Internal Medicine
M-A | Anticoagulation options for continuous renal replacement therapy in critically ill patients
19 Jun, 2023 | 13:51h | UTC
Review | Role of GLP1 receptor agonists in achieving weight loss and improving CV outcomes in people with overweight and obesity
19 Jun, 2023 | 13:40h | UTC
Brief Review | Why is cuff size so important and other factors that affect accurate blood pressure measurement
16 Jun, 2023 | 14:12h | UTC
Cohort Study | Alcohol consumption and risks of more than 200 diseases in Chinese men
16 Jun, 2023 | 13:55h | UTCAlcohol consumption and risks of more than 200 diseases in Chinese men – Nature Medicine
News Release: Alcohol consumption increases the risks of over 60 diseases – University of Oxford
ATS Report | Rehabilitation for people with respiratory disease and frailty
16 Jun, 2023 | 13:51h | UTC
Single-center cohort study | Low-risk PE patients with concerning CT findings – increased hospitalization, but no increased risk of mortality
16 Jun, 2023 | 13:49h | UTCCommentary: Acute Low-Risk Pulmonary Embolism and Concerning CT Findings – American College of Cardiology
Evidence-based clinical practice guideline for deprescribing opioid analgesics
15 Jun, 2023 | 15:08h | UTC
RCT | Cannabis-based medicines show no significant relief for moderate-to-severe cancer pain
15 Jun, 2023 | 15:10h | UTCCannabis‐based medicines and medical cannabis for adults with cancer pain – Cochrane Library
Summary: Cannabis-based medicines for cancer pain – Cochrane Library
Cohort Study | Identification of an optimal threshold to define oliguria in critically ill patients
15 Jun, 2023 | 15:05h | UTC
Commentary on Twitter
Identification of an optimal threshold to define oliguria in critically ill patients
Read the full article: https://t.co/4msRdcWZYY@jlvincen @ISICEM #FOAMed #FOAMcc pic.twitter.com/5PfiXkE5FO
— Critical Care (@Crit_Care) June 9, 2023
RCT | No significant kidney outcome differences observed across glucose-lowering medications in T2D patients
15 Jun, 2023 | 15:02h | UTCComparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
See also: Visual Abstract
Commentaries:
No differences found in effects of secondary diabetes drugs on kidney outcomes – ACP Diabetes
Do glucose-lowering medications have different effects on kidney outcomes? – News Medical
SR | Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes
15 Jun, 2023 | 14:57h | UTC
M-A | Comparing non-invasive tests, histology for predicting non-alcoholic fatty liver outcomes
15 Jun, 2023 | 14:50h | UTC
Review | Fluid therapy for critically ill adults with sepsis
14 Jun, 2023 | 14:51h | UTCFluid Therapy for Critically Ill Adults With Sepsis: A Review – JAMA (free for a limited period)
Audio clinical review: Fluid Therapy for Critically Ill Adults With Sepsis – JAMA
Review | Acute graft-versus-host disease
14 Jun, 2023 | 14:20h | UTCAcute graft-versus-host disease – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Commentary on Twitter
Tissue damage resulting from allogenic hematopoietic cell transplantation conditioning regimens triggers cellular interactions and #inflammatory cascades that lead to acute #GraftVersusHost disease symptoms https://t.co/iHyUVoV75J pic.twitter.com/ob9X7zQWB8
— Nature Reviews Disease Primers (@DiseasePrimers) June 11, 2023
Cluster RCT | Effects of implementation of a supervised walking program in veterans affairs hospitals
14 Jun, 2023 | 14:17h | UTCEffects of Implementation of a Supervised Walking Program in Veterans Affairs Hospitals: A Stepped-Wedge, Cluster Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Supervised Walking Program Benefits Veterans Admitted to Hospital – Physician’s Weekly
Commentary on Twitter
A supervised #WalkingProgram known as #STRIDE reduced skilled nursing facility admissions among older adults. https://t.co/nvkzcx5eVE pic.twitter.com/UJnJMtaxXG
— Annals of Int Med (@AnnalsofIM) June 8, 2023
M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients
13 Jun, 2023 | 14:12h | UTC
Commentary on Twitter
In this systematic review and meta-analysis of 15 RCTs, oseltamivir was not associated with reduced risk of first hospitalization compared with placebo or standard of care among influenza-infected adult and adolescent outpatients. https://t.co/UEqsbA2JQZ
— JAMA Internal Medicine (@JAMAInternalMed) June 12, 2023
Review | Post-intensive care syndrome
13 Jun, 2023 | 13:44h | UTCPost-intensive care syndrome (PICS): recent updates – Journal of Intensive Care
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections
12 Jun, 2023 | 13:58h | UTCRelated:
2ry Analysis of a RCT | Metformin linked to 41% reduction in long COVID incidence in outpatient treatment
12 Jun, 2023 | 13:55h | UTCNews Release: Study shows metformin lowers the risk of getting long COVID – University of Minnesota Medical School
Commentary on Twitter
These data not persuasive. There are 6 different arms. 3 drugs. This is not the primary endpoint. No adjustment for multiple testing.
Even USFDA would not accept these data for regulatory approval, and they are basically working for Pharma at this pthttps://t.co/FZoxo9shtG
— Vinay Prasad MD MPH (@VPrasadMDMPH) June 9, 2023
Review | Volume management with kidney replacement therapy in the critically ill patient
12 Jun, 2023 | 13:43h | UTC
SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome
12 Jun, 2023 | 13:41h | UTC
Review | Acute dyspnea in the emergency department
12 Jun, 2023 | 13:33h | UTCAcute dyspnea in the emergency department: a clinical review – Internal and Emergency Medicine
Brief Review | Resistance to unfractionated heparin in the ICU: evaluation and management options
12 Jun, 2023 | 13:32h | UTCResistance to unfractionated heparin in the ICU: evaluation and management options – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
🩸 Resistance to unfractionated heparin in #ICU, evaluation & management options
💉 monitoring UFH
💉 mechanisms of resistance
💉 how to manage UFH resistance
PS check supplement table on IV anticoagulants in ICU#FOAMcc @JerroldLevy @Dr_Cit @foamecmo
🖇️ https://t.co/ojQw5On5ZL pic.twitter.com/0uPQuwUmOr— Intensive Care Medicine (@yourICM) June 7, 2023
Cohort Study | Pulmonary hypertension post-VTE linked to a twofold increase in long-term mortality
12 Jun, 2023 | 13:27h | UTC
Cohort Study | Prognostic model for predicting methotrexate toxicity in immune mediated inflammatory diseases
12 Jun, 2023 | 13:26h | UTCNews Release: New study reveals way to predict side-effect risk from common immune suppressant medication – University of Nottingham
Commentary: Prognostic model stratifies risk for methotrexate toxicity – ACP Internist