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Internal Medicine

COVID-19 in gastroenterology: Where are we now? Current evidence on the impact of COVID-19 in gastroenterology.

17 Sep, 2021 | 10:11h | UTC

COVID-19 in gastroenterology: Where are we now? Current evidence on the impact of COVID-19 in gastroenterology – UEG Journal

 

As Covid Cases Rise, So Do Hospital-Related Infections.

17 Sep, 2021 | 10:08h | UTC

As Covid Cases Rise, So Do Hospital-Related Infections – Wired

 

AAN Position Statement: Ethical Considerations in Dementia Diagnosis and Care.

17 Sep, 2021 | 10:04h | UTC

Ethical Considerations in Dementia Diagnosis and Care: AAN Position Statement – Neurology

 

Guideline: Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome.

17 Sep, 2021 | 10:07h | UTC

Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases – Hepatology

 

Review | Functional gastrointestinal disorders: History taking skills in practice.

17 Sep, 2021 | 09:54h | UTC

Functional gastrointestinal disorders: History taking skills in practice – Clinical Medicine Journal

 

Review | Thrombophilia testing in the era of direct oral anticoagulants.

17 Sep, 2021 | 09:53h | UTC

Thrombophilia testing in the era of direct oral anticoagulants – Clinical Medicine Journal

 

Case series: Vaccine-induced thrombocytopenia with severe headache may precede cerebral venous sinus thrombosis by several days – patients with severe headache 5 to 20 days after adenovirus vector vaccination against Covid-19 should undergo immediate testing for thrombocytopenia and d-dimer levels and, if available, testing for anti–PF4–heparin IgG antibodies.

16 Sep, 2021 | 10:14h | UTC

Vaccine-Induced Thrombocytopenia with Severe Headache – New England Journal of Medicine

 

Commentary on Twitter

 

Review | Acute myocarditis: etiology, diagnosis and management.

17 Sep, 2021 | 09:51h | UTC

Acute myocarditis: aetiology, diagnosis and management – Clinical Medicine Journal

 

COVID vaccine effects wane over time but still prevent death and severe illness.

16 Sep, 2021 | 10:10h | UTC

COVID vaccine effects wane over time but still prevent death and severe illness – The Conversation

Related:

Perspective | What we actually know about waning immunity.

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

Pfizer says it’s time for a Covid booster; FDA and CDC say not so fast.

 

An observational study in Israel suggests additional protection from a 3rd dose of the Pfizer vaccine in individuals 60 years of age or older.

16 Sep, 2021 | 10:13h | UTC

Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel – New England Journal of Medicine

 

State of the Art Review: Eosinophils in Health and Disease.

16 Sep, 2021 | 09:59h | UTC

Eosinophils in Health and Disease: A State-of-the-Art Review – Mayo Clinic Proceedings

 

Review: Is there an optimal antiplatelet strategy after gastrointestinal bleeding in patients with coronary artery disease?

16 Sep, 2021 | 09:57h | UTC

Is There an Optimal Antiplatelet Strategy after Gastrointestinal Bleeding in Patients with Coronary Artery Disease? – Cardiology

 

State of the Art Review: Screening and prevention of colorectal cancer.

16 Sep, 2021 | 10:01h | UTC

Screening and prevention of colorectal cancer – The BMJ (free for a limited period)

Related:

USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.

ACG Clinical Guidelines: Start colorectal cancer screening at 45

 

Systematic Review: Can electronic cigarettes help people stop smoking, and do they have any unwanted effects when used for this purpose?

16 Sep, 2021 | 09:55h | UTC

Summary: Can electronic cigarettes help people stop smoking, and do they have any unwanted effects when used for this purpose? – Cochrane Library

Original Study: Electronic cigarettes for smoking cessation – Cochrane Library

 

Commentary on Twitter

 

A guide to the treatment of cellulitis and other soft-tissue infections.

16 Sep, 2021 | 09:47h | UTC

A guide to the Tx of cellulitis and other soft-tissue infections – Journal of Family Practice

 

RCT: Remdesivir does not improve outcomes in patients admitted to hospital with COVID-19.

15 Sep, 2021 | 09:59h | UTC

Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial – The Lancet Infectious Diseases

Invited commentary: Remdesivir, on the road to DisCoVeRy – The Lancet Infectious Diseases

Related:

Systematic Review: “Remdesivir probably has little or no effect on all‐cause mortality at up to 28 days in hospitalized adults with SARS‐CoV‐2 infection. We are uncertain about the effects of remdesivir on clinical improvement and worsening”.

WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19

 

Review | Prevention of host-to-host transmission by SARS-CoV-2 vaccines.

15 Sep, 2021 | 09:16h | UTC

Prevention of host-to-host transmission by SARS-CoV-2 vaccines – The Lancet Infectious Diseases

Related:

Study ties COVID vaccines to lower transmission rates.

Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients”.

Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose

Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.

 

Ivermectin: Cochrane’s most talked about review so far, ever. Why?

15 Sep, 2021 | 09:07h | UTC

Ivermectin: Cochrane’s most talked about review so far, ever. Why? – Cochrane Library

Original review: Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.

 

Commentary on Twitter

 

CDC report finds unvaccinated people are 11 times more likely to die of COVID-19.

15 Sep, 2021 | 09:09h | UTC

Unvaccinated People Are 11 Times More Likely To Die Of COVID-19, New Research Finds – NPR

Original study: Monitoring Incidence of COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Status — 13 U.S. Jurisdictions, April 4–July 17, 2021 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 

The USPSTF maintains the recommendation to screen for chlamydia and gonorrhea in all sexually active women 24 years or younger and in women 25 years or older who are at increased risk for infection.

15 Sep, 2021 | 08:57h | UTC

Final Recommendation Statement: Screening for Chlamydia and Gonorrhea – U.S. Preventive Services Task Force

Editorial: Screening for Chlamydia and Gonorrhea – JAMA

Evidence Report : Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Screening for Chlamydia and Gonorrhea

JAMA Patient Page: Screening for Chlamydia and Gonorrhea

 

Management of high-risk pulmonary embolism in pregnancy.

15 Sep, 2021 | 08:43h | UTC

Management of high-risk pulmonary embolism in pregnancy – Thrombosis Research

 

An update on prevention of malaria in travelers.

15 Sep, 2021 | 08:39h | UTC

An update on prevention of malaria in travelers – Therapeutic Advances in Infectious Disease

Related: CDC Yellow Book

 

Report: Fully vaccinated people account for 1.2% of England’s Covid-19 deaths.

14 Sep, 2021 | 10:07h | UTC

Fully vaccinated people account for 1.2% of England’s Covid-19 deaths – The Guardian

Original Report: Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 2 July 2021 – Office for National Statistics

 

COVID-19 vaccine efficacy does not support boosters for general population, review concludes.

14 Sep, 2021 | 10:08h | UTC

News release: COVID-19 vaccine efficacy does not support boosters for general population, review concludes – The Lancet

Original article: Considerations in boosting COVID-19 vaccine immune responses – The Lancet

Commentaries:

FDA experts among group opposing US booster shot plan – Associated Press

FDA vaccine regulators argue against Covid-19 vaccine boosters in new international review – STAT

Global experts pan wider use of COVID vaccine booster dose – CIDRAP

Expert reaction to viewpoint article on COVID-19 booster vaccines for general populations – Science Media Centre

Boosters Are ‘Not Appropriate’ – Reach Unvaccinated First – Health Policy Watch

Data Doesn’t Support Need for COVID-19 Vaccine Boosters: Experts – HealthDay

In a new review, some F.D.A. scientists and others say boosters aren’t needed for the general population. – The New York Times

 

Covid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors.

14 Sep, 2021 | 10:05h | UTC

Covid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors – BBC

See also: Covid-19: Children aged 12-15 should be offered vaccine, say UK’s chief medical officers – The BMJ

 

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