Hospitalized With COVID-19

20 Apr, 2020 | 00:01h | UTC

Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19 – Circulation Research

 


Systematic Review: Prophylactic Role of Chloroquine and Hydroxychloroquine in COVID‐19

19 Apr, 2020 | 23:57h | UTC

A systematic review of the prophylactic role of chloroquine and hydroxychloroquine in Coronavirus Disease‐19 (COVID‐19) – International Journal of Rheumatic Diseases

Commentary: ‘Dearth of evidence’ to support prophylactic chloroquine, hydroxychloroquine use for COVID-19 – Medicine Matters

 


COVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations

20 Apr, 2020 | 00:00h | UTC

COVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations – Circulation

Commentary: COVID-19 and Renin Angiotensin Blockers – American College of Cardiology

 


Coronavirus: Nine in 10 Dying Have Existing Illness

17 Apr, 2020 | 02:20h | UTC

Coronavirus: Nine in 10 dying have existing illness – BBC

Original Report: Deaths involving COVID-19, England and Wales: deaths occurring in March 2020 – Office for National Statistics

 


Study Commentary: Hydroxychloroquine Fails First Meaningful RCT

17 Apr, 2020 | 02:25h | UTC

Hydroxychloroquine fails first meaningful RCT – PulmCrit

Original Study: Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial

Related Commentary: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base – The Lancet Respiratory Medicine

 


Pathological Evidence of Pulmonary Thrombotic Phenomena in Severe COVID-19

17 Apr, 2020 | 02:24h | UTC

Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis

* We congratulate the authors for this significant contribution to the understanding of this disease.

 


Meta-Analysis: Hematologic, Biochemical and Immune Biomarker Abnormalities Associated with Severe Illness and Mortality in COVID-19

17 Apr, 2020 | 02:22h | UTC

Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis – Clinical Chemistry and Laboratory Medicine

“non-survivors compared to survivors had more significant increases in WBC count, total bilirubin, creatine kinase, serum ferritin, and interleukin 6 (IL-6), and more significant decreases in lymphocyte count and platelet count.”

 


CDC Guidance: Key Strategies to Prepare for COVID-19 in Long-term Care Facilities

17 Apr, 2020 | 02:18h | UTC

Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs) – Centers for Disease Control and Prevention

 


Innovation and Transformation in the Response to Covid-19: Seven Areas Where Clinicians Need to Lead

17 Apr, 2020 | 02:11h | UTC

Innovation and Transformation in the Response to Covid-19: Seven Areas Where Clinicians Need to Lead – NEJM Catalyst

 


Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date

17 Apr, 2020 | 02:08h | UTC

Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date – American Journal of Roentgenology

Commentary: AJR review of COVID-19 studies cautions against chest CT for coronavirus diagnosis – American Roentgen Ray Society

 


Management of the Hospitalized COVID-19 Patient with Acute Cardiomyopathy or Heart Failure

17 Apr, 2020 | 02:05h | UTC

Management of the Hospitalized COVID-19 Patient With Acute Cardiomyopathy or Heart Failure – American College of Cardiology

 


German Recommendations for Critically Ill Patients with COVID 19

17 Apr, 2020 | 02:02h | UTC

German recommendations for critically ill patients with COVID‑19 – Medizinische Klinik – Intensivmedizin und Notfallmedizin

 


Review: Antidepressants for Irritable Bowel Syndrome

17 Apr, 2020 | 01:52h | UTC

Antidepressants for irritable bowel syndrome – Canadian Family Physician

 


Neurologic Features in Severe SARS-CoV-2 Infection

16 Apr, 2020 | 02:56h | UTC

Neurologic Features in Severe SARS-CoV-2 Infection – New England Journal of Medicine

Related Study: Neurologic Manifestations Common in Hospitalized Patients with Covid-19 (study and commentaries)

 


Pharyngitis: Approach to Diagnosis and Treatment

17 Apr, 2020 | 01:53h | UTC

Pharyngitis: Approach to diagnosis and treatment – Canadian Family Physician

 


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