Internal Medicine
Carefully implemented infection-control measures can prevent COVID-19 transmission in hospitals
14 Sep, 2020 | 01:12h | UTCOriginal study: Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center – JAMA Network Open
A COVID-19 vaccine may be only 50% effective. Is that good enough?
14 Sep, 2020 | 01:03h | UTCA COVID-19 Vaccine May Be Only 50% Effective. Is That Good Enough? – NPR
Cochrane evidence on COVID-19: a round-up
11 Sep, 2020 | 01:47h | UTCCochrane evidence on COVID-19: a round-up – Evidently Cochrane
NSAIDs like ibuprofen not tied to severe COVID-19, death
11 Sep, 2020 | 01:42h | UTCNSAIDs like ibuprofen not tied to severe COVID-19, death – CIDRAP
Preliminary randomized trial evaluated recombinant human granulocyte colony–stimulating factor for patients with COVID-19 and lymphopenia
11 Sep, 2020 | 01:36h | UTCInvited Commentary: Immune Stimulation With Recombinant Human Granulocyte Colony–Stimulating Factor for Coronavirus Disease 2019 (COVID-19)—Beware of Blind Spots
Commentary on Twitter
Preliminary findings from a randomized clinical trial suggest that rhG-CSF treatment should be studied in larger trials and in a broader range of patients with #COVID19 https://t.co/SjsoWOkEXg
— JAMA Internal Medicine (@JAMAInternalMed) September 10, 2020
Bacterial and fungal superinfections in critically ill patients with COVID-19
11 Sep, 2020 | 01:28h | UTC
Commentary on Twitter
Bacterial/fungal superinfections in critically ill #COVID19 pts: true prevalence still elusive. Underestimation of late superinfection risk may occur in #ICU; confounding factors also hamper identification of most frequently associated bacteria #COVIDFOAM https://t.co/iDAyOwYekr pic.twitter.com/Z7N4V7tc7q
— Intensive Care Medicine (@yourICM) September 10, 2020
Systematic review: Blood pressure targets for the treatment of people with hypertension and cardiovascular disease
11 Sep, 2020 | 01:16h | UTCSummary: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
Our latest @cochranecollab review update finds insufficient evidence to "justify lower blood pressure targets (135/85 mmHg or less) in people with hypertension and established cardiovascular disease"https://t.co/Ki8mwkRp0e#HTNEvidence #hypertension pic.twitter.com/Y9V12OaqZP
— Cochrane Hypertension (@CochraneHTN) September 9, 2020
New easy-to-use score for predicting risk of death in patients hospitalized with Covid-19
10 Sep, 2020 | 09:51h | UTCCommentaries: Discovery of four COVID-19 risk groups helps guide treatment – University of Edinburgh AND Expert reaction to a study looking at predicting the risk of death in hospitalised COVID-19 patients – Science Media Centre
Commentary on Twitter
NEW #BMJResearch finds that an easy-to-use score for predicting risk of death in adult patients admitted to hospital with #COVID19 outperforms existing scores and can be used to support treatment decisions @ProfCalumSemple @ISARIC1
https://t.co/2J9S3mqG5h— The BMJ (@bmj_latest) September 10, 2020
[Abstract Only] Meta-analysis: Effects of intensive blood pressure treatment on orthostatic hypotension
11 Sep, 2020 | 01:14h | UTC
Commentary on Twitter
Our article is out in @AnnalsofIM #Hypertension20! In this individual participant meta-analysis, more intensive blood pressure treatment did not increase #orthostatichypotension.
Effects of Intensive Blood Pressure Treatment on Orthostatic Hypotension https://t.co/UBoNjgCTjq
— Stephen Juraschek MD, PhD, FAHA, AHSCP-CHS (@spjuraschek) September 10, 2020
Why COVID-19 is more deadly in people with obesity—even if they’re young
10 Sep, 2020 | 09:47h | UTCWhy COVID-19 is more deadly in people with obesity—even if they’re young – Science
Characteristics, comorbidities, and outcomes in a multicenter registry of patients with HIV and Covid-19
10 Sep, 2020 | 09:38h | UTC
Commentary on Twitter
🔥REDCap Data 🔥
A new multicenter registry
Severe clinical outcomes occurred commonly in people with HIV& #COVID19
The risk for poor outcomes was higher in those with comorbidities & lower CD4 cell counts, despite HIV viral suppression. @dr_dimadandachi https://t.co/Mg9lZgYxZy pic.twitter.com/GhBAD2ynqs— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 9, 2020
Link between fluoroquinolones, aorta problems may not be as strong as thought
10 Sep, 2020 | 09:31h | UTCLink between fluoroquinolones, aorta problems may not be as strong as thought – CIDRAP
Original Studies: Association of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection – JAMA Internal Medicine AND Association of Infections and Use of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection
Interactive calculator for interpreting Covid-19 antibody test results
9 Sep, 2020 | 09:12h | UTCTesting for SARS-CoV-2 antibodies – The BMJ
Commentary on Twitter
#BMJInfographic Try out this new interactive calculator for interpreting covid-19 antibody test results @will_s_t https://t.co/t0Ha5zMlg1 pic.twitter.com/TAjVLog3A1
— The BMJ (@bmj_latest) September 8, 2020
WHO: More than 3 billion people protected from harmful trans-fat in their food
10 Sep, 2020 | 09:25h | UTCReport: Countdown to 2023: WHO report on global trans-fat elimination 2020 – World Health Organization
Commentary on Twitter
More than 3⃣ billion people across 5⃣8⃣ countries are now protected from harmful trans-fat in their food since the launch of WHO’s global #REPLACEtransfat initiative.
More details 👉https://t.co/3E5NIo8Y9Z #BeatNCDs pic.twitter.com/OHevkpBgaj
— World Health Organization (WHO) (@WHO) September 9, 2020
AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction in participant in the U.K.
9 Sep, 2020 | 09:45h | UTC
Commentary on Twitter
BREAKING: AstraZeneca's #Covid19 vaccine trials have been paused as the company investigates a serious adverse event the occurred in the UK. Not clear if the unexplained illness is linked to the vaccine, or what it was. https://t.co/wGqvvXIBTD
— Helen Branswell 🇨🇦 (@HelenBranswell) September 8, 2020
[Preprint] Randomized trial: Convalescent plasma not associated with improved outcomes in Covid-19
9 Sep, 2020 | 09:41h | UTC
Commentary on Twitter
Convalescent Plasma Randomized Controlled Trial (PLACID Trial) in the Management of Moderate #COVID19 (pre-print)
👉 “not associated with reduction in mortality or progression to severe COVID-19”
Link: https://t.co/2ZXnfemsas@GermHunterMD @MackayIM @CT_Bergstrom #IDTwitter pic.twitter.com/yZuOxVhbjL
— Alvin (@alvie_barr) September 8, 2020
Review: Physical medicine and rehabilitation and pulmonary rehabilitation for COVID-19
9 Sep, 2020 | 09:30h | UTC
IDSA Guidance on the treatment of antimicrobial resistant gram-negative infections
9 Sep, 2020 | 09:24h | UTCNews Release: IDSA Releases Guidance On Treatment Of Antimicrobial-Resistant Infections
Commentary on Twitter
The new @IDSAInfo guidance document on the treatment of MDR GN infections is 🔥🔥🔥. This a really practical/pragmatic document and will be of great use to frontline clinicianshttps://t.co/Eoz2vEHppb
— Mike Stevens (@Dr_Mike_Stevens) September 8, 2020
Perspective: “When will WE have a vaccine?” — understanding questions and answers about Covid-19 vaccination
9 Sep, 2020 | 09:37h | UTC
Commentary on Twitter
People inquiring about Covid-19 vaccines often want to know when the public can be confident that available vaccines are safe and effective, when a vaccine will be available to people like them, and when uptake will be high enough to enable a return to prepandemic life. #COVID19
— NEJM (@NEJM) September 8, 2020
An ethical framework for global vaccine allocation
8 Sep, 2020 | 01:24h | UTCAn ethical framework for global vaccine allocation – Science
Commentary: Who should get the COVID-19 vaccine first? – University of Pennsylvania School of Medicine
Commentaries on Twitter
How would #COVID19 vaccines be distributed fairly across the globe once they are made available? Prominent philosophers and bioethicists outline the "Fair Priority Model", a 3-phase plan for vaccine distribution in @ScienceMagazine. https://t.co/1gdErzkRRh
— Stanford Ethics (@StanfordEthics) September 7, 2020
A new, three-phase plan for vaccine distribution for #COVID19—called the Fair Priority Model—is “the best embodiment of the ethical values of limiting harms…and recognizing equal concern for all people,” argues this #SciMagPolicyForum. Learn more: https://t.co/WKMvqKgDjl
— Science Magazine (@ScienceMagazine) September 7, 2020
Factors contributing to healthcare professional burnout during the COVID-19 pandemic: A rapid turnaround global survey
8 Sep, 2020 | 01:14h | UTC
COVID-19 is, in the end, an endothelial disease
8 Sep, 2020 | 01:11h | UTCCOVID-19 is, in the end, an endothelial disease – European Heart Journal
Commentary on Twitter
COVID as an infectious disease of the “endothelium”, the lining of blood vessels, transmitted pre-sympyomatically. Explains the sepsis syndrome; explains the clotting/bleeding; explains the kidney failure.
What a nasty, nasty disease.https://t.co/5hlfL5Iik9
— David Fisman (@DFisman) September 7, 2020
Meta-analysis: Chloroquine and Hydroxychloroquine do not improve outcomes in COVID-19
8 Sep, 2020 | 01:08h | UTCRelated Meta-analysis: Antirheumatic Disease Therapies for the Treatment of COVID‐19: A Systematic Review and Meta‐analysis – Arthritis & Rheumatology
Systematic review: Reduction in saturated fat intake for cardiovascular disease
8 Sep, 2020 | 01:07h | UTCReduction in saturated fat intake for cardiovascular disease – Cochrane Library
Summary: Effect of cutting down on the saturated fat we eat on our risk of heart disease – Cochrane Library
Randomized trial: Upper airway surgery vs. medical management for patients with moderate or severe obstructive sleep apnea who failed conventional treatment
8 Sep, 2020 | 01:04h | UTCEffect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Relief for people who struggle with CPAP masks – Flinders University
Author interview: Treating Obstructive Sleep Apnea
Editorial: Upper Airway Surgery for Obstructive Sleep Apnea (free for a limited period)
Commentary on Twitter
In this preliminary report of the SAMS RCT of adults w moderate or severe #sleepapnea in whom #CPAP failed, combined palatal and tongue surgery reduced the number of apnea-hypopnea events and sleepiness at 6 mos compared w medical management https://t.co/jiU3hMn9ju #ERSCongress
— JAMA (@JAMA_current) September 4, 2020