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Infectious Diseases (all articles)

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.

5 Dec, 2021 | 23:51h | UTC

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed – STAT

Original report: Tshwane District Omicron Variant Patient Profile – Early Features

 


Fauci says early reports encouraging about omicron variant – “Thus far, it does not look like there’s a great degree of severity to it”.

5 Dec, 2021 | 23:47h | UTC

Fauci says Omicron variant doesn’t look severe, but ‘got to be careful’ – Associated Press

 


WHO has no reports yet of Omicron Covid deaths.

5 Dec, 2021 | 23:48h | UTC

WHO has no reports yet of Omicron Covid deaths – MedicalXpress

 

Commentary on Twitter

 


Editorial: Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) – highlights Africa’s research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts.

5 Dec, 2021 | 23:46h | UTC

Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) – highlights Africa’s research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts – International Journal of Infectious Diseases

 


Pictorial Review: Spinal disorders mimicking infection.

5 Dec, 2021 | 23:10h | UTC

Spinal disorders mimicking infection – Insights into Imaging

 


[Preprint] Preliminary data points to increased risk of SARS-CoV-2 reinfection associated with the emergence of Omicron variant in South Africa.

3 Dec, 2021 | 10:29h | UTC

Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa – medRxiv

Commentaries:

Global Omicron COVID cases rise as evidence for immune escape grows – CIDRAP

Omicron seems to carry higher Covid reinfection risk, says South Africa – The Guardian

Reinfections three times more likely with Omicron: S. African research – MedicalXpress

 

Commentary from the author on Twitter (thread – click for more)

 


Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic.

3 Dec, 2021 | 10:28h | UTC

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic – The Lancet

 

Commentary on Twitter

 


Podcast: The Omicron Variant of SARS-CoV-2.

3 Dec, 2021 | 10:21h | UTC

The Omicron Variant of SARS-CoV-2 – New England Journal of Medicine

 


Collection: What can the world learn from China’s response to covid-19?

3 Dec, 2021 | 10:24h | UTC

Homepage: China’s response to Covid-19 – The BMJ

Editorial: What can the world learn from China’s response to covid-19?

Rapid and sustained containment of covid-19 is achievable and worthwhile: implications for pandemic response

Importance of public health tools in emerging infectious diseases

Vaccination strategy and challenges for consolidating successful containment of covid-19 with population immunity in China

Non-pharmaceutical interventions during the roll out of covid-19 vaccines

Use of contact tracing, isolation, and mass testing to control transmission of covid-19 in China

Role of asymptomatic and pre-symptomatic infections in covid-19 pandemic

Effectiveness of 14 day quarantine strategy: Chinese experience of prevention and control

Cold chain logistics: a possible mode of SARS-CoV-2 transmission?

Better modelling of infectious diseases: lessons from covid-19 in China

Learning for the next pandemic: the Wuhan experience of managing critically ill people

 


Interactive Infographic: Visualizing SARS-CoV-2 transmission routes and mitigations.

3 Dec, 2021 | 10:26h | UTC

Visualising SARS-CoV-2 transmission routes and mitigations – The BMJ

Commentary: New interactive graphic tool illustrates SARS-CoV-2 transmission routes and mitigations – News Medical

 

Commentary on Twitter

 


Omicron is supercharging the COVID vaccine booster debate – “The data are growing that booster jabs enhance protection — but their durability, impact and ability to quash the new variant are unknown”.

3 Dec, 2021 | 10:19h | UTC

Omicron is supercharging the COVID vaccine booster debate – Nature

 


Omicron-variant border bans ignore the evidence, say scientists – “Researchers say travel restrictions in response to the newly detected coronavirus variant come too late and could even slow studies of Omicron”.

3 Dec, 2021 | 10:20h | UTC

Omicron-variant border bans ignore the evidence, say scientists – Nature

 


How bad is Omicron? What scientists know so far.

3 Dec, 2021 | 10:18h | UTC

How bad is Omicron? What scientists know so far – Nature

 


Opinion | Omg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant.

3 Dec, 2021 | 10:16h | UTC

Omg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant – The Conversation

 


Review: Interventions to optimize antimicrobial stewardship.

3 Dec, 2021 | 10:11h | UTC

Interventions to optimize antimicrobial stewardship – Antimicrobial Stewardship & Healthcare Epidemiology

 


Germany on Thursday announced a nationwide lockdown for the unvaccinated.

3 Dec, 2021 | 10:14h | UTC

Germany locks down unvaccinated people, as leaders plan to make shots compulsory – CNN

See also: Germany locks unvaccinated out of public life; mandate looms – Associated Press

 


The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – “So far, panic about the new Covid variant has outpaced actual information. Here’s what scientists around the world are trying to uncover”.

2 Dec, 2021 | 10:08h | UTC

The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – Wired

See also the latest articles on the subject:

Where did ‘weird’ Omicron come from? – Science

We can prevail over Omicron. We just need to use the tools we have – The Guardian

How South African Researchers Identified the Omicron Variant of COVID – The New Yorker

The omicron variant has been found in 23 countries – NPR

These countries have found cases of the Omicron Covid-19 variant so far – CNN

Scientists say it will take weeks to tell how dangerous Omicron really is. Here’s why – CNN

Coronavirus variants: Here’s what we know – CNN

To catch variants like omicron, the world needs to sequence way more virus genes – Vox

Omicron’s Best- and Worst-Case Scenarios – The Atlantic

Africa: tackle HIV and COVID-19 together – Nature

Omicron Travel Bans Violate International Health Rules and Decimate Southern Africa’s Fragile Tourism Industry – Health Policy Watch

The mystery of where omicron came from — and why it matters – NPR

A reason for optimism on Omicron: Our immune systems are not blank slates – STAT

Omicron – Science-Based Medicine

Covid: Omicron may require ‘very stringent response’, say Sage scientists – BBC

WHO warns against Omicron travel bans as nations shut borders – MedicalXpress

Israeli doctor believes he caught Omicron variant of Covid in London – The Guardian

First case of Omicron coronavirus variant identified in the U.S. – STAT

 


Retrospective Cohort Study: Except for Rituximab, most immunosuppressive medicines were not associated with increased risk of mechanical ventilation or death in patients hospitalized with Covid-19.

2 Dec, 2021 | 10:07h | UTC

Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative – The Lancet Rheumatology

Commentaries:

What does endemic COVID-19 mean for the future of rituximab? – The Lancet Rheumatology

Outcomes for hospitalized COVID-19 patients taking immunosuppressive medications similar to non-immunosuppressed patients, study finds – Johns Hopkins University Bloomberg School of Public Health

Study: Immune-suppressed not at higher risk of poor COVID outcomes – CIDRAP

 

Commentary on Twitter

 


AAP Clinical Report | Tuberculosis Infection in Children and Adolescents.

2 Dec, 2021 | 09:58h | UTC

Tuberculosis Infection in Children and Adolescents: Testing and Treatment – Pediatrics

 


Systematic Review: Models of COVID-19 vaccine prioritization – “for countries seeking to minimize deaths, prioritizing vaccination of senior adults was the optimal strategy and for countries seeking to minimize cases the young were prioritized”.

2 Dec, 2021 | 10:02h | UTC

Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review – BMC Medicine

 


World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response.

2 Dec, 2021 | 10:03h | UTC

World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response – World Health Organization

Commentary: Standing Ovation as WHO Member States Commit to Negotiating New Pandemic Accord – Health Policy Watch

 


Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.

2 Dec, 2021 | 10:04h | UTC

Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence – Drugs

Related:

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 


Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic.

1 Dec, 2021 | 09:52h | UTC

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic – Critical Care

 


WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529).

1 Dec, 2021 | 10:02h | UTC

WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529) – World Health Organization

Commentary: Over-60s, vulnerable should postpone travel due to Omicron: WHO – MedicalXpress

See also the latest articles on the subject:

Will omicron – the new coronavirus variant of concern – be more contagious than delta? A virus evolution expert explains what researchers know and what they don’t – The Conversation

WHO pleads for ‘rational’ Omicron response – MedicalXpress

Omicron: WHO warns of ‘high infection risk’ around globe – BBC

Video: Why Omicron is the most worrying Covid variant yet – video explainer – The Guardian

Doctors hope Omicron causes milder cases of Covid — but it’s still too early to say – STAT

Doctor: Many South Africans ill in surge have mild symptoms – Associated Press

New Findings Show the Omicron Variant Spread Widely At a Faster Pace Than Initially Thought – TIME

Why some researchers think the omicron variant could be the most infectious one yet – NPR

Omicron Covid variant ‘present in Europe at least 10 days ago’ – The Guardian

Netherlands says Omicron variant was already in country earlier than previously thought – CNN

Netherlands detections hint at earlier Omicron spread – CIDRAP

Epidemiologist awaits clearer picture on omicron – Harvard University

Pfizer research head envisions a sprint to develop Omicron vaccine, if it’s needed – STAT

Omicron COVID variant was in Europe before South African scientists detected and flagged it to the world – CBS News

Moderna boss predicts current vaccines may be less effective against Omicron – The Guardian

Wealthy nations starved the developing world of vaccines. Omicron shows the cost of this greed – The Conversation

Travel restrictions by country following the Omicron variant outbreak – CNN

 


FDA panel narrowly recommends authorization of first antiviral pill to treat COVID.

1 Dec, 2021 | 09:56h | UTC

FDA panel narrowly recommends authorization of first antiviral pill to treat COVID – STAT

See also: An FDA panel supports Merck COVID drug in mixed vote – NPR

Related:

[Press release – not published yet] Merck’s new Covid-19 pill Molnupiravir updated data shows reduced efficacy (30%) for preventing hospitalization and death compared to initial results (50%). Absolute risk reduction of hospitalization and death fell from 7% to 3%.

8 lingering questions about the new Covid pills from Merck and Pfizer.

COVID antiviral pills: what scientists still want to know – “Drugs like Molnupiravir and Paxlovid could change the course of the pandemic if clinical trial results hold up in the real world”.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

 


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