Infectious Diseases (all articles)
CDC Report: Acute hepatitis and adenovirus infection among children.
2 May, 2022 | 00:46h | UTCCommentaries:
CDC releases new clinical details in cases of unusual hepatitis in children – CNN
CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News
Related:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentaries on Twitter
Report from Alabama of acute hepatitis & adenovirus infection in young kids, Oct 21-Feb 22. 9 cases, all had adenovirus, 5/5 tested +ve for Adenovirus type 41. No epi links found. All under 6 yrs of age, immunocompetent, & no significant comorbidities. https://t.co/DcgcfN3KHo
— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) April 29, 2022
New report from @CDCMMWR on the 9 episodes of severe acute hepatitis in children from Alabama
All 9 positive for Adenovirus on whole blood PCR (all 5 samples sequences were type 41)
None PCR positive for #SARSCoV2
HT @tonisoriano66 https://t.co/h9LmHeVHEf
— Alasdair Munro (@apsmunro) April 29, 2022
ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.
2 May, 2022 | 00:44h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Pfizer says COVID treatment Paxlovid fails to prevent infection of household members.
2 May, 2022 | 00:43h | UTCPfizer says COVID treatment Paxlovid fails to prevent infection of household members – Reuters
Commentary on Twitter
Pfizer Inc on Friday said a large trial found that its COVID-19 oral antiviral treatment Paxlovid was not effective at preventing coronavirus infection in people living with someone who had been exposed to the virus. https://t.co/95zphEYaxc
— Reuters Health (@Reuters_Health) April 29, 2022
Systematic Review: Negative pressure wound therapy for surgical wounds healing by primary closure.
1 May, 2022 | 23:32h | UTCNegative pressure wound therapy for surgical wounds healing by primary closure – Cochrane Library
Summary: Dressings that use negative pressure for closed surgical wounds – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1520732015972208647
Review: Anti-tuberculosis treatment strategies and drug development: challenges and priorities.
1 May, 2022 | 23:23h | UTCAnti-tuberculosis treatment strategies and drug development: challenges and priorities – Nature Reviews Microbiology (if the link is paywalled, try this one)
News Release: A major update on global tuberculosis fight – Hackensack Meridian Health
Commentary on Twitter
Anti-tuberculosis treatment strategies and drug development: challenges and prioritieshttps://t.co/nZlcEwTDLP
In this Review, Dartois and Rubin explore challenges and priorities for anti-tuberculosis treatment strategies and drug development.@vdartois1 pic.twitter.com/t6RQoaFb8C
— Nature Reviews Microbiology (@NatureRevMicro) April 27, 2022
M-A: Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy.
1 May, 2022 | 23:09h | UTC
RCT: Extended vs. standard antibiotic course duration in children below 5 years of age hospitalized with community-acquired pneumonia in high-risk settings.
29 Apr, 2022 | 11:16h | UTCRelated:
Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics
Commentary on Twitter
15th RCT of short course therapy for CAP just published, this one another peds study (3 mo to <5 yr). 5-6 d vs. 14 days. Guess what the outcome was??? Updated tables will be tweeted out soon!@ABsteward @DoctorRachael @medrants https://t.co/br4WAEXAzJ
— Brad Spellberg (@BradSpellberg) April 28, 2022
Review: Understanding vaccine safety and the roles of the FDA and the CDC.
29 Apr, 2022 | 11:13h | UTCUnderstanding Vaccine Safety and the Roles of the FDA and the CDC – New England Journal of Medicine
Commentary on Twitter
Development and public acceptance of vaccines are crucial for disease control. Cody Meissner, M.D., reviews the process of evaluating vaccine safety and efficacy and factors that advisory bodies consider in making recommendations. https://t.co/ITqpGthoac pic.twitter.com/HTkyAaWvDO
— NEJM (@NEJM) April 28, 2022
RCT: BCG vaccine is not effective in reducing healthcare worker absenteeism in COVID-19 pandemic.
29 Apr, 2022 | 11:05h | UTC
Commentary on Twitter
BCG-CORONA RCT💥 @CMIJournal @MarcBonten
BCG-vaccination of health care worker exposed to #COVID19 patients did NOT reduce unplanned absenteeism nor documented COVID-19 #IDTwitter #MedEd #TwitteRx #MedTwitter https://t.co/yqnpmuy5Y8— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 28, 2022
Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.
29 Apr, 2022 | 11:07h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
29 Apr, 2022 | 10:51h | UTC
Commentary on Twitter
🆕💥Review Article @ASHE_Journal
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them #IDTwitter #medtwitter #TwitteRx #MedEd https://t.co/ToPLQXtC4r pic.twitter.com/pZQWWb3ZSx— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 28, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
M-A: Household secondary attack rates of SARS-CoV-2 by variant and vaccination status.
29 Apr, 2022 | 10:57h | UTC
Commentary on Twitter
This systematic review & meta-analysis found household #SARSCoV2 secondary attack rates increased over time and were higher for variants than prior reported estimates. Vaccination was associated with reduced transmission (more for Alpha vs Delta & Omicron) https://t.co/6vwW0u3vY7
— JAMA Network Open (@JAMANetworkOpen) April 28, 2022
Expert Consensus: Topical treatment of recurrent vulvovaginal candidiasis.
29 Apr, 2022 | 10:46h | UTC
Covid-19: What is the evidence for the antiviral Paxlovid?
28 Apr, 2022 | 10:58h | UTCCovid-19: What is the evidence for the antiviral Paxlovid? – The BMJ
Related:
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
A living WHO guideline on drugs for covid-19 – The BMJ
Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis.
28 Apr, 2022 | 10:56h | UTC
Commentary on Twitter
https://twitter.com/bmj_latest/status/1519430941759918080
Experts fear U.S. may default to annual Covid boosters without sufficient data.
28 Apr, 2022 | 10:51h | UTCExperts fear U.S. may default to annual Covid boosters without sufficient data – STAT
Commentary on Twitter
Vaccine experts are concerned the U.S. may be sleepwalking into a policy of recommending annual Covid-19 vaccine boosters — without having generated the evidence to show they are actually needed. https://t.co/3TiNZvP0HY
— STAT (@statnews) April 26, 2022
Public health impact of covid-19 vaccines in the US: observational study.
28 Apr, 2022 | 10:54h | UTCPublic health impact of covid-19 vaccines in the US: observational study – The BMJ
Editorial: The benefits of large scale covid-19 vaccination – The BMJ
Commentary on Twitter (thread – click for more)
Paper and accompanying editorial https://t.co/uwqY0PqYsE
"Many more lives could have been saved……
this new study is another confidence booster for covid-19 vaccines." pic.twitter.com/o4FygrAX8T— Eric Topol (@EricTopol) April 27, 2022
Phase 2b trial: Prefusion F protein–based respiratory syncytial virus immunization in pregnancy.
28 Apr, 2022 | 08:09h | UTCPrefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: RSV Prefusion F Protein-Based Immunization Studied in Pregnancy – HealthDay
Commentary on Twitter
In pregnant women, RSVpreF vaccine elicited neutralizing antibody responses with efficient transplacental transfer and without evident safety concerns. https://t.co/r8oktZmBZQ pic.twitter.com/UE7ffxYJW6
— NEJM (@NEJM) April 27, 2022
M-A: Risk factors for acquired Stenotrophomonas maltophilia pneumonia in intensive care unit.
28 Apr, 2022 | 08:01h | UTC
Clinical Review: Diagnosis and management of covid-19 in pregnancy.
27 Apr, 2022 | 08:13h | UTCDiagnosis and management of covid-19 in pregnancy – The BMJ
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
Cohort Study: Incidence of Guillain-Barré syndrome after Covid-19 vaccination in the vaccine safety datalink.
27 Apr, 2022 | 08:03h | UTC
Commentary on Twitter
This cohort study of #COVID19 vaccine safety surveillance in the US Vaccine Safety Datalink found a small elevated risk of Guillain-Barré syndrome after Janssen/J&J vaccine but not after mRNA COVID-19 vaccines. @KPDOR https://t.co/TTya5BDqeV
— JAMA Network Open (@JAMANetworkOpen) April 26, 2022
Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views.
27 Apr, 2022 | 07:52h | UTC
Review: Use of antimicrobials for bloodstream infections in the intensive care unit.
27 Apr, 2022 | 01:34h | UTC
Covid-19: Only a quarter of patients admitted to hospital feel fully recovered after a year, study finds.
26 Apr, 2022 | 08:45h | UTCInvited Commentary: Long COVID: systemic inflammation and obesity as therapeutic targets – The Lancet Respiratory Medicine
Commentary on Twitter (thread – click for more)
PHOSP-COVID study:
– 232 (29%) of 804 pts fully recovered at 1y
– Female sex, obesity, & IMV = less likely to feel fully recovered
– inflamm mediators📈in those w/ most severe physical, mental health, & cognitive impairmentsRead it here: https://t.co/rVZuVDo4xl
— The Lancet Respiratory Medicine (@LancetRespirMed) April 25, 2022


