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Vaccines

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.

20 Jul, 2022 | 12:27h | UTC

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics – American Journal of Obstetrics and Gynecology

Commentary: Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length – News Medical

 


Who to vaccinate first? A peek at decision-making in a pandemic.

19 Jul, 2022 | 13:40h | UTC

Who to vaccinate first? A peek at decision-making in a pandemic – Nature

 


A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology.

19 Jul, 2022 | 13:38h | UTC

A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology – BMJ Global Health

 


WHO | COVID-19 pandemic fuels largest continued backslide in vaccinations in three decades.

18 Jul, 2022 | 11:45h | UTC

COVID-19 pandemic fuels largest continued backslide in vaccinations in three decades – World Health Organization

Commentaries:

WHO, UNICEF sound alarm over childhood immunization slide – CIDRAP

Expert reaction to data from WHO and UNICEF on global childhood vaccination rates, including against diphtheria, tetanus and pertussis (DTP3); HPV; and measles – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 


Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.

18 Jul, 2022 | 11:34h | UTC

Reactogenicity of Simultaneous COVID-19 mRNA Booster and Influenza Vaccination in the US – JAMA Network Open

Commentaries:

More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP

Reactogenicity and Concomitant Administration of the COVID-19 Booster and Influenza Vaccine – JAMA Network Open

 


Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.

18 Jul, 2022 | 11:30h | UTC

Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review – The BMJ

News Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom

 


7 of your most pressing monkeypox vaccine questions, answered – “We have safe, effective options — but in short supply”.

15 Jul, 2022 | 13:00h | UTC

7 of your most pressing monkeypox vaccine questions, answered – Vox

Related:

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


FDA authorizes emergency use of Novavax COVID-19 vaccine.

14 Jul, 2022 | 13:01h | UTC

Coronavirus (COVID-19) Update: FDA Authorizes Emergency Use of Novavax COVID-19 Vaccine, Adjuvanted – U.S. Food & Drug Administration

Commentaries:

FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT

US regulators OK new COVID-19 shot option from Novavax – Associated Press

 


Nationwide cohort study | Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines.

14 Jul, 2022 | 12:52h | UTC

Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines: nationwide cohort study – The BMJ

 


European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.

11 Jul, 2022 | 12:41h | UTC

European Medicines Agency Recommends Second COVID Booster for People Over 60 – as WHO Ponders Guidance – Health Policy Watch

 


Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.

7 Jul, 2022 | 13:00h | UTC

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

 


Review | The vaccine-hesitant moment.

6 Jul, 2022 | 11:49h | UTC

The Vaccine-Hesitant Moment – New England Journal of Medicine


Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.

6 Jul, 2022 | 11:48h | UTC

Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines – Nature Communications


Opinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.

4 Jul, 2022 | 12:53h | UTC

FDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT


Cohort Study: Effectiveness of Pfizer, Moderna, and AstraZeneca vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting.

1 Jul, 2022 | 11:37h | UTC

Effectiveness of BNT162b2, mRNA-1273, and ChAdOx1-S vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting: cohort study – BMJ Medicine

 

Commentary on Twitter

 


RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.

29 Jun, 2022 | 12:10h | UTC

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial – The Lancet Respiratory Medicine

News Releases:

Interrupting the treatment of vulnerable people on immune-suppressing medicines, doubles their antibody response to COVID-19 booster vaccination – University of Nottingham

Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London

Commentaries:

Improving COVID-19 vaccine immunogenicity by interrupting methotrexate treatment – The Lancet Respiratory Medicine

Covid-19: Pausing immune suppressing drugs enhances antibody response to boosters, study shows – The BMJ

Related Study: Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial – Annals of Rheumatic Diseases

 

Commentary on Twitter

 


An analysis of SARS-CoV-2 vaccine reactogenicity: variation by type, dose, and history, severity, and recency of prior SARS-CoV-2 infection.

29 Jun, 2022 | 11:52h | UTC

An Analysis of SARS-CoV-2 Vaccine Reactogenicity: Variation by Type, Dose, and History, Severity, and Recency of Prior SARS-CoV-2 Infection – Open Forum Infectious Diseases

 


Cohort Study: Association of receipt of the fourth BNT162b2 dose with omicron infection and COVID-19 hospitalizations among residents of long-term care facilities.

28 Jun, 2022 | 11:08h | UTC

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Commentary: Fourth Dose of BNT162b2 Prevents Severe COVID-19 in Nursing Home Residents – HealthDay

 

Commentary on Twitter

 


Epidemiology of myocarditis and pericarditis following mRNA vaccination by vaccine product, schedule, and interdose interval among adolescents and adults in Ontario, Canada.

27 Jun, 2022 | 11:51h | UTC

Epidemiology of Myocarditis and Pericarditis Following mRNA Vaccination by Vaccine Product, Schedule, and Interdose Interval Among Adolescents and Adults in Ontario, Canada – JAMA Network Open

Commentary: Young Men’s Myocarditis Risk 5 Times Higher With Moderna vs Pfizer Vax — But Canadian study finds that 8-week interval before second dose attenuates some of the risk – MedPage Today (free registration required)

 


[Press Release – not published yet]: RCT: Sanofi-GSK report its vaccine targeted against ancestral and Beta strains had an overall efficacy of 72% against the Omicron variant.

27 Jun, 2022 | 11:52h | UTC

Press Release: Sanofi-GSK first to report a successful efficacy study against Omicron with COVID-19 Beta-containing vaccine – Sanofi

Commentaries: Bivalent COVID Vax Gets Phase III Win Against Omicron, Companies Say — Sanofi, GSK boast of 72% efficacy against Omicron variant – MedPage Today (free registration required)

 


Phase 2a RCT: Vaccine efficacy in adults in a respiratory syncytial virus challenge study.

27 Jun, 2022 | 11:21h | UTC

Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study -New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Challenge Study Shows Efficacy of RSV Vaccine in Healthy Adults – HealthDay

 

Commentary on Twitter

 


EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.

24 Jun, 2022 | 11:17h | UTC

EULAR/PRES recommendations for vaccination of paediatric patients with autoimmune inflammatory rheumatic diseases: update 2021 – Annals of Rheumatic Diseases

 


Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.

22 Jun, 2022 | 12:07h | UTC

Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA: a cohort study in claims databases – The Lancet

Commentaries:

COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet

Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology

Related:

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Comparing the Pfizer and Moderna Covid vaccines for young children.

22 Jun, 2022 | 12:02h | UTC

Comparing the Pfizer and Moderna Covid vaccines for young children – STAT

Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP

 


WHO Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines.

20 Jun, 2022 | 10:42h | UTC

Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines – World Health Organization

See also: Interim statement on the composition of current COVID-19 vaccines – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


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