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Infectious Diseases (all articles)

WHO Report: 14.9 million excess deaths associated with the COVID-19 pandemic in 2020 and 2021.

9 May, 2022 | 02:14h | UTC

News Release: 14.9 million excess deaths associated with the COVID-19 pandemic in 2020 and 2021 – World Health Organization

Original Report: Global excess deaths associated with COVID-19, January 2020 – December 2021 – World Health Organization

Commentaries:

Covid-19: True global death toll from pandemic is almost 15 million, says WHO – The BMJ

WHO: Nearly 15 million died as a result of Covid-19 in first two years of pandemic – STAT

WHO notes 15 million excess deaths over 2 COVID years – CIDRAP

Related:

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21 – The Lancet

“Excess deaths” is the best metric for tracking the pandemic – The BMJ

The pandemic’s true death toll: millions more than official counts – Nature

Effects of covid-19 pandemic on life expectancy and premature mortality in 2020: time series analysis in 37 countries – The BMJ

Under-reporting of deaths limits our understanding of true burden of covid-19 – The BMJ

Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries – International Journal of Epidemiology

Just How Do Deaths Due to COVID-19 Stack Up? – Think Global Health

 

Commentary on Twitter (thread – click for more)

 


Studies show promise for 2 new COVID vaccine platforms.

9 May, 2022 | 02:12h | UTC

Commentary: Studies show promise for 2 new COVID vaccine platforms – CIDRAP

Study 1: Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine – New England Journal of Medicine

Study 2: Efficacy and Safety of the RBD-Dimer–Based Covid-19 Vaccine ZF2001 in Adults – New England Journal of Medicine

Editorial: Does the World Still Need New Covid-19 Vaccines?

 

Commentaries on Twitter

 


Systematic Review: Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings.

9 May, 2022 | 02:09h | UTC

Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings – Cochrane Library

Summary: Interventions to reduce the risk of coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) infection among workers outside healthcare settings – Cochrane Library

 


Clinical challenges treating Stenotrophomonas maltophilia infections: an update.

9 May, 2022 | 01:32h | UTC

Clinical challenges treating Stenotrophomonas maltophilia infections: an update – JAC-Antimicrobial Resistance

Related:

Overcoming Stenotrophomonas maltophilia Resistance for a More Rational Therapeutic Approach – Open Forum Infectious Diseases

Risk Factors for Acquired Stenotrophomonas maltophilia Pneumonia in Intensive Care Unit: A Systematic Review and Meta-Analysis – Frontiers in Medicine

Trimethoprim-Sulfamethoxazole versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 U.S. Hospitals – Open Forum Infectious Diseases

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections – Clinical Infectious Diseases

 


Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids.

9 May, 2022 | 01:23h | UTC

Commentary: Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids – CIDRAP

Original Study: Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative – JAMA Peditrics

News Release: Hospitals can reduce antibiotic overuse by avoiding unnecessary blood draws in critically ill children, study shows – Johns Hopkins University School of Medicine

 

Commentary on Twitter

 


Podcast: Appendicitis Pearls.

9 May, 2022 | 01:15h | UTC

#49: Appendicitis – Tips and Tricks For When It’s the Appendix – The Cribsiders

 


M-A: Interventions for high-burden infectious diseases in children and adolescents.

9 May, 2022 | 01:12h | UTC

Interventions for High-Burden Infectious Diseases in Children and Adolescents: A Meta-analysis – Pediatrics

 


Review: SARS-CoV-2 pathogenesis.

6 May, 2022 | 11:01h | UTC

SARS-CoV-2 pathogenesis – Nature Reviews Microbiology

 

Commentary on Twitter

 


Long COVID: aiming for a consensus.

6 May, 2022 | 11:03h | UTC

Long COVID: aiming for a consensus – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


Review: Overcoming Stenotrophomonas maltophilia resistance for a more rational therapeutic approach.

6 May, 2022 | 10:31h | UTC

Overcoming Stenotrophomonas maltophilia Resistance for a More Rational Therapeutic Approach – Open Forum Infectious Diseases

 


Review: Non-invasive testing and surrogate markers in invasive fungal diseases.

6 May, 2022 | 10:29h | UTC

Non-invasive Testing and Surrogate Markers in Invasive Fungal Diseases – Open Forum Infectious Diseases

 


With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids.

5 May, 2022 | 10:59h | UTC

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Related:

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study.

5 May, 2022 | 11:02h | UTC

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study – The BMJ

 

Commentary on Twitter

 


M-A: Efficacy and effectiveness of SARS-CoV-2 vaccines.

5 May, 2022 | 10:26h | UTC

Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis – Vaccines

 


WHO calls for shorter drug course for resistant TB.

4 May, 2022 | 11:08h | UTC

WHO calls for shorter drug course for resistant TB – CIDRAP

Rapid communication: Key changes to the treatment of drug-resistant tuberculosis – World Health Organization

 


Retrospective cohort study: Treatment outcome with penicillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bacteremia.

5 May, 2022 | 09:39h | UTC

Treatment outcome with penicillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bacteraemia – A retrospective cohort study – International Journal of Antimicrobial Agents

 

Commentary on Twitter

 


Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic.

4 May, 2022 | 10:57h | UTC

Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic – STAT

 


Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection.

4 May, 2022 | 10:36h | UTC

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection – Nature Communications

 

Commentary on Twitter (thread – click for more)

https://twitter.com/JessicaLittleMD/status/1521513877242101762

 


Remdesivir and three other drugs for hospitalized patients with COVID-19: final results of the WHO Solidarity randomized trial and updated meta-analyses.

3 May, 2022 | 11:18h | UTC

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses – The Lancet

Invited Commentary: When and which patients should receive remdesivir? – The Lancet

 


RCT: Effects of an online breathing and wellbeing program for people with persistent symptoms following COVID-19.

3 May, 2022 | 11:16h | UTC

An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial – The Lancet Respiratory Medicine

Invited Commentary: Treating COVID-19-related breathlessness with novel interventions – The Lancet Respiratory Medicine

News Release: Singing techniques can improve quality of life and breathlessness after COVID-19 – Imperial College London

 

Commentary on Twitter

https://twitter.com/LancetRespirMed/status/1519572126772064256

 


Systematic Review: Telerehabilitation improves physical function and reduces dyspnea in people with COVID-19 and post-COVID-19 conditions.

3 May, 2022 | 11:05h | UTC

Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-COVID-19 conditions: a systematic review – Journal of Physiotherapy

 


Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

3 May, 2022 | 11:04h | UTC

POINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? Yes – CHEST

COUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No – CHEST

See also: Rebuttal From Dr Tritschler et al – CHEST

Related:

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

 


M-A of randomized trials: association of influenza vaccination with cardiovascular risk.

3 May, 2022 | 10:58h | UTC

Association of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


CDC reports the first case and issues recommendations for highly pathogenic avian Influenza A(H5N1) virus.

3 May, 2022 | 11:00h | UTC

Highly Pathogenic Avian Influenza A(H5N1) Virus: Recommendations for Human Health Investigations and Response – Centers for Disease Control and Prevention

See also: U.S. Case of Human Avian Influenza A(H5) Virus Reported – Centers for Disease Control and Prevention

Commentary: Alaska, Oklahoma report first avian flu outbreaks in poultry – CIDRAP

 


M-A: Risk factors for contracting invasive meningococcal disease and related mortality.

3 May, 2022 | 10:29h | UTC

Risk Factors for Contracting Invasive Meningococcal Disease and Related Mortality: A Systematic Literature Review and Meta-analysis – International Journal of Infectious Diseases

 


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