Infectious Diseases (all articles)
Indeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.
5 Jul, 2022 | 12:09h | UTCRelated:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Review | Bridging knowledge gaps in the diagnosis and management of neuropsychiatric sequelae of COVID-19.
5 Jul, 2022 | 12:07h | UTC
Commentary on Twitter
Neuropsychiatric post-acute sequelae of #COVID19 appear common but heterogeneous. Studies such as the NIH RECOVER initiative are needed to clarify neuropsychiatric PASC epidemiology, pathophysiology, mechanisms of injury and targets for intervention. https://t.co/AjwoLrZXc7
— JAMA Psychiatry (@JAMAPsych) July 1, 2022
Review | Prevention and treatment of Monkeypox.
5 Jul, 2022 | 12:05h | UTCPrevention and Treatment of Monkeypox – Drugs
RCT | Single-dose, bioadhesive Clindamycin 2% gel for bacterial vaginosis.
5 Jul, 2022 | 11:56h | UTCCommentary:
Single-Dose Clindamycin Gel Highly Effective for Bacterial Vaginosis – JAMA
Single-Dose Clindamycin Gel Highly Effective for Bacterial Vaginosis in Women – Medical Dialogues
Commentary on Twitter
FREE: Single-Dose, Bioadhesive Clindamycin 2% Gel for Bacterial Vaginosis: A Randomized Controlled Trial #obgyn https://t.co/ofIXGiFXbL pic.twitter.com/0nQigeCFP5
— The Green Journal (@greenjrnl) May 27, 2022
Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug.
4 Jul, 2022 | 12:57h | UTCBad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug – Science
See also: SARS-CoV-2 can evade Paxlovid by multiple mechanisms – News Medical
Opinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.
4 Jul, 2022 | 12:53h | UTCFDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT
Antibodies to combat viral infections: development strategies and progress.
4 Jul, 2022 | 12:51h | UTCAntibodies to combat viral infections: development strategies and progress – Nature Reviews Drug Discovery (if the link is paywalled, try this one in PMC)
Brief Review | Sudden onset hepatitis in children.
4 Jul, 2022 | 12:41h | UTCSudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)
Commentary on Twitter
NEW! In this COMMENT by @ZaniaStamataki & @kellyda60 summarise what we know so far about sudden onset #hepatitis of unexplained origin in childrenhttps://t.co/AYTR8wrG3C
Read-only link https://t.co/dgyzRhpODT#paediatrics pic.twitter.com/1WLQfaRrdx
— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) July 1, 2022
Monkeypox soars in Europe, with more than 4,000 cases.
4 Jul, 2022 | 12:43h | UTCMonkeypox soars in Europe, with more than 4,000 cases – CIDRAP
Original Report: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Monkeypox, Joint Epidemiological overview, 30 June, 2022
WHO Statement: No room for complacency – World Health Organization
Related:
Multi-country monkeypox outbreak: situation update – World Health Organization
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
RCT | CT vs. [18F]FDG-PET-CT for persistent or recurrent neutropenic fever in high-risk patients.
4 Jul, 2022 | 12:21h | UTC[18F]FDG-PET-CT compared with CT for persistent or recurrent neutropenic fever in high-risk patients (PIPPIN): a multicentre, open-label, phase 3, randomised, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)
Commentary on Twitter
NEW research: [18F]FDG-PET-CT resulted in more frequent antimicrobial rationalisation than CT in patients w/ haem diseases & persistent/recurrent high-risk neutropenic fever after chemotherapy. Results of the ph3 RCT PIPPIN #radonc #hemonc https://t.co/isOPFZVVpY pic.twitter.com/PVd8yFy7Ck
— The Lancet Haematology (@TheLancetHaem) June 29, 2022
M-A | Antibiotics for preventing recurrent urinary tract infection.
4 Jul, 2022 | 12:17h | UTCBrief Review | Ventilator-associated pneumonia.
4 Jul, 2022 | 12:15h | UTCVentilator-associated pneumonia – Intensive Care Medicine (if the link is paywalled, try this one in PMC)
Commentary on Twitter
VAP, main challenges & lessons learned
➡️ epidemiology: surveillance & data from LMICs
➡️ pathophysiology
➡️ prevention bundle
➡️ gold standard for diagnosis & microbiology
➡️ treatment: appropriate/timely ABTs
➡️ MDR pathogens
➡️ #COVID19: VAP's back
📎 https://t.co/oYblI6OGLK pic.twitter.com/qXWcABsU0H— Intensive Care Medicine (@yourICM) July 1, 2022
2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.
1 Jul, 2022 | 11:50h | UTCRelated:
Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.
1 Jul, 2022 | 11:49h | UTCCommentaries:
Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)
Commentary on Twitter (thread – click for more)
Early in the pandemic we wondered whether antithrombotic therapy in outpatients with #COVID19 would prevent #thrombosis ❓
Several trials were started globally and the ACTIV-4B trial was previously reported⬇️ https://t.co/Q15WcZwDIA
Now, we publish the OVID and ETHIC trials🧵
— The Lancet Haematology (@TheLancetHaem) June 30, 2022
Accuracy of rapid antigen vs. RT-PCR testing for SARS-CoV-2 infection in college athletes during prevalence of the Omicron variant.
1 Jul, 2022 | 11:39h | UTC
Commentary on Twitter
In this case series of college athletes returning to campus during Omicron, rapid antigen tests were 63% sensitive, >99% specific for #COVID19, similar to previous strains and less well in detecting asymptomatic #SARSCoV2. @helixcardinal @stanford_ortho https://t.co/SBPr6NQ9Na
— JAMA Network Open (@JAMANetworkOpen) June 15, 2022
Cohort Study: Effectiveness of Pfizer, Moderna, and AstraZeneca vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting.
1 Jul, 2022 | 11:37h | UTC
Commentary on Twitter
🎉 Read our latest research article comparing the effectiveness of three #COVID vaccines against severe COVID outcomes. ▶️ https://t.co/uaQNgnDrrV#BMJMedicine #MedTwitter #openaccess pic.twitter.com/4oeG5d0j80
— BMJMedicine (@BMJMedicine) June 16, 2022
Review: Lassa Virus Infection.
1 Jul, 2022 | 10:38h | UTCLassa Virus Infection: a Summary for Clinicians – International Journal of Infectious Diseases
Cohort Study: Pfizer vaccine effectiveness against omicron in children 5 to 11 years of age.
30 Jun, 2022 | 11:21h | UTC
Wearable activity trackers plus AI might be used to pick up presymptomatic COVID-19.
30 Jun, 2022 | 11:18h | UTCNews Release: Wearable activity trackers + AI might be used to pick up presymptomatic COVID-19 – BMJ Newsroom
Systematic Review: Long distance airborne transmission of SARS-CoV-2.
30 Jun, 2022 | 11:17h | UTCLong distance airborne transmission of SARS-CoV-2: rapid systematic review – The BMJ
Editorial: Airborne SARS-CoV-2 – The BMJ
News Release: New review of evidence highlights importance of adequate ventilation to prevent spread of covid-19 in indoor settings – BMJ
Brief Review: Update on prevention of intra-vascular accesses complications.
30 Jun, 2022 | 10:38h | UTCUpdate on prevention of intra-vascular accesses complications – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Update on intra-vascular accesses complications
🎯 choice
🗝 key measures to prevent CRBSI
Most of times CVL essential in #ICU but deescalation to PVL to be promoted. ⬆️ occlusions/thrombosis w midline/PICCS, CRBSI similar to CVL; interesting out ICU.
🖇 https://t.co/XVxJDkOL4i pic.twitter.com/iIQNEXctoe— Intensive Care Medicine (@yourICM) June 30, 2022
RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.
29 Jun, 2022 | 12:10h | UTCNews Releases:
Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London
Commentaries:
Commentary on Twitter
NEW Research—2-week interruption of methotrexate treatment for people w/ immune-mediated inflammatory diseases = enhanced boosting of antibody responses after #COVID19 vaccination
From Prof Abhishek Abhishek & colleagues https://t.co/y14pUEaB5X pic.twitter.com/pLvaXjJzoz
— The Lancet Respiratory Medicine (@LancetRespirMed) June 28, 2022
Perspective | Fast-evolving COVID variants complicate vaccine updates.
29 Jun, 2022 | 12:01h | UTCFast-evolving COVID variants complicate vaccine updates – Nature
Retrospective Cohort Study: Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation.
29 Jun, 2022 | 11:54h | UTC
An analysis of SARS-CoV-2 vaccine reactogenicity: variation by type, dose, and history, severity, and recency of prior SARS-CoV-2 infection.
29 Jun, 2022 | 11:52h | UTC