Infectious Diseases (all articles)
WHO Report: 14.9 million excess deaths associated with the COVID-19 pandemic in 2020 and 2021.
9 May, 2022 | 02:14h | UTCNews Release: 14.9 million excess deaths associated with the COVID-19 pandemic in 2020 and 2021 – World Health Organization
Original Report: Global excess deaths associated with COVID-19, January 2020 – December 2021 – World Health Organization
Commentaries:
Covid-19: True global death toll from pandemic is almost 15 million, says WHO – The BMJ
WHO: Nearly 15 million died as a result of Covid-19 in first two years of pandemic – STAT
WHO notes 15 million excess deaths over 2 COVID years – CIDRAP
Related:
“Excess deaths” is the best metric for tracking the pandemic – The BMJ
The pandemic’s true death toll: millions more than official counts – Nature
Under-reporting of deaths limits our understanding of true burden of covid-19 – The BMJ
Just How Do Deaths Due to COVID-19 Stack Up? – Think Global Health
Commentary on Twitter (thread – click for more)
The total number of deaths associated with #COVID19 worldwide from 2020-2021 may be closer to 14.9 million: New estimates by WHO & @UNDESA.
That’s 9.5 million more deaths than reported https://t.co/qDvaA6t5KZ #HealthData pic.twitter.com/ZjABJzlgiZ
— World Health Organization (WHO) (@WHO) May 5, 2022
Studies show promise for 2 new COVID vaccine platforms.
9 May, 2022 | 02:12h | UTCCommentary: Studies show promise for 2 new COVID vaccine platforms – CIDRAP
Editorial: Does the World Still Need New Covid-19 Vaccines?
Commentaries on Twitter
Efficacy of a plant-based vaccine with adjuvant was 69.5% against symptomatic #COVID19 and 78.8% against moderate-to-severe disease. https://t.co/WH54QWCBdg pic.twitter.com/BiEYpJUD7D
— NEJM (@NEJM) May 4, 2022
ZF2001 vaccine has 87% efficacy against critical or severe #COVID19 for at least 6 months after full vaccination and was safe in large cohort of adults. #IDTwitter https://t.co/wsG0AXqI4Y pic.twitter.com/45fqwVrz9a
— NEJM (@NEJM) May 4, 2022
Systematic Review: Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings.
9 May, 2022 | 02:09h | UTC
Clinical challenges treating Stenotrophomonas maltophilia infections: an update.
9 May, 2022 | 01:32h | UTCRelated:
Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids.
9 May, 2022 | 01:23h | UTCCommentary: Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids – CIDRAP
Commentary on Twitter
Results from the Bright STAR collaborative: Multi-center diagnostic stewardship found blood cultures in the PICU safely reduced overtesting and broad-spectrum antibiotic use. https://t.co/523QlbOLL2 @BrightSTAR_QI @HopkinsKids @ChildrensPhila #PICUtwitter
— JAMA Pediatrics (@JAMAPediatrics) May 2, 2022
Podcast: Appendicitis Pearls.
9 May, 2022 | 01:15h | UTC#49: Appendicitis – Tips and Tricks For When It’s the Appendix – The Cribsiders
M-A: Interventions for high-burden infectious diseases in children and adolescents.
9 May, 2022 | 01:12h | UTC
Review: SARS-CoV-2 pathogenesis.
6 May, 2022 | 11:01h | UTCSARS-CoV-2 pathogenesis – Nature Reviews Microbiology
Commentary on Twitter
A Review published in @NatureRevMicro explores recent clinical and experimental advances in understanding SARS-CoV-2 pathogenesis, interactions with host cells and the involvement of the immune system in the development of severe disease. https://t.co/GTm0BZ3ikH pic.twitter.com/jPXFU05Pwm
— Nature Portfolio (@NaturePortfolio) April 23, 2022
Long COVID: aiming for a consensus.
6 May, 2022 | 11:03h | UTCLong COVID: aiming for a consensus – The Lancet Respiratory Medicine
Commentary on Twitter
There is an urgent need for unification of terminology for the sequelae of #SARSCoV2 infection to ensure that research is directed towards and translated into interventional trials to improve outcomes
NEW Comment—#LongCOVID: aiming for a consensushttps://t.co/dZO4rBVCSY pic.twitter.com/H5ezqL0RLb
— The Lancet Respiratory Medicine (@LancetRespirMed) May 5, 2022
Review: Overcoming Stenotrophomonas maltophilia resistance for a more rational therapeutic approach.
6 May, 2022 | 10:31h | UTC
Review: Non-invasive testing and surrogate markers in invasive fungal diseases.
6 May, 2022 | 10:29h | UTC
With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids.
5 May, 2022 | 10:59h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study.
5 May, 2022 | 11:02h | UTC
Commentary on Twitter
In this international, registry based cohort study of patients with covid-19 associated acute respiratory failure, extracorporeal membrane oxygenation was associated with a reduction in mortality by 7.1% compared with conventional mechanical ventilation https://t.co/VkNFeRDQ3j
— The BMJ (@bmj_latest) May 4, 2022
M-A: Efficacy and effectiveness of SARS-CoV-2 vaccines.
5 May, 2022 | 10:26h | UTCEfficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis – Vaccines
WHO calls for shorter drug course for resistant TB.
4 May, 2022 | 11:08h | UTCWHO calls for shorter drug course for resistant TB – CIDRAP
Rapid communication: Key changes to the treatment of drug-resistant tuberculosis – World Health Organization
Retrospective cohort study: Treatment outcome with penicillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bacteremia.
5 May, 2022 | 09:39h | UTC
Commentary on Twitter
In recent years, several publications from different parts of the world have reported an increasing incidence of penicillin susceptible Staphylococcus aureus (PSSA)
🆕💥Retro study Treatment outcome with penicillin G or cloxacillin in PSSA bacteremia
SNAP?https://t.co/01TTVN4MU7— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 11, 2022
Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic.
4 May, 2022 | 10:57h | UTC
Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection.
4 May, 2022 | 10:36h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/JessicaLittleMD/status/1521513877242101762
Remdesivir and three other drugs for hospitalized patients with COVID-19: final results of the WHO Solidarity randomized trial and updated meta-analyses.
3 May, 2022 | 11:18h | UTCInvited Commentary: When and which patients should receive remdesivir? – The Lancet
RCT: Effects of an online breathing and wellbeing program for people with persistent symptoms following COVID-19.
3 May, 2022 | 11:16h | UTCInvited Commentary: Treating COVID-19-related breathlessness with novel interventions – The Lancet Respiratory Medicine
News Release: Singing techniques can improve quality of life and breathlessness after COVID-19 – Imperial College London
Commentary on Twitter
https://twitter.com/LancetRespirMed/status/1519572126772064256
Systematic Review: Telerehabilitation improves physical function and reduces dyspnea in people with COVID-19 and post-COVID-19 conditions.
3 May, 2022 | 11:05h | UTC
Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?
3 May, 2022 | 11:04h | UTCCOUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No – CHEST
See also: Rebuttal From Dr Tritschler et al – CHEST
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
M-A of randomized trials: association of influenza vaccination with cardiovascular risk.
3 May, 2022 | 10:58h | UTCAssociation of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis – JAMA Network Open
Commentary on Twitter
In this meta-analysis, seasonal flu vaccine was associated with a 34% reduced risk of major adverse cardiovascular events in 1 year, with the biggest difference in patients with recent acute coronary syndrome. @WCHResearch @PMunkCardiacCtr https://t.co/SPrXNfMQJS
— JAMA Network Open (@JAMANetworkOpen) April 29, 2022
CDC reports the first case and issues recommendations for highly pathogenic avian Influenza A(H5N1) virus.
3 May, 2022 | 11:00h | UTCSee also: U.S. Case of Human Avian Influenza A(H5) Virus Reported – Centers for Disease Control and Prevention
Commentary: Alaska, Oklahoma report first avian flu outbreaks in poultry – CIDRAP
M-A: Risk factors for contracting invasive meningococcal disease and related mortality.
3 May, 2022 | 10:29h | UTC


