Infectious Diseases (all articles)
Review: Unexplained post-acute infection syndromes.
19 May, 2022 | 10:58h | UTCUnexplained post-acute infection syndromes – Nature Medicine (if the link is paywalled, try this one)
Commentary on Twitter
A @NatureMedicine tour de force review of the unexplained post-acute infectious syndromes, which includes #LongCovid and many others https://t.co/5RnyY9l0eQ
by @jan_choutka @mhornig @VirusesImmunity pic.twitter.com/dhYeZYnM1U— Eric Topol (@EricTopol) May 18, 2022
Systematic Review: Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels.
19 May, 2022 | 10:54h | UTC
Opinion | Bill Gates and the fate of WHO.
19 May, 2022 | 10:56h | UTCOffline: Bill Gates and the fate of WHO – The Lancet
Commentary on Twitter
Offline: Bill Gates and the fate of WHO https://t.co/KKUkdFteUN An oped by @richardhorton1 in @TheLancet which he criticizes both @BillGates & @WHO on their positions to the future of pandemic responses.
— Carlos del Rio (@CarlosdelRio7) May 13, 2022
Antibiotics given shortly before cesarean birth not linked to asthma and eczema in young children.
19 May, 2022 | 10:46h | UTCNews Release: Antibiotics given shortly before cesarean birth not linked to asthma and eczema in young children – University of Birmingham
WHO: 2nd COVID booster for most vulnerable offers benefits.
18 May, 2022 | 11:10h | UTCWHO: 2nd COVID booster for most vulnerable offers benefits – World Health Organization
Scent dogs in detection of COVID-19: triple-blinded randomized trial and operational real-life screening in airport setting.
18 May, 2022 | 11:06h | UTCNews Release: Trained sniffer dogs accurately detect people infected with SARS-CoV-2 – BMJ Newsroom
Commentary: Trained scent dogs detect airline travelers with COVID-19 – CIDRAP
Management of drug interactions with Nirmatrelvir/Ritonavir (Paxlovid).
18 May, 2022 | 11:03h | UTCCommentary: IDSA offers guidance on managing drug interactions with nirmatrelvir/ritonavir – ACP Internist
Related:
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
Covid-19: What is the evidence for the antiviral Paxlovid? – The BMJ
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
A living WHO guideline on drugs for covid-19 – The BMJ
[Preprint] Effectiveness of a second COVID-19 vaccine booster on all-cause mortality in long-term care facility residents and in the oldest old: a nationwide, retrospective cohort study in Sweden.
18 May, 2022 | 11:05h | UTC
Commentary on Twitter
Confirmation of the 2nd booster protection from death in people age 80+ in Sweden, with a relative vaccine effectiveness 42% (compared w/ the 1st booster)https://t.co/Dq1x00J3Tr pic.twitter.com/fyXJPEcQzC
— Eric Topol (@EricTopol) May 17, 2022
Guideline of guidelines: management of recurrent urinary tract infections in women.
18 May, 2022 | 10:59h | UTC
Clinical update on COVID-19 for the emergency clinician: Cardiac arrest in the out-of-hospital and in-hospital settings.
17 May, 2022 | 11:05h | UTCRelated:
Cohort Study: Venous or arterial thrombosis and deaths among COVID-19 cases.
17 May, 2022 | 11:02h | UTCInvited Commentary: Risk of arterial and venous thromboses after COVID-19 – The Lancet Infectious Diseases
News Release: COVID-19’s high blood clot risk – University of Oxford
Commentary on Twitter
Clots with Covid: Multi-national report of over 900,000 people indicates propensity of risk for arterial and venous thrombi is in men, with increasing age, and association with fatalities (4-fold in non-hospitalized) https://t.co/muGnDld4Um pic.twitter.com/6bLiHPLInm
— Eric Topol (@EricTopol) May 13, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
RECOVERY Trial: Due to safety concerns, recruitment to higher dose corticosteroids closed for patients with hypoxia on no oxygen or receiving simple oxygen.
17 May, 2022 | 11:04h | UTC
Cohort Study: The risk of death or unplanned readmission after discharge from a COVID-19 hospitalization.
17 May, 2022 | 11:01h | UTCCommentary: Study: Readmission rate for COVID-19 is 11% – CIDRAP
RCT: Extended-course antibiotic prophylaxis in lower limb amputation.
17 May, 2022 | 10:50h | UTCExtended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial – British Journal of Surgery (link to abstract – $ for full-text)
Commentary on Twitter
In the May issue of BJS: Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial https://t.co/2H0TthufvZ @AmyLightnerMD @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @robhinchliffe1 @young_bjs pic.twitter.com/taSa4Caibn
— BJS (@BJSurgery) April 30, 2022
Study Commentary | Antibiotics for pediatric pneumonia: might less be enough?
17 May, 2022 | 10:39h | UTCAntibiotics for Pediatric Pneumonia: Might Less Be Enough? – Annals of Emergency Medicine
Related:
Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics
RCT: Effect of awake prone positioning on endotracheal intubation in patients with COVID-19 and acute respiratory failure.
16 May, 2022 | 02:37h | UTCRelated:
RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv
Commentary on Twitter
In this trial, in patients with acute hypoxemic respiratory failure from #COVID19, prone positioning, compared with usual care without prone positioning, did not significantly reduce endotracheal intubation at 30 days. https://t.co/1RyYRtcrYj
— JAMA (@JAMA_current) May 15, 2022
RCT: Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults.
16 May, 2022 | 02:30h | UTCComparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial – Intensive Care Medicine (free article here)
Commentary on Twitter
🧫 8 vs 15 days ABT for Pseudomonas aeruginosa VAP in adults, iDIAPASON RCT: no differences in composite or separate outcomes (90-day mortality/VAP recurrence) between short & long duration treatment.
📢 @yourICM ground-breaking release #LIVES40 #FOAMcc
🖇 https://t.co/LfoUWxCkkl pic.twitter.com/XaWkQ5R6wT— Intensive Care Medicine (@yourICM) May 13, 2022
Test-negative, case-control study: Association of prior BNT162b2 COVID-19 vaccination with symptomatic SARS-CoV-2 infection in children and adolescents during Omicron predominance.
16 May, 2022 | 02:25h | UTCEditorial: Protecting Children Against Omicron – JAMA
Commentary on Twitter (thread – click for more)
This new JAMA study is worth discussing. It found that, this winter, vax effectiveness in 12-15 yos dropped to 0% after 3-5 months & vaccinated were MORE likely to test+ at month 7. May be confounded (see🧵)
But I don't see this as good reason for boostershttps://t.co/zpkIDdZhnn pic.twitter.com/bxAIDmiR8s— Tracy Høeg, MD, PhD (@TracyBethHoeg) May 14, 2022
Hypotheses | Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens.
16 May, 2022 | 02:22h | UTCRelated:
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A solid hypothesis for the basis of the mysterious, severe acute hepatitis in children: superantigen formation from prior Covid viral reservoir in the GI tract with superimposed adenovirus infection https://t.co/1eehyQmlhi @LancetGastroHep pic.twitter.com/UqCAh3igMH
— Eric Topol (@EricTopol) May 14, 2022
Molecular diagnostics in severe pneumonia: a new dawn or false promise?
16 May, 2022 | 01:43h | UTCMolecular diagnostics in severe pneumonia: a new dawn or false promise? – Intensive Care Medicine
Commentary on Twitter
Pneumonia? no gold standard diagnosis available, likely resulting in overtreatment. Molecular diagnostics more widely available even if interpretation/use complex, requiring to take into account data/characteristics when making decisions based on these.
📎 https://t.co/mae0vxBfkF pic.twitter.com/bbkxGLEumN— Intensive Care Medicine (@yourICM) May 14, 2022
Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all populations.
16 May, 2022 | 01:41h | UTC
Review of thoracic imaging manifestations of COVID-19 and other pathologic Coronaviruses.
13 May, 2022 | 11:36h | UTC
Explaining the unexplained hepatitis in children.
13 May, 2022 | 11:39h | UTCExplaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Related:
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
New versions of Omicron are masters of immune evasion.
13 May, 2022 | 11:37h | UTCNew versions of Omicron are masters of immune evasion – Science
Commentary on Twitter
"Based on its immunological profile, it [Omicron & its subvariants] should be called SARS-3"https://t.co/zxV3T2SKIB@gretchenvogel @NewsfromScience
w/ @K_G_Andersen @Tuliodna @linfa_wang pic.twitter.com/ToKDqNGH74— Eric Topol (@EricTopol) May 12, 2022
IDSA updates guidelines on the treatment and management of patients with COVID-19.
13 May, 2022 | 11:35h | UTC