Internal Medicine
Cohort study: Risk for serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis
7 Oct, 2020 | 08:53h | UTCCommentaries: Glucocorticoids associated with increased risk for infection, even at low doses – American College of Physicians AND Even low-dose glucocorticoids raise serious infection risk in RA patients – medwire News
Commentary on Twitter
ICYMI: #Glucocorticoids are associated with an increased risk for infection, even at doses as low as 5mg or less per day https://t.co/pm9Q72mvhT. pic.twitter.com/rM7GdHkbwW
— Annals of Int Med (@AnnalsofIM) September 24, 2020
Updated CDC Guidance: How COVID-19 Spreads
6 Oct, 2020 | 00:59h | UTCHow COVID-19 Spreads – Centers for Disease Control and Prevention
Commentary: CDC revises coronavirus guidance to acknowledge that it spreads through airborne transmission – CNBC
Long-term health consequences of COVID-19
6 Oct, 2020 | 00:58h | UTCLong-term Health Consequences of COVID-19 – JAMA
Commentary on Twitter
Persistent post-COVID symptoms could be the from direct tissue invasion by the virus, profound inflammation & cytokine storm, related immune system damage, hypercoagulable state, or some combination https://t.co/G8tI9U3TaL @CarlosdelRio7 lfcollins_md @PreetiNMalani
— JAMA (@JAMA_current) October 5, 2020
Meta-analysis: Risk of venous thromboembolism in patients with COVID‐19
6 Oct, 2020 | 00:54h | UTC
Commentaries on Twitter
In a new #RPTH paper, researchers performed a meta-analysis of #VTE risk in #COVID19 patients: 22.7% prevalence in ICU vs. 7.9% in non-ICU patients. Other subgroup analyses reveal heterogeneity and interesting trends…@Cihan_Ay_MD @FlorianMoik NEW: https://t.co/24IWOm5qTe pic.twitter.com/HjnSYq9YKz
— RPTH (@RPTHjournal) September 30, 2020
Meta-analysis of #clotting events in 66 studies including 28173 patients with #COVID19. High #VTE & #PE prevalence in ICU patients indicates a need for thromboprophylaxis research! Read the results at #RPTH by @Cihan_Ay_MD @FlorianMoik https://t.co/24IWOlNPuE @thrombosisday pic.twitter.com/V4Pn2ssBH3
— RPTH (@RPTHjournal) October 5, 2020
What we have found was a trend of decreased VTE rates over time. Earlier studies reported slightly higher VTE rates than more recent ones. What could be the reason? Experience dealing with COVID19 and improved preventive strategies? https://t.co/YDjRyvNmK6 https://t.co/y3Uj5x3QRI pic.twitter.com/0HcFQvMJB8
— Cihan Ay (@Cihan_Ay_MD) September 26, 2020
Changes in adult alcohol use and consequences during the COVID-19 pandemic in the US
6 Oct, 2020 | 00:56h | UTCCommentaries: Americans over 30 have been drinking more during the coronavirus pandemic, research shows – CNN AND Adult Alcohol Use Has Increased During the COVID-19 Pandemic – NEJM Journal Watch AND Americans Have Turned To Alcohol During The Coronavirus Pandemic, And It’s Concerning – Forbes
Commentary on Twitter
Survey study shows Americans increased their frequency of alcohol consumption during #COVID19, compared with a year earlier. Women also reported increases in days of heavy drinking and in alcohol-related problems. @MichaelSPollard https://t.co/TVjmpoj9ja
— JAMA Network Open (@JAMANetworkOpen) September 30, 2020
Survival of SARS-CoV-2 and influenza virus on the human skin: Importance of hand hygiene in COVID-19
6 Oct, 2020 | 00:52h | UTC
Commentary on Twitter
https://twitter.com/DrZoeHyde/status/1313098114958417921
Report: Adolescent with COVID-19 as the source of an outbreak at a 3-week family gathering
6 Oct, 2020 | 00:50h | UTC
A ‘herd mentality’ can’t stop the COVID-19 pandemic. Neither can a weak vaccine
6 Oct, 2020 | 00:53h | UTC
[Abstract Only] A Randomized trial comparing antibiotics with appendectomy for appendicitis
6 Oct, 2020 | 00:44h | UTCA Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Benefits, risks seen with antibiotics-first for appendicitis – University of Washington School of Medicine
Infographic: Deciding Between Antibiotics & Surgery for Appendicitis: Findings from the CODA Study
Commentary on Twitter
For the treatment of appendicitis, antibiotics noninferior to appendectomy on the basis of results of a standard health-status measure. In the antibiotics group, nearly 3 in 10 participants had undergone appendectomy by 90 days. #ACSCC20
— NEJM (@NEJM) October 5, 2020
Systematic review: Carotid endarterectomy for symptomatic carotid stenosis
6 Oct, 2020 | 00:10h | UTCCarotid endarterectomy for symptomatic carotid stenosis – Cochrane Library
Systematic review: Sublingual immunotherapy for asthma
6 Oct, 2020 | 00:11h | UTCSublingual immunotherapy for asthma – Cochrane Library
Summary: Sublingual immunotherapy for asthma – Cochrane Library
KDOQI clinical practice guideline for nutrition in CKD: 2020 update
6 Oct, 2020 | 00:08h | UTC
Review: Prehabilitation for the Anesthesiologist
6 Oct, 2020 | 00:07h | UTCPrehabilitation for the Anesthesiologist – Anesthesiology
Commentary on Twitter
Review by Dr. Carli @mcgillanesth focuses on fast-track and enhanced recovery after surgery protocols https://t.co/ItIe8RLDL7 pic.twitter.com/lGhq8Xll7I
— Anesthesiology (@_Anesthesiology) August 28, 2020
Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection
4 Oct, 2020 | 23:36h | UTCCommentary: Mysterious inflammatory syndrome tied to COVID-19 strikes adults as well as kids – Live Science
Commentary on Twitter
A new @CDCMMWR finds that adults who had #COVID19 can develop a condition similar to multisystem inflammatory syndrome in children and have severe outcomes including requiring intensive care. Learn more: https://t.co/dU1tS85Sj3. pic.twitter.com/RitCzJsLTL
— CDC (@CDCgov) October 2, 2020
Study: Four out of five people with sudden loss of smell or taste had COVID-19
4 Oct, 2020 | 23:30h | UTCCommentaries: Coronavirus: Loss of smell may be clearer sign than cough – BBC AND Coronavirus: Four out of five with sudden loss of smell or taste had COVID-19, study finds – Sky News
Commentary on Twitter
Four out of five people who experienced sudden loss of smell or taste had #COVID19, in a study by @ProfBatterhamMD and colleagues @ucl and @uclh #SARSCoV2
🔎 @PLOSMedicine paper: https://t.co/MoGTowbPus
📰 @SkyNews article: https://t.co/qgZJt9NHk6— PLOS (@PLOS) October 2, 2020
Perspective: What we know about vitamin D and Covid-19 (spoiler: not much)
4 Oct, 2020 | 23:28h | UTCWhat We Know About Vitamin D and Covid-19 – Medium
De-adopting low-value care: Evidence, eminence, and economics
4 Oct, 2020 | 23:20h | UTCDe-adopting Low-Value Care: Evidence, Eminence, and Economics – JAMA (free for a limited period)
Author Interview: De-Adopting Low-Value Care—Evidence, Eminence, and Economics
Commentary on Twitter
Evidence alone is NOT sufficient for many healthcare professionals to abandon low-value treatments that provide little or no benefit to patients.
Often it's only when their financial reimbursement is reduced or stopped that their use declines quickly. https://t.co/YiggZyqUMp
— The Sp⚽️rts Physio (@AdamMeakins) October 3, 2020
ASH 2020 guidelines for the management of deep vein thrombosis and pulmonary embolism
4 Oct, 2020 | 23:12h | UTC
Cohort study: Fecal microbiota transplant is highly effective in real-world practice
4 Oct, 2020 | 23:10h | UTCFecal Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry – Gastroenterology (link to abstract – $ for full-text)
Commentary: 9 in 10 Cured a Month After Fecal Microbiota Transplantation for C. diff – NEJM Journal Watch
Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults
4 Oct, 2020 | 22:48h | UTCMagnesium for skeletal muscle cramps – Cochrane Library
Video: Are “superspreaders” the key to stopping COVID?
2 Oct, 2020 | 09:31h | UTCAre “Superspreaders” The Key To Stopping COVID? – ZDoggMD Show
Related: This Overlooked Variable Is the Key to the Pandemic. It’s not R. – The Atlantic
Large study highlights the role of super-spreaders in Covid-19 transmission
2 Oct, 2020 | 09:32h | UTCEpidemiology and transmission dynamics of COVID-19 in two Indian states – Science
Commentaries: Largest COVID-19 contact tracing study to date finds children key to spread, evidence of superspreaders – Princeton University AND Largest study of COVID-19 transmission highlights essential role of super-spreaders – Los Angeles Times AND Huge Study of Coronavirus Cases in India Offers Some Surprises to Scientists – The New York Times
Commentary on Twitter
🚨Large study of >500,000 people in #India exposed to the #coronavirus found:
▶️Viral spread is driven by a small % of "superspreaders"
▶️Children & young adults are much more important to viral spread—especially within households—than previously reportedhttps://t.co/GziQHVixfL— Dena Grayson, MD, PhD drdenagrayson.bsky.social (@DrDenaGrayson) October 1, 2020
Ensuring uptake of vaccines against SARS-CoV-2
2 Oct, 2020 | 09:27h | UTCEnsuring Uptake of Vaccines against SARS-CoV-2 – New England Journal of Medicine
What does it mean if a vaccine is ‘successful’?
2 Oct, 2020 | 09:25h | UTCWhat Does It Mean If a Vaccine Is ‘Successful’? – Wired
Cohort study: In-hospital cardiac arrest in critically ill patients with Covid-19
2 Oct, 2020 | 09:24h | UTCCommentary: Cardiac arrest, poor survival rates common in sickest patients with COVID-19 – University of Michigan
Related Study: Clinical Outcomes of In-Hospital Cardiac Arrest in COVID-19 – JAMA Internal Medicine
Commentaries on Twitter
Cardiac arrest with severe #COVID19, in-hospital:
relatively common, very poor outcome, especially w/ ⬆️age
Two series:
701 patients (14%)https://t.co/Pu0V15lemL @bmj_latest @salimhayek @umichmedicine @MHealthLab
60 patients (5%)https://t.co/Exwk68VXgg @JAMAInternalMed pic.twitter.com/9cwS0HlNxz— Eric Topol (@EricTopol) October 2, 2020
Cardiac arrest is common in critically ill patients with #COVID19 and is associated with poor survival, particularly among patients aged 80 or older, finds new research @salimhayek
https://t.co/O2Z2K3TAeT— The BMJ (@bmj_latest) October 1, 2020