Infectious Diseases (all articles)
RCT | 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy.
4 Aug, 2022 | 14:33h | UTCRelated:
WHO Recommends Dolutegravir as Preferred HIV Treatment Option in All Populations
RCT: Dolutegravir or Darunavir in combination with Zidovudine or Tenofovir to treat HIV.
M-A | Efficacy of Doxycycline for mild-to-moderate community-acquired pneumonia in adults.
4 Aug, 2022 | 14:17h | UTCEfficacy of Doxycycline for Mild-to-moderate Community-acquired Pneumonia in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
?⚡⚡Systematic Review and Meta-analysis of Randomized Controlled Trials @CIDJournal
Efficacy of Doxycycline for Mild-to-moderate CAP in Adults
The efficacy of doxycycline was comparable to macrolides or fluoroquinolones in mild-moderate CAP #IDTwitter https://t.co/L7UBBUc4Dm— Antibiotic Steward Bassam Ghanem?⚡ (@ABsteward) July 29, 2022
M-A | The global burden of sore throat and group A Streptococcus pharyngitis.
4 Aug, 2022 | 13:33h | UTC
Network M-A | Evidence synthesis evaluating body weight gain among people treating HIV with antiretroviral therapy.
4 Aug, 2022 | 13:30h | UTC
Commentary on Twitter
A new systematic review aimed to evaluate how different #ART regimens compare with respect to body #weight gains over time and associated risk factors.
Read here: https://t.co/MHC1Ysgb34 pic.twitter.com/0djjGPmlcW
— eClinicalMedicine – The Lancet Discovery Science (@eClinicalMed) May 24, 2022
RECOVERY Trial | Baricitinib in patients admitted to hospital with COVID-19.
3 Aug, 2022 | 14:34h | UTCInvited Commentary: Baricitinib in COVID-19: a coming-of-age from artificial intelligence to reducing mortality – The Lancet
Related:
WHO recommends two new drugs to treat COVID-19 – World Health Organization
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary on Twitter
New @TheLancet
The largest trial of baricitinib, a JAK-inhibitor drug repurposed via #AI data mining, reduced Covid mortality and the overall reduction consistent with 8 previous RCTs (~20%)https://t.co/5fHDBBvm3Q pic.twitter.com/GDFzcU26H6— Eric Topol (@EricTopol) July 29, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
Antivirals with activity against Monkeypox: a clinically oriented review.
3 Aug, 2022 | 14:26h | UTCRelated:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Review | Diagnosis, treatment, and prevention of Malaria in the US.
3 Aug, 2022 | 14:27h | UTCDiagnosis, Treatment, and Prevention of Malaria in the US: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis, Treatment, and Prevention of Malaria in the US – JAMA
Cohort Study | Association of higher-dose fluoroquinolone therapy with serious adverse events in older adults with advanced chronic kidney disease.
3 Aug, 2022 | 14:22h | UTC
M-A | Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021.
3 Aug, 2022 | 14:04h | UTC
Cohort Study | Incidence of acute chest syndrome in children with sickle cell disease following implementation of the 13-valent pneumococcal conjugate vaccine.
3 Aug, 2022 | 13:53h | UTC
Commentary on Twitter
#OrigInvestigation: Reduction of acute chest syndrome incidence in children with sickle-cell disease following 13-valent pneumococcal conjugate vaccine (PCV13) implementation in France. https://t.co/MuG6T0g5FU
— JAMA Network Open (@JAMANetworkOpen) August 2, 2022
WHO Guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations.
2 Aug, 2022 | 12:41h | UTCNews Release: WHO publishes new guidelines on HIV, hepatitis and STIs for key populations – World Health Organization
Severe acute hepatitis of unknown etiology in children—what is known?
2 Aug, 2022 | 12:39h | UTCSevere acute hepatitis of unknown aetiology in children—what is known? – BMC Medicine
Related:
A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
M-A | Perioperative care bundles for the prevention of surgical-site infections.
2 Aug, 2022 | 12:30h | UTC
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox.
1 Aug, 2022 | 12:24h | UTCWHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
See also: WHO recommends gay and bisexual men limit sexual partners to reduce the spread of monkeypox – CNBC
Related:
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
The #monkeypox outbreak can be stopped if countries, communities and individuals inform themselves, take the risks seriously, and take the steps needed to stop transmission and protect vulnerable groups.pic.twitter.com/7CumPFyPhc
— Tedros Adhanom Ghebreyesus (@DrTedros) July 27, 2022
Monkeypox | A contemporary review for healthcare professionals.
1 Aug, 2022 | 12:20h | UTCMonkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Related:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Clinical features and novel presentations of human monkeypox in a central London center during the 2022 outbreak: descriptive case series.
1 Aug, 2022 | 12:22h | UTCRelated:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
NEW research published by The BMJ today identifies important differences in monkeypox symptoms between the current outbreak and previous outbreaks in endemic regions https://t.co/uYnhbZoBhd pic.twitter.com/NZNoNVi6Lm
— The BMJ (@bmj_latest) July 29, 2022
Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.
29 Jul, 2022 | 12:39h | UTCRapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library
Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library
M-A | Lung cancer occurrence after an episode of tuberculosis.
29 Jul, 2022 | 12:28h | UTC
M-A | Prognosis and persistence of smell and taste dysfunction in patients with covid-19.
28 Jul, 2022 | 13:28h | UTCEditorial: Smell and taste dysfunction after covid-19 – The BMJ
Commentary: The burden of prolonged smell and taste loss in covid-19 – The BMJ
News Release: Millions of covid patients may have long term smell and taste problems – BMJ Newsroom
RCT | Short vs. extended treatment with a carbapenem in patients with high-risk fever of unknown origin during neutropenia.
27 Jul, 2022 | 12:17h | UTCShort versus extended treatment with a carbapenem in patients with high-risk fever of unknown origin during neutropenia: a non-inferiority, open-label, multicentre, randomised trial – The Lancet Haematology (link to abstract – $ for full-text)
Commentary: Short-Course or Extended Antibiotics in Febrile Neutropenia? – Medscape (free registration required)
Commentary on Twitter
NEW online—Short-term is not inferior to extended carbapenem in patients with haematological malignancy and neutropenic fever of unknown origin, however, higher serious adverse events and mortality were noted in the short treatment group: the SHORT trial https://t.co/FOp1M3D6cL pic.twitter.com/6z5e8MSEgQ
— The Lancet Haematology (@TheLancetHaem) June 10, 2022
M-A | Antiviral drug treatment for nonsevere COVID-19.
27 Jul, 2022 | 12:14h | UTCNews Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal
Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP
M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.
27 Jul, 2022 | 12:12h | UTC
NICE Guideline | Pneumonia in adults: diagnosis and management.
26 Jul, 2022 | 13:37h | UTCPneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence
Related Guidelines:
Pneumonia (community-acquired): antimicrobial prescribing
Pneumonia (hospital-acquired): antimicrobial prescribing
Cohort Study | Cardiometabolic outcomes up to 12 months after COVID-19 infection.
26 Jul, 2022 | 13:30h | UTCNews Release: COVID-19 patients more likely to develop cardiovascular diseases and diabetes soon after infection – PLOS
Commentaries:
COVID-19 tied to new-onset, short-term heart disease, diabetes – CIDRAP
CVD, Diabetes Spike in Acute Phase of COVID-19 – TCTMD
Monkeypox virus infection in humans across 16 countries — April–June 2022.
25 Jul, 2022 | 13:09h | UTCCommentary: Largest monkeypox study to date highlights new symptoms – CIDRAP
Related: WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Commentary on Twitter
In this report, 528 cases of monkeypox across 16 countries are described. Rash, mucosallesions, fever, lethargy, and lymphadenopathy were common clinical findings. Few patients were hospitalized. https://t.co/SPTVK1vBRl pic.twitter.com/PNWDuAb7AG
— NEJM (@NEJM) July 21, 2022