Internal Medicine
Systematic Review | Bupropion and nortriptyline: an assessment of their effectiveness in smoking cessation
2 Jun, 2023 | 12:28h | UTCAntidepressants for smoking cessation – Cochrane Library
Consensus Document | Diagnosis and treatment of lupus nephritis
2 Jun, 2023 | 12:26h | UTC
M-A | Residual respiratory disability after successful treatment of pulmonary tuberculosis
2 Jun, 2023 | 12:20h | UTC
Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care
2 Jun, 2023 | 12:18h | UTC
Review | Interventional therapies for pulmonary embolism
2 Jun, 2023 | 12:16h | UTCInterventional therapies for pulmonary embolism – Nature Reviews Cardiology (if the link is paywalled, try this one)
Commentary on Twitter
In our latest Review, @FelixMahfoud et al. discuss interventional therapies for pulmonary embolism. Check it out here: https://t.co/sBDfnZno1q pic.twitter.com/XNLclSbjmr
— Nature Reviews Cardiology (@NatRevCardiol) May 14, 2023
Review | Subclinical hypothyroidism: let the evidence be your guide
2 Jun, 2023 | 12:08h | UTCSubclinical hypothyroidism: Let the evidence be your guide – Journal of Family Practice
Review | Medication-assisted recovery for opioid use disorder
2 Jun, 2023 | 12:03h | UTCMedication-assisted recovery for opioid use disorder: A guide – Journal of Family Practice
Review | These USPSTF recommendations should be on your radar
2 Jun, 2023 | 11:59h | UTCThese USPSTF recommendations should be on your radar – Journal of Family Practice
ASH 2023 Guidelines for management of venous thromboembolism | Thrombophilia testing
1 Jun, 2023 | 12:22h | UTC
AASLD-IDSA Guideline | Updated 2023 recommendations for the testing, management, and treatment of Hepatitis C virus infection
1 Jun, 2023 | 12:21h | UTC
RCT | Dupilumab improves lung function and reduces exacerbations in COPD patients with elevated eosinophils
1 Jun, 2023 | 12:20h | UTCDupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Dupilumab Improves Outcomes for COPD, Type 2 Inflammation in Randomized Trial – HCP Live
Commentary on Twitter
Presented at #ATS2023: In the BOREAS trial, dupilumab resulted in a lower annualized rate of exacerbations than placebo among patients with COPD and an elevated blood eosinophil count. Full trial results: https://t.co/9IWZr3YqsN
— NEJM (@NEJM) May 21, 2023
Phase 2b RCT | Danuglipron, an oral GLP-1R agonist, reduces body weight and improves glycemic control in type 2 diabetes
1 Jun, 2023 | 12:17h | UTC
SR | Systematic review finds 16.4-36.18 severe bleedings, 7.62-8.5 perforations per 10,000 colonoscopies
1 Jun, 2023 | 12:15h | UTC
Expert Consensus | Nephrotoxic potential of 195 medications in the non-intensive care setting
1 Jun, 2023 | 12:14h | UTC
M-A | Noninvasive ventilation in patients with acute hypoxemic respiratory failure
1 Jun, 2023 | 12:11h | UTC
Review | Deprescribing interventions for gabapentinoids in adults
1 Jun, 2023 | 12:05h | UTC
Guideline | Onychomycosis
1 Jun, 2023 | 12:01h | UTCGuideline onychomycosis – Journal of the German Society of Dermatology
RCT | Adapted mindfulness training shows efficacy in reducing elevated office blood pressure
1 Jun, 2023 | 12:03h | UTC
Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care
1 Jun, 2023 | 11:58h | UTCCommentary: Use of CRP testing reduced antibiotics for respiratory infections, trial finds – CIDRAP
Study finds potential glaucoma risk in patients using calcium channel blockers
1 Jun, 2023 | 11:51h | UTCCommentary: Calcium Channel Blocker Use Associated with Higher Prevalence of Glaucoma – HCP Live
RCT | Prophylactic platelet transfusion reduces CVC-related bleeding in patients with platelets 10-50 K/mm³
31 May, 2023 | 14:20h | UTCPlatelet Transfusion before CVC Placement in Patients with Thrombocytopenia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Withholding of prophylactic platelet transfusion before CVC placement in pts with a platelet count of 10,000 to 50,000 per cubic millimeter did not meet the predefined margin for noninferiority & resulted in more CVC-related bleeding events than prophylactic platelet transfusion.
— NEJM (@NEJM) May 27, 2023
RCT | Early initiation of DOACs not statistically superior to later use in atrial fibrillation-related stroke
31 May, 2023 | 14:17h | UTCEarly versus Later Anticoagulation for Stroke with Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
ELAN: Early DOACs Safe, May Help After Ischemic Stroke in AF Patients – TCTMD
Commentary on Twitter
Late breaking at #ESOC2023: In the ELAN trial, the estimated incidence of stroke, systemic embolism, hemorrhage, or death was 2.8 percentage points lower to 0.5 percentage points higher with early than with later use of direct oral anticoagulants. Full results:
— NEJM (@NEJM) May 24, 2023
RCT | P2Y12 inhibitors don’t improve outcomes in critically ill COVID-19 patients
31 May, 2023 | 14:13h | UTCSee also: Visual Abstract
Proposing a new five-type classification for glomerulonephritis based on pathogenesis, activity, and chronicity
31 May, 2023 | 14:11h | UTC
Commentary on Twitter
The five types of glomerulonephritis classified by pathogenesis, activity & chronicity (GN-AC)
🔓https://t.co/NYKBde4L1I
📸The major entities of GN
📸Autoantigens in autoimmune GN
📸Multilevel diagnostic algorithm of GN
📸Proposed GN-AC classification & reporting system for GN pic.twitter.com/shmLLhCfJk— NDT (@NDTsocial) May 24, 2023
Guidelines | Management of ascites in liver disease
31 May, 2023 | 14:08h | UTC