Vaccines
Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.
25 Jul, 2022 | 13:03h | UTCRelated:
Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.
25 Jul, 2022 | 12:54h | UTC
Commentary on Twitter
This cohort study found the nationwide implementation of hepatitis B vaccination (1984) and antiviral treatment programs (2003) was followed by dramatic reductions in the burden of end-stage liver disease in Taiwan. https://t.co/Qnei2abi85
— JAMA Network Open (@JAMANetworkOpen) July 18, 2022
Cohort Study | Effectiveness of the Pfizer vaccine against Omicron in children 5 to 11 years of age.
21 Jul, 2022 | 13:28h | UTC
A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.
20 Jul, 2022 | 12:27h | UTC
Who to vaccinate first? A peek at decision-making in a pandemic.
19 Jul, 2022 | 13:40h | UTCWho to vaccinate first? A peek at decision-making in a pandemic – Nature
A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology.
19 Jul, 2022 | 13:38h | UTC
WHO | COVID-19 pandemic fuels largest continued backslide in vaccinations in three decades.
18 Jul, 2022 | 11:45h | UTCCommentaries:
WHO, UNICEF sound alarm over childhood immunization slide – CIDRAP
Commentary on Twitter (thread – click for more)
1⃣8⃣ million children did not receive a single vaccine in 2021 – the largest ↘️ in 29 years, due to:
🔸 #COVID19-related disruptions
🔸 emergencies
🔸 misinformation undermining vaccine acceptance & demandWHO & @UNICEF sound the alarm 🚨
🆕 data on global vaccine coverage ⬇️
— World Health Organization (WHO) (@WHO) July 14, 2022
Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.
18 Jul, 2022 | 11:34h | UTCCommentaries:
More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP
Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.
18 Jul, 2022 | 11:30h | UTCNews Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom
7 of your most pressing monkeypox vaccine questions, answered – “We have safe, effective options — but in short supply”.
15 Jul, 2022 | 13:00h | UTC7 of your most pressing monkeypox vaccine questions, answered – Vox
Related:
How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic
Prevention and Treatment of Monkeypox – Drugs
Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP
No room for complacency – World Health Organization
Multi-country monkeypox outbreak: situation update – World Health Organization
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
FDA authorizes emergency use of Novavax COVID-19 vaccine.
14 Jul, 2022 | 13:01h | UTCCommentaries:
FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT
US regulators OK new COVID-19 shot option from Novavax – Associated Press
Nationwide cohort study | Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines.
14 Jul, 2022 | 12:52h | UTC
European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.
11 Jul, 2022 | 12:41h | UTC
Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.
7 Jul, 2022 | 13:00h | UTC
Review | The vaccine-hesitant moment.
6 Jul, 2022 | 11:49h | UTCThe Vaccine-Hesitant Moment – New England Journal of Medicine
Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.
6 Jul, 2022 | 11:48h | UTCOpinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.
4 Jul, 2022 | 12:53h | UTCFDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT
Cohort Study: Effectiveness of Pfizer, Moderna, and AstraZeneca vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting.
1 Jul, 2022 | 11:37h | UTC
Commentary on Twitter
🎉 Read our latest research article comparing the effectiveness of three #COVID vaccines against severe COVID outcomes. ▶️ https://t.co/uaQNgnDrrV#BMJMedicine #MedTwitter #openaccess pic.twitter.com/4oeG5d0j80
— BMJMedicine (@BMJMedicine) June 16, 2022
RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.
29 Jun, 2022 | 12:10h | UTCNews Releases:
Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London
Commentaries:
Commentary on Twitter
NEW Research—2-week interruption of methotrexate treatment for people w/ immune-mediated inflammatory diseases = enhanced boosting of antibody responses after #COVID19 vaccination
From Prof Abhishek Abhishek & colleagues https://t.co/y14pUEaB5X pic.twitter.com/pLvaXjJzoz
— The Lancet Respiratory Medicine (@LancetRespirMed) June 28, 2022
An analysis of SARS-CoV-2 vaccine reactogenicity: variation by type, dose, and history, severity, and recency of prior SARS-CoV-2 infection.
29 Jun, 2022 | 11:52h | UTC
Cohort Study: Association of receipt of the fourth BNT162b2 dose with omicron infection and COVID-19 hospitalizations among residents of long-term care facilities.
28 Jun, 2022 | 11:08h | UTCCommentary: Fourth Dose of BNT162b2 Prevents Severe COVID-19 in Nursing Home Residents – HealthDay
Commentary on Twitter
Cohort study found that vaccination with a fourth BNT162b2 dose vs 3 doses given 4 months or earlier, was associated with lower risk of hospitalizations by 64-67% and deaths by 72%, among residents of long-term care facilities during massive Omicron surge. https://t.co/LTZ4umgSDh
— JAMA Internal Medicine (@JAMAInternalMed) June 23, 2022
Epidemiology of myocarditis and pericarditis following mRNA vaccination by vaccine product, schedule, and interdose interval among adolescents and adults in Ontario, Canada.
27 Jun, 2022 | 11:51h | UTCCommentary: Young Men’s Myocarditis Risk 5 Times Higher With Moderna vs Pfizer Vax — But Canadian study finds that 8-week interval before second dose attenuates some of the risk – MedPage Today (free registration required)
[Press Release – not published yet]: RCT: Sanofi-GSK report its vaccine targeted against ancestral and Beta strains had an overall efficacy of 72% against the Omicron variant.
27 Jun, 2022 | 11:52h | UTCPress Release: Sanofi-GSK first to report a successful efficacy study against Omicron with COVID-19 Beta-containing vaccine – Sanofi
Commentaries: Bivalent COVID Vax Gets Phase III Win Against Omicron, Companies Say — Sanofi, GSK boast of 72% efficacy against Omicron variant – MedPage Today (free registration required)
Phase 2a RCT: Vaccine efficacy in adults in a respiratory syncytial virus challenge study.
27 Jun, 2022 | 11:21h | UTCVaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study -New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Challenge Study Shows Efficacy of RSV Vaccine in Healthy Adults – HealthDay
Commentary on Twitter
A human challenge model was used to assess the safety and immunogenicity of an RSV prefusion F protein-based vaccine against RSV infection. The vaccine construct has advanced to further clinical testing.https://t.co/KKfqzCyyGF pic.twitter.com/H7i7F8KLmv
— NEJM (@NEJM) June 22, 2022
EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.
24 Jun, 2022 | 11:17h | UTC