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Tropical Medicine

RCT | Paromomycin and Miltefosine combination as an alternative to treat patients with visceral leishmaniasis.

28 Sep, 2022 | 13:43h | UTC

Paromomycin and Miltefosine Combination as an Alternative to Treat Patients With Visceral Leishmaniasis in Eastern Africa: A Randomized, Controlled, Multicountry Trial – Clinical Infectious Diseases

 


Diagnosis and management of Monkeypox: a review for the emergency clinician.

26 Sep, 2022 | 12:07h | UTC

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Related:

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 


M-A | Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide.

19 Sep, 2022 | 12:36h | UTC

Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data – BMC Medicine

 


Systematic Review | Adding rapid diagnostic tests to community‐based programs for treating malaria.

13 Sep, 2022 | 12:57h | UTC

Adding rapid diagnostic tests to community‐based programmes for treating malaria – Cochrane Library

Summary: Does adding rapid diagnostic tests to community-based malaria programmes improve the treatment of people with malaria or fever? – Cochrane Library

 


Monkeypox: disease epidemiology, host immunity and clinical interventions.

11 Sep, 2022 | 22:54h | UTC

Monkeypox: disease epidemiology, host immunity and clinical interventions – Nature Reviews Immunology

 

Commentary on Twitter

 


Study raises concerns about the effectiveness of the monkeypox vaccine.

6 Sep, 2022 | 14:39h | UTC

Study raises concerns about the effectiveness of the monkeypox vaccine – STAT

Original Study (Preprint): Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals – medRxiv

 


Reports of asymptomatic monkeypox suggest that, at the very least, some infections go unnoticed.

1 Sep, 2022 | 11:54h | UTC

Reports of Asymptomatic Monkeypox Suggest That, at the Very Least, Some Infections Go Unnoticed – JAMA

 


Monkeypox: a clinical update for pediatricians.

24 Aug, 2022 | 14:19h | UTC

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Related:

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 


Cluster RCT | Effect of biannual mass azithromycin distributions to preschool-aged children on trachoma prevalence.

24 Aug, 2022 | 13:55h | UTC

Effect of Biannual Mass Azithromycin Distributions to Preschool-Aged Children on Trachoma Prevalence in Niger: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


WHO makes new recommendations for Ebola treatments, calls for improved access.

22 Aug, 2022 | 12:26h | UTC

News Release: WHO makes new recommendations for Ebola treatments, calls for improved access – World Health Organization

Guideline: Therapeutics for Ebola virus disease – World Health Organization

Commentary: WHO Recommends Two Monoclonal Antibodies for Ebola Treatment; Calls to Expand Access in Developing Countries – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 


Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

18 Aug, 2022 | 12:56h | UTC

Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study – The Lancet

Commentaries:

Treating monkeypox like an STI may help control the outbreak, but stigma is a danger – The Conversation

Anal and oral sex spread monkeypox. Let’s talk about it. – Vox

Related:

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

17 Aug, 2022 | 14:37h | UTC

Epidemiologic and Clinical Characteristics of Monkeypox Cases — United States, May 17–July 22, 2022 – Morbidity and Mortality Weekly Report

Commentaries:

CDC releases interim monkeypox guidance, reports epidemiologic and clinical characteristics – ACP Internist

Global experts race to understand rare cases when monkeypox leads to death – CNN

Related:

Update on the Monkeypox Outbreak – JAMA

Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


CDC interim guidance for prevention and treatment of Monkeypox in persons with HIV infection.

17 Aug, 2022 | 14:36h | UTC

Interim Guidance for Prevention and Treatment of Monkeypox in Persons with HIV Infection — United States, August 2022 – Morbidity and Mortality Weekly Report

 


Update on the Monkeypox outbreak.

15 Aug, 2022 | 12:24h | UTC

Update on the Monkeypox Outbreak – JAMA

Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

Related:

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 


RCT | Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi.

15 Aug, 2022 | 11:55h | UTC

Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial – The Lancet Global Health

Commentaries:

Typhoid conjugate vaccine: are we heading towards the elimination of typhoid in endemic countries? – The Lancet Global Health

New TCV data from Malawi highlight longer-term immune response – Coalition Against Typhoid

Related:

Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children – New England Journal of Medicine

Cluster RCT: Vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh conferred 85% total protection.

Randomized Trial: Efficacy Analysis of a Typhoid Conjugate Vaccine

 


Phase 1 Study | Low-dose subcutaneous or intravenous monoclonal antibody can prevent malaria in a human challenge model.

4 Aug, 2022 | 14:45h | UTC

Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria – New England Journal of Medicine

Editorial: Monoclonal Antibodies for Malaria – New England Journal of Medicine

 


Antivirals with activity against Monkeypox: a clinically oriented review.

3 Aug, 2022 | 14:26h | UTC

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Related:

WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 


Review | Diagnosis, treatment, and prevention of Malaria in the US.

3 Aug, 2022 | 14:27h | UTC

Diagnosis, Treatment, and Prevention of Malaria in the US: A Review – JAMA (free for a limited period)

Audio Clinical Review: Diagnosis, Treatment, and Prevention of Malaria in the US – JAMA

 


WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox.

1 Aug, 2022 | 12:24h | UTC

WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN

See also: WHO recommends gay and bisexual men limit sexual partners to reduce the spread of monkeypox – CNBC

Related:

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


Monkeypox | A contemporary review for healthcare professionals.

1 Aug, 2022 | 12:20h | UTC

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

Related:

WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

 


Clinical features and novel presentations of human monkeypox in a central London center during the 2022 outbreak: descriptive case series.

1 Aug, 2022 | 12:22h | UTC

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

Related:

WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


Monkeypox virus infection in humans across 16 countries — April–June 2022.

25 Jul, 2022 | 13:09h | UTC

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Commentary: Largest monkeypox study to date highlights new symptoms – CIDRAP

Related: WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

 

Commentary on Twitter

 


WHO declares global public health emergency over Monkeypox virus outbreak.

25 Jul, 2022 | 13:11h | UTC

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Related: Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

 


Case Series | Chapare hemorrhagic fever and virus detection in rodents in Bolivia in 2019.

22 Jul, 2022 | 11:16h | UTC

Chapare Hemorrhagic Fever and Virus Detection in Rodents in Bolivia in 2019 – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


With monkeypox spreading globally, many experts believe the virus can’t be contained.

21 Jul, 2022 | 13:12h | UTC

With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT

Related:

A Primer on Monkeypox Virus for Obstetrician–Gynecologists: Diagnosis, Prevention, and Treatment – Obstetrics & Gynecology

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


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