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Vaccines

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

26 Jul, 2021 | 02:54h | UTC

Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses – JAMA

Commentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required)

Related:

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentary on Twitter

 


WHO: Vaccine inequity undermining global economic recovery.

23 Jul, 2021 | 10:53h | UTC

News release: Vaccine inequity undermining global economic recovery – World Health Organization

Dashboard: Global Dashboard for Vaccine Equity

Commentaries: Urgent need for COVID-19 vaccine equity – University of Oxford AND COVID-19 Vaccine Inequity Undermines Global Economic Recovery  – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 


Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

22 Jul, 2021 | 11:16h | UTC

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant – New England Journal of Medicine

Commentaries: Study Finds Pfizer And AstraZeneca Vaccines Effective Against The Delta Variant — As Long As You Get Both Doses – Forbes AND Pfizer’s COVID-19 vaccine works very well against the Delta variant — but only after 2 doses – Insider

Related: [Preprint] 2 doses of Covid vaccines (Pfizer-BioNTech or Oxford-AstraZeneca) highly effective against hospitalization from Delta variant. AND Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. AND Should I get my second AstraZeneca dose? Yes, it almost doubles your protection against Delta.

 

Commentary on Twitter

 


Should children get COVID vaccines? What the science says.

22 Jul, 2021 | 11:06h | UTC

Should children get COVID vaccines? What the science says – Nature

 


Opinion | The benefits of a COVID vaccine far outweigh the small risk of treatable heart inflammation.

22 Jul, 2021 | 10:57h | UTC

The benefits of a COVID vaccine far outweigh the small risk of treatable heart inflammation – The Conversation

 


Analysis finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis.

22 Jul, 2021 | 11:05h | UTC

News release: Study finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis – American Heart Association

Original study: Myocarditis with COVID-19 mRNA Vaccines – Circulation

Commentary: Myocarditis and COVID-19 Vaccines: New Review Tackles Knowns, Unknowns – TCTMD

 

Commentary on Twitter

 


WHO and UNICEF warn of a decline in vaccinations during COVID-19.

20 Jul, 2021 | 10:27h | UTC

WHO and UNICEF warn of a decline in vaccinations during COVID-19 – World Health Organization

See also: COVID-19 pandemic leads to major backsliding on childhood vaccinations, new WHO, UNICEF data shows – World Health Organization

Related: Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.

 


Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020.

20 Jul, 2021 | 10:04h | UTC

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 – The Lancet

Related: Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.

 


CDC warns Covid-19 vaccines might not protect people who are immunocompromised – “CDC is looking into ongoing research exploring the possibility that immunocompromised could benefit from an additional dose”.

18 Jul, 2021 | 23:38h | UTC

CDC warns Covid-19 vaccines might not protect people who are immunocompromised – CNN

 


Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.

15 Jul, 2021 | 09:24h | UTC

Millions of children worldwide missed routine vaccinations during the pandemic, study suggests – CNN

Original study: Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study – The Lancet

Invited Commentary: Disruptions to childhood immunisation due to the COVID-19 pandemic – The Lancet

 


Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

14 Jul, 2021 | 11:20h | UTC

Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women – JAMA

Commentary: Pfizer COVID vaccine shows 78% efficacy in pregnancy – CIDRAP

 


One COVID vaccine dose yields good protection in elderly, 2 studies find.

14 Jul, 2021 | 11:15h | UTC

One COVID vaccine dose yields good protection in elderly, 2 studies find – CIDRAP

Original study 1: Vaccine effectiveness of the first dose of ChAdOx1 nCoV-19 and BNT162b2 against SARS-CoV-2 infection in residents of long-term care facilities in England (VIVALDI): a prospective cohort study – The Lancet Infectious Diseases

Original Study 2: Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study – The Lancet Infectious Diseases

 

Commentary on Twitter (thread – click for more)

 


Extremely rare cases of Guillain-Barré reported with Johnson & Johnson vaccine for Covid-19.

13 Jul, 2021 | 09:48h | UTC

J&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT

See also: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR AND F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times

 


Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

9 Jul, 2021 | 10:16h | UTC

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization – Nature

Commentaries: Study highlights need for full Covid vaccination to protect against Delta variant – STAT AND How does the Delta variant dodge the immune system? Scientists find clues. – The New York Times

 

Commentary on Twitter (thread – click for more)

 


Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.

8 Jul, 2021 | 09:22h | UTC

Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine

Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.

 

Commentary on Twitter

 


Mounting evidence suggests Sputnik COVID vaccine is safe and effective.

8 Jul, 2021 | 09:14h | UTC

Mounting evidence suggests Sputnik COVID vaccine is safe and effective – Nature

Related: Russia Pushes Ahead with Open License Approach to Sputnik V – Despite WHO Concerns Over Manufacturing Practices – Health Policy Watch

 


Study Commentary: Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization.

8 Jul, 2021 | 08:54h | UTC

Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization – NEJM Journal Watch

Original study: Impact of the 13-valent pneumococcal conjugate vaccine on acute otitis media and acute sinusitis epidemiology in British Columbia, Canada – Journal of Antimicrobial Chemotherapy

 


RCOG Guidance: Coronavirus (COVID-19) Vaccination in Pregnancy.

7 Jul, 2021 | 08:53h | UTC

Coronavirus (COVID-19) Vaccination in Pregnancy – Royal College of Obstetricians & Gynaecologists

See also: Resources and FAQs – Royal College of Obstetricians & Gynaecologists

 

Commentary on Twitter

 


Opinion | Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality.

6 Jul, 2021 | 10:18h | UTC

Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality – Nature Medicine

 

Commentary on Twitter

 


Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.

5 Jul, 2021 | 02:39h | UTC

Joint COVAX Statement on the Equal Recognition of Vaccines – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


Opinion | Covid is a greater risk to young people than the vaccines.

5 Jul, 2021 | 02:34h | UTC

Covid Is a Greater Risk to Young People Than the Vaccines – The New York Times

Counterpoint: Weighing myocarditis cases, ACIP failed to balance the harms vs benefits of 2nd doses – by Wesley Pegden AND Vaccine-Induced Myocarditis Concerns Demand Respect, Not Absolutism – Medscape (free registration required)

 

Commentary on Twitter

 


Roundup on Covid vaccines | A Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark.

5 Jul, 2021 | 02:31h | UTC

A Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark – Absolutely Maybe Blog

 

Commentary on Twitter

 


Why Covid-19 outbreaks in countries using Chinese vaccines don’t necessarily mean the shots have failed.

5 Jul, 2021 | 02:30h | UTC

Why Covid-19 outbreaks in countries using Chinese vaccines don’t necessarily mean the shots have failed – CNN

 


What are the Sinopharm and Sinovac vaccines? And how effective are they? Two experts explain.

5 Jul, 2021 | 02:28h | UTC

Related: What are the Sinopharm and Sinovac vaccines? And how effective are they? Two experts explain – The Conversation

 


Germany issues world’s strongest recommendation for mixing Covid-19 vaccines.

5 Jul, 2021 | 02:27h | UTC

Germany issues world’s strongest recommendation for mixing Covid-19 vaccines – CNN

Related: [Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

 


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