Infectious Diseases (all articles) | Page 31 of 298 | Links Medicus Content Curation & Alerts in Medicine

1⃣8⃣ million children did not receive a single vaccine in 2021 – the largest ↘️ in 29 years, due to:

🔸 #COVID19-related disruptions
🔸 emergencies
🔸 misinformation undermining vaccine acceptance & demand

WHO & @UNICEF sound the alarm 🚨

🆕 data on global vaccine coverage ⬇️

— World Health Organization (WHO) (@WHO) July 14, 2022

Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.

18 Jul, 2022 | 11:34h | UTC

Reactogenicity of Simultaneous COVID-19 mRNA Booster and Influenza Vaccination in the US – JAMA Network Open

Commentaries:

More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP

Reactogenicity and Concomitant Administration of the COVID-19 Booster and Influenza Vaccine – JAMA Network Open

Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.

18 Jul, 2022 | 11:30h | UTC

Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review – The BMJ

News Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom

RCT | Efficacy and safety of topical nitric oxide releasing Berdazimer gel in patients with molluscum contagiosum.

18 Jul, 2022 | 11:12h | UTC

Efficacy and Safety of Topical Nitric Oxide−Releasing Berdazimer Gel in Patients With Molluscum Contagiosum: A Phase 3 Randomized Clinical Trial – JAMA Dermatology

Commentary on Twitter

This randomized, vehicle-controlled trial of molluscum contagiosum patients found the efficacy and safety of a once-daily application of berdazimer gel, 10.3% an experimental topical, nitric oxide-releasing medication. https://t.co/zKuA29BTPS

— JAMA Dermatology (@JAMADerm) July 13, 2022

M-A of RCTs | Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy.

18 Jul, 2022 | 11:03h | UTC

Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy: a meta-analysis of randomized clinical trials – Clinics

M-A | Global trends in the proportion of Macrolide-resistant Mycoplasma pneumoniae infections.

18 Jul, 2022 | 10:50h | UTC

Global Trends in the Proportion of Macrolide-Resistant Mycoplasma pneumoniae Infections: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

This meta-analysis found the proportion of Mycoplasma pneumoniae (MRMP) showed an increasing trend with regional difference. The proportion of MRMP was highest in the Western Pacific Regions. Strategies to prevent the spread of MRMP are urgently needed. https://t.co/78qmC9l9z1

— JAMA Network Open (@JAMANetworkOpen) July 11, 2022

RCT | Tixagevimab-cilgavimab for treatment of patients hospitalized with COVID-19.

15 Jul, 2022 | 13:02h | UTC

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial – The Lancet Respiratory Medicine

Commentary: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 – New England Journal of Medicine

Commentary on Twitter

In pts hospitalised w/ COVID-19 receiving remdesivir and other standard care, tixagevimab–cilgavimab did not improve time to sustained recovery but was safe and mortality was lower vs placebo

From the ACTIV-3–TICO Study Group https://t.co/zaaXBQYl5t pic.twitter.com/xe0tmbFrZ9

— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022

Review | Invasive respiratory fungal infections in COVID-19 critically ill patients.

15 Jul, 2022 | 12:58h | UTC

Invasive Respiratory Fungal Infections in COVID-19 Critically Ill Patients – Journal of Fungi

7 of your most pressing monkeypox vaccine questions, answered – “We have safe, effective options — but in short supply”.

15 Jul, 2022 | 13:00h | UTC

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

Review | Strongyloides stercoralis.

15 Jul, 2022 | 12:23h | UTC

Strongyloides stercoralis – Lung (if the link is paywalled, try this one)

FDA authorizes emergency use of Novavax COVID-19 vaccine.

14 Jul, 2022 | 13:01h | UTC

Coronavirus (COVID-19) Update: FDA Authorizes Emergency Use of Novavax COVID-19 Vaccine, Adjuvanted – U.S. Food & Drug Administration

Commentaries:

FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT

US regulators OK new COVID-19 shot option from Novavax – Associated Press

WHO Updated Report | Severe acute hepatitis of unknown etiology in children.

14 Jul, 2022 | 12:54h | UTC

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

A case series of children with acute hepatitis and human Adenovirus infection.

14 Jul, 2022 | 12:56h | UTC

A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)

Commentaries on Twitter

A majority of children admitted to a single hospital in late 2021–early 2022 with acute hepatitis of unknown cause tested positive for adenovirus. This report describes the children’s illnesses and outcomes. https://t.co/QYvi6U1jUN pic.twitter.com/auPRq1duQm

— NEJM (@NEJM) July 13, 2022

From January–April 2022, 44 children with acute hepatitis of unknown cause were referred to a liver-transplantation center in the U.K. Six underwent liver transplantation. https://t.co/CMI4KCqdxM pic.twitter.com/og72u58L5R

— NEJM (@NEJM) July 13, 2022