Internal Medicine
Network Meta-Analysis: Effectiveness of heterologous and homologous covid-19 vaccine regimens.
1 Jun, 2022 | 12:00h | UTCNews Release: Three doses of the same or mixed covid jabs work equally well against infections – BMJ
Commentary: Three jabs best for preventing Covid infections, global analysis finds – The Guardian
Systematic Review: SARS-CoV-2 saliva testing using RT-PCR.
1 Jun, 2022 | 11:42h | UTC
Understanding base excess (BE): merits and pitfalls.
1 Jun, 2022 | 11:33h | UTCUnderstanding base excess (BE): merits and pitfalls – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Understanding base excess
🧪 valuable quantitative estimate of metabolic acid-base derangements, but not info on underlying mechanisms
🧪 standard BE composite marker: several components contribute; interpretation of isolated value very difficult#FOAMcc
🖇️https://t.co/T8pcVRrTgR pic.twitter.com/6TEFsFTJR1— Intensive Care Medicine (@yourICM) May 31, 2022
RCTs: Favipiravir treatment of uncomplicated influenza in adults.
1 Jun, 2022 | 11:27h | UTCCommentary: Mixed Bag for Antiviral Favipiravir in Flu — Two phase III trials show conflicting results on clinical improvement – MedPage Today (free registration required)
Retrospective Cohort Study: Colonoscopy surveillance following adenoma removal to reduce the risk of colorectal cancer.
1 Jun, 2022 | 11:17h | UTC
Cohort Study: Complicated carotid artery plaques and risk of recurrent ischemic stroke or TIA.
1 Jun, 2022 | 11:19h | UTCCommentary: Complicated Carotid Plaques and Risk of Recurrent Ischemic Stroke or TIA – American College of Cardiology
Commentary on Twitter
#ESOC2022 #JACC SimPub: Complicated #CarotidArtery plaques increase risk of recurrent ischemic #stroke or transient #ischemicattack in pts w/ ischemic stroke & undetermined stroke etiology. https://t.co/io9aUdX8cT
Editorial: https://t.co/H5ReNFnEAS #StrokeMonth #CardioTwitter pic.twitter.com/aYZEPrMmeZ
— JACC Journals (@JACCJournals) May 3, 2022
Update on perioperative management of patients undergoing surgery for liver cancer.
1 Jun, 2022 | 11:11h | UTC
Cohort Study: Taking 5-ARIs for BPH is not associated with increased mortality in prostate cancer.
1 Jun, 2022 | 10:59h | UTCNews Release: Taking 5-ARIs for BPH is not associated with increased mortality in prostate cancer – Karolinska Institute
Original Study: Association of 5α-Reductase Inhibitors With Prostate Cancer Mortality – JAMA Oncology (link to abstract – $ for full-text)
Authors Interview: Association of 5α-Reductase Inhibitors With Prostate Cancer Mortality – JAMA
Commentary: Large study finds no increased risk for prostate cancer death with 5-ARI use – medwire News
Commentary on Twitter
This large population-based cohort study found that men treated with 5α-reductase inhibitors had no increased risk of dying from #prostatecancer, on the contrary indicating a decreased risk with longer treatment duration. https://t.co/y8HlpthNI9 #PCSM #GUCSM
— JAMA Oncology (@JAMAOnc) May 19, 2022
Review | Long-term cardiac monitoring after embolic stroke of undetermined source. Search longer – look harder.
1 Jun, 2022 | 10:52h | UTC
Cohort Study: Intraoperative hypotension is associated with persistent acute kidney disease after noncardiac surgery.
1 Jun, 2022 | 10:53h | UTC
Long-term impact of Helicobacter pylori eradication therapy on gastric cancer incidence and mortality in healthy infected individuals: A meta-analysis beyond 10 years of follow-up.
31 May, 2022 | 11:47h | UTC
Commentary from the author on Twitter (thread – click for more)
https://twitter.com/alex_ford12399/status/1527601814765551616
Cohort Study: A multisystem, cardio-renal investigation of post-COVID-19 illness.
31 May, 2022 | 11:44h | UTCA multisystem, cardio-renal investigation of post-COVID-19 illness – Nature Medicine
Commentaries:
Lingering Symptoms After COVID-19 Tied to Heart, Lung, and Kidney Injury – TCTMD
Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome – News Medical
Commentary on Twitter
Deep clinical phenotyping at 28-60 days post-discharge of patients who had been hospitalized with #COVID19 and subsequent long-term follow up with electronic health records reveals evidence of persistent cardio-renal involvement. #postCOVID @ColinBerryMD https://t.co/uLxtj0b1gJ
— Nature Medicine (@NatureMedicine) May 30, 2022
Special Series: Pain management in the ICU.
31 May, 2022 | 11:52h | UTCEditorial: Acute Pain Management – ICU Management & Practice
Series:
Pain Assessment in Critical Illness
Sedation, Analgesia and Respiratory Drive in Mechanically Ventilated Adults
Pain Management Specificities in Critically Ill Patients With Obesity
Analgesia, Sedation and Neuromuscular Blockade in Critically Ill Patients
Pain Management in Paediatric Critical Care
High blood pressure: what can we do to prevent it?
31 May, 2022 | 11:35h | UTCHigh blood pressure: what can we do to prevent it? – Evidently Cochrane
Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19.
31 May, 2022 | 11:40h | UTCSummary: How accurate are symptoms and medical examination to diagnose COVID-19? – Cochrane Library
Commentary on Twitter (thread – click for more)
UPDATE JUST PUBLISHED – How accurate are symptoms & medical examination to diagnose #COVID19?
📚@Cochrane_IDG authors looked at the evidence from 42 studies with 52,608 participants in this review.
➡️https://t.co/pbP9BX5Xkm 1/5 pic.twitter.com/bjfb6yVTGg— The Cochrane Library (@CochraneLibrary) May 20, 2022
Most doctors still believe in prescribing unnecessary antibiotics to treat asymptomatic bacteriuria, study suggests.
31 May, 2022 | 11:31h | UTC
Commentary on Twitter
🆕💥💥@jamanetworkopen @dr_dmorgan et Al
In this survey study of 551 primary care clinicians, 392 (71%) reported that they would prescribe antibiotics for asymptomatic bacteriuria, shocking? #IDTwitter @BradSpellberg @DrToddLee @InfectiousDz @bwtrautnerhttps://t.co/tekcQVsfqk pic.twitter.com/1fRakHgjU7— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 27, 2022
Systematic Review: Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease.
31 May, 2022 | 11:16h | UTC
Commentary on Twitter
Is magnesium sulfate effective for #COPD flare‐ups? @CochraneAirways systematic review evaluates the evidence from 11 studies. ''Magnesium infusion may ⬇️ hospital admissions, shorten length of hospital stay & improve breathlessness compared to placebo' https://t.co/ZUPVrcdRzk pic.twitter.com/IxBGlnU6FZ
— The Cochrane Library (@CochraneLibrary) May 30, 2022
RCT: Rivaroxaban vs. placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer.
31 May, 2022 | 11:19h | UTC
Delirium: How can we protect our patients? Detection and treatment strategies.
31 May, 2022 | 11:10h | UTCRelated:
Less pharmacotherapy is more in delirium – Intensive Care Medicine
Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Hypoxia in the ED setting: systematic approach and management.
31 May, 2022 | 10:56h | UTCHypoxia in the ED Setting: Systematic Approach and Management – emDocs
RCT: Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalized patients with pneumonia at risk of Gram-negative bacterial infection.
31 May, 2022 | 10:55h | UTCFast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW Research—Multiplex bacterial PCR examination of bronchoalveolar lavage decreases duration of inappropriate antibiotic therapy of pts admitted to hospital w/ pneumonia & at risk of Gram-negative rod infection
From @AndreiMDarie & colleagues https://t.co/jnBak5SkJo pic.twitter.com/Py28aFqMw9
— The Lancet Respiratory Medicine (@LancetRespirMed) May 25, 2022
M-A: Efficacy of different doses of Daprodustat for anemic non-dialysis patients with chronic kidney disease.
31 May, 2022 | 10:43h | UTCRelated Studies:
[News release – not published yet] RCT: Doxycycline after unprotected sex significantly reduced STIs – study of men who have sex with men and transgender women stopped early for effectiveness.
30 May, 2022 | 11:57h | UTC
Evidence-based recommendations on texture modified foods and thickened liquids for adults with oropharyngeal dysphagia – “There is no convincing evidence that thickened liquid or texture modified diet prevents death or pneumonia nor improves the quality of life, nutritional status, or oral intake in individuals with OD”.
30 May, 2022 | 11:54h | UTC
Consensus: nephrotoxic potential of 167 drugs in adult critically ill patients.
30 May, 2022 | 11:50h | UTCConsensus Obtained for the Nephrotoxic Potential of 167 Drugs in Adult Critically Ill Patients Using a Modified Delphi Method – Drug Safety (if the link is paywalled, try this one)