Infectious Diseases (all articles) | Page 262 of 298 | Links Medicus Content Curation & Alerts in Medicine

Randomized Trial: New Single-Dose Oral Drug for Treatment of Gonorrhea

9 Nov, 2018 | 02:56h | UTC

Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Novel antibiotic shows promise in treatment of uncomplicated gonorrhea – NIH News Release (free) AND Experimental treatment appears effective against gonorrhea in small study – STAT (free) AND Single Dose of New Oral Antibiotic Cures Most Gonorrhea – Medscape (free registration required)

Randomized Trial: Triple-Drug Treatment for Lymphatic Filariasis

9 Nov, 2018 | 02:58h | UTC

A Trial of a Triple-Drug Treatment for Lymphatic Filariasis – New England Journal of Medicine (free)

Editorial: Advancing toward the Elimination of Lymphatic Filariasis (free)

Commentary: Triple-Drug Therapy Superior to Two Drugs for Treating Lymphatic Filariasis – NEJM Journal Watch (free)

Meta-Analysis: Diagnostic Value of Symptoms and Signs for Identifying UTI in Older adults

9 Nov, 2018 | 02:05h | UTC

Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: Systematic review and meta-analysis – The Journal of Infection (free)

“A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients.”

CDC Recommendations for Use of Hepatitis A Vaccine for Postexposure Prophylaxis and for Preexposure Prophylaxis for International Travel

8 Nov, 2018 | 12:01h | UTC

Update: Recommendations of the Advisory Committee on Immunization Practices for Use of Hepatitis A Vaccine for Postexposure Prophylaxis and for Preexposure Prophylaxis for International Travel – Centers for Disease Control and Prevention (free)

Commentary: CDC Updates Guidelines on Pre- and Postexposure Protection Against Hepatitis A – NEJM Journal Watch (free)

Study: Shorter Treatment May Be Effective for Selected Patients with Tuberculosis

6 Nov, 2018 | 15:52h | UTC

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis – Nature Medicine (link to abstract – $ for full-text)

Commentary: Pulmonary TB can be cured with shorter treatment, study finds – University of California – San Francisco (free)

Study: Antibiotic Prophylaxis and Incidence of Endocarditis

6 Nov, 2018 | 15:45h | UTC

Antibiotic Prophylaxis and Incidence of Endocarditis Before and After the 2007 AHA Recommendations – Journal of the American College of Cardiology (free)

Commentary: International study supports the use of antibiotic prophylaxis to prevent a life-threatening heart infection in high risk dental patients – contrary to NICE guidance that recommended against its use in the UK – The University of Sheffield (free)

Study: Association of Prior Vaccination With Influenza Vaccine Effectiveness in Children

6 Nov, 2018 | 15:41h | UTC

Association of Prior Vaccination With Influenza Vaccine Effectiveness in Children Receiving Live Attenuated or Inactivated Vaccine – JAMA Network Open (free)

Commentaries: Repeated Vaccination May Protect Children From Influenza Infection – JAMA Network Open (free) AND What Getting The Flu Vaccine Every Year Does To Your Immunity – Forbes (free) AND Study: Kids’ flu vaccine protection not reduced by prior vaccination – CIDRAP (free)

Report: English Surveillance Programme for Antimicrobial Utilisation and Resistance

6 Nov, 2018 | 15:38h | UTC

English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR): Report 2018 – Public Health England (free PDF)

Commentaries: How antibiotic resistance could take us back to the ‘dark ages’ – BBC (free) AND Over three million surgical operations and cancer treatments a year in England may become life-threatening without antibiotics – NHS (free) AND UK parliament urges making antimicrobial resistance a priority – CIDRAP (free)

Case Report: Fatal Measles Case Highlights Importance of Herd Immunity in Protecting the Vulnerable

5 Nov, 2018 | 12:09h | UTC

Case Report: Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient – Open Forum Infectious Diseases (free)

Commentary: Fatal measles case highlights importance of herd immunity in protecting the vulnerable – Infectious Diseases Society of America (free)

NICE Antimicrobial Prescribing Guidelines

2 Nov, 2018 | 03:51h | UTC

Antimicrobial prescribing guidelines – National Institute for Health and Care Excellence (free resources)

Just Published Guidelines: Urinary tract infection (lower): antimicrobial prescribing (free) AND Urinary tract infection (recurrent): antimicrobial prescribing (free) AND Pyelonephritis (acute): antimicrobial prescribing (free) AND Prostatitis (acute): antimicrobial prescribing (free)

A Brief History of Evolving Diagnostics and Therapy for Gonorrhea

5 Nov, 2018 | 11:42h | UTC

A Brief History of Evolving Diagnostics and Therapy for Gonorrhea: Lessons Learned – Clinical Infectious Diseases (free)

Systematic Review: Prophylactic Antibiotic Therapy for COPD

2 Nov, 2018 | 03:36h | UTC

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)

Summary: Preventative antibiotic therapy for people with COPD – Cochrane Library (free)

“Use of continuous and intermittent prophylactic antibiotics results in a clinically significant benefit in reducing exacerbations in COPD patients.”

Study: Antibiotic and Acid-Suppression Medications During Early Childhood are Associated with Obesity

2 Nov, 2018 | 03:32h | UTC

Antibiotic and acid-suppression medications during early childhood are associated with obesity – Gut (free)

Commentaries: Expert reaction to antibiotic and antacid use in early childhood and risk of obesity – Science Media Centre (free) AND Antibiotic Exposure in Early Life Tied to Slightly Higher Obesity Risk – NEJM Journal Watch (free) AND Antibiotics, H2RAs and PPIs linked to child obesity – OnMedica (free) AND Two studies tie early antibiotic exposure to increased obesity risk – CIDRAP (free)

Perspective: Overdiagnosis of Penicillin Allergy Leads to Costly, Inappropriate Treatment

2 Nov, 2018 | 02:23h | UTC

Overdiagnosis of Penicillin Allergy Leads to Costly, Inappropriate Treatment – JAMA (free for a limited period)

Related: NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk (free) AND Antibiotic Use After Removal of Penicillin Allergy Label (link to abstract and commentaries) AND Allergy Testing in Children With Low-Risk Penicillin Allergy Symptoms (link to abstract and commentaries)

Meta-Analysis: Efficacy, Effectiveness, and Safety of Herpes Zoster Vaccines

26 Oct, 2018 | 02:42h | UTC

Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis – The BMJ (free)

“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”

Meta-Analysis: Cefazolin vs. Antistaphylococcal Penicillins for MSSA Bacteremia

26 Oct, 2018 | 02:27h | UTC

Efficacy and safety of cefazolin versus antistaphylococcal penicillins for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia: a systematic review and meta-analysis – BMC Infectious Diseases (free)

Randomized Trial: Decontamination Strategies and Bloodstream Infections with Antibiotic-Resistant Microorganisms in Ventilated Patients

26 Oct, 2018 | 01:57h | UTC

Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Decontamination of Oral or Digestive Tract for Patients in the Intensive Care Unit (free for a limited period)

“Among patients receiving mechanical ventilation in ICUs with moderate to high ABX resistance prevalence, use of chlorhexidine mouthwash, selective oropharyngeal decontamination, or selective digestive tract decontamination was not associated with reductions in ICU-acquired bloodstream infections caused by MDRGNB vs standard care” (via @JAMA_current see Tweet with visual abstract)