Infectious Diseases (all articles)
Antimicrobial Stewardship in Cancer Patients: The Time is Now
21 Jul, 2019 | 21:53h | UTC
Study: Persistent HIV-infected Cells in Cerebrospinal Fluid Associated with Cognitive Impairment
19 Jul, 2019 | 09:41h | UTCCommentaries: Persistent HIV in central nervous system linked to cognitive impairment – NIH News Release (free) AND HIV-infected cells persist in cerebrospinal fluid, linked to poorer neurocognitive performance – University of North Carolina School of Medicine (free)
WHO Declares New Ebola Outbreak a Public Health Emergency of International Concern
18 Jul, 2019 | 11:12h | UTCNews Release: Ebola outbreak in the Democratic Republic of the Congo declared a Public Health Emergency of International Concern – World Health Organization (free)
Commentaries: DR Congo Ebola outbreak now a Public Health Emergency, UN health agency declares – United Nations (free) AND WHO declares public health emergency over DRC Ebola – CIDRAP (free) AND WHO sounds Ebola alarm as risks intensify – Reuters (free) AND The WHO finally declared a public health emergency over Ebola – Vox (free)
See also: Statement by the Emergency Committee (free PDF)
Related: Special Report: The Ongoing Ebola Epidemic in the Democratic Republic of Congo, 2018–2019 – New England Journal of Medicine (free) AND Comprehensive Review: Ebola virus disease – The Lancet (free)
Related Commentary on Twitter
BREAKING NEWS: The #Ebola outbreak in #DRC constitutes a public health emergency of international concern, citing concerning geographical expansion of the virus: WHO Director-General, @DrTedros following the IHR Emergency Committee’s recommendation #alert
— World Health Organization (WHO) (@WHO) July 17, 2019
Three Large Studies Tested the Effects of Universal HIV Testing and Treatment
18 Jul, 2019 | 10:38h | UTCOriginal Studies: Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana – New England Journal of Medicine (free) AND Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART) – New England Journal of Medicine (free) AND HIV Testing and Treatment with the Use of a Community Health Approach in Rural Africa – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Intensive Anti-H.I.V. Efforts Meet With Mixed Success in Africa – The New York Times (10 articles per month are free) AND HIV Incidence: Effect of Universal Testing and Treatment – MedicalResearch.com (free) AND New HIV program increased viral suppression, decreased new infections in Botswana – Harvard T.H. Chan School of Public Health (free)
Cohort Study: State-Mandated Protocolized Sepsis Care Linked to Lower Mortality
17 Jul, 2019 | 10:36h | UTCAssociation Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis – JAMA (free for a limited period)
Editorial: Government Regulation of Sepsis Care (free for a limited period)
Commentaries: First Ever State Sepsis Regulation in U.S. Tied to Lower Death Rates – University of Pittsburg (free) AND Regulations That Mandate Sepsis Care Appear To Have Worked In New York – NPR (free)
Regimens to Treat Multidrug-resistant Tuberculosis: Past, Present and Future Perspectives
16 Jul, 2019 | 09:20h | UTCRelated: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free)
Clinical Practice: Measles
14 Jul, 2019 | 20:05h | UTCMeasles – New England Journal of Medicine (free)
Urinary Tract Infections Affect Millions. The Cures Are Faltering.
14 Jul, 2019 | 19:49h | UTCUrinary Tract Infections Affect Millions. The Cures Are Faltering. – The New York Times (10 articles per month are free)
“As the infections become increasingly resistant to antibiotics, some standard treatments no longer work for an ailment that was once easily cured.”
A Current Appraisal of Evidence for the Approach to Sepsis and Septic Shock
14 Jul, 2019 | 19:43h | UTCSource: Critical Care Reviews Newsletter
Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers
12 Jul, 2019 | 07:44h | UTCCommentaries: No link between flu vaccine in pregnancy and later health problems in children – The BMJ (free) AND Swine flu jab in pregnancy safe for children as well as mothers – OnMedica (free)
[Abstract Only] Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations
11 Jul, 2019 | 11:18h | UTCC-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: CRP Testing Can Safely Reduce Antibiotic Use for COPD Exacerbations – NEJM Journal Watch (free) AND Fingerprick Biomarker Test Can Reduce Use of Antibiotics in COPD Flares – MedicalResearch.com (free)
HPV Vaccine Could Prevent over 100,000 Cancers in the UK
11 Jul, 2019 | 09:41h | UTCPress Release: HPV vaccine could prevent over 100,000 cancers – Public Health England (free)
Commentaries: HPV vaccine for boys ‘will prevent thousands of cancers’ – BBC (free) AND Expert reaction to HPV vaccine, modelling of cancer prevention, and introduction in September of vaccine programme for boys – Science Media Centre (free) AND UK offers HPV vaccines to boys, aims to stop 100,000 cancer cases – Reuters (free)
[Abstract Only] Study: Nearly A Third of Children Exposed to Zika In-utero Develop Neurological Problems by Age 3
10 Jul, 2019 | 09:53h | UTCDelayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)
News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)
Related Commentary on Twitter
Nearly one third of infants born to mothers with confirmed #Zika virus (ZIKV) infection during pregnancy have developmental impairments with delayed presentations that warrant long term monitoring of ZIKV-exposed children | https://t.co/1i1Yo9Tz5E @fiocruz_en @dgsomucla pic.twitter.com/XEQVLX3PwK
— Nature Medicine (@NatureMedicine) July 8, 2019
AAP Clinical Report: Management of Infants at Risk for Group B Streptococcal Disease
10 Jul, 2019 | 10:06h | UTCManagement of Infants at Risk for Group B Streptococcal Disease – Pediatrics (free)
News Releases: AAP Updates Guidance on Preventing, Managing Infants with Group B Strep Disease – American Academy of Pediatrics (free) AND Early-onset group B strep: New guidance includes changes in dosing, assessment – AAP News (free)
Related: ACOG Guideline: Prevention of Early-Onset Group B Streptococcal Disease in Newborns (free)
[Abstract Only] Cohort Study: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized with Pneumonia
9 Jul, 2019 | 10:13h | UTCExcess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Pneumonia patients get too many antibiotics – especially as they leave the hospital – University of Michigan (free)
Related Commentary on Twitter
https://twitter.com/ABsteward/status/1148384237499899904
Meta-Analysis: Quadruple vs. Triple Combination Antiretroviral Therapies for Treatment-Naive People with HIV
9 Jul, 2019 | 09:41h | UTC
Global Epidemiology of Emerging Candida Auris
8 Jul, 2019 | 10:15h | UTCGlobal epidemiology of emerging Candida auris – Current Opinion in Microbiology (free)
Related: The global challenge of Candida auris in the intensive care unit – Critical Care (free) AND Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris – Journal of Intensive Care (free) AND Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally – PLOS Pathogens (free)
Guideline for the Antibiotic Use in Acute Gastroenteritis
8 Jul, 2019 | 10:18h | UTCGuideline for the Antibiotic Use in Acute Gastroenteritis – Infection & Chemotherapy (free)
Related: ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults – American Journal of Gastroenterology (free)
Global Burden of Latent Multidrug-resistant Tuberculosis
8 Jul, 2019 | 10:08h | UTCCommentaries: The burden of latent multidrug-resistant tuberculosis – The Lancet Infectious Diseases (free)
Related Commentary on Twitter
New online> Global burden of latent multidrug-resistant #tuberculosis: trends and estimates based on mathematical modelling #TB https://t.co/IbyhjxRLXe
— The Lancet Infectious Diseases (@TheLancetInfDis) July 5, 2019
The Zika Virus Is Still a Threat. Here’s What the Experts Know.
4 Jul, 2019 | 11:11h | UTCThe Zika Virus Is Still a Threat. Here’s What the Experts Know. – The New York Times (10 articles per month are free)
Related WHO Report: Zika epidemiology update – July 2019 (free PDF)
Review: Infections in the Elderly Critically-Ill Patients
3 Jul, 2019 | 06:05h | UTCInfections in the Elderly Critically-Ill Patients – Frontiers in Medicine (free)
Pathophysiology, Diagnosis, and Management of Infections in Atopic Dermatitis
2 Jul, 2019 | 01:04h | UTC
2019 European Guideline on the Management of Lymphogranuloma Venereum
30 Jun, 2019 | 18:07h | UTC
Clinical Update: Syphilis
30 Jun, 2019 | 17:53h | UTCSyphilis – The BMJ (free)
Related: WHO Guidelines for the Treatment of Treponema pallidum (Syphilis) – World Health Organization (free)
Study: Most Cases of Severe Pneumonia in Children Caused by Virus
30 Jun, 2019 | 17:51h | UTCCommentaries: What the PERCH study means for future pneumonia strategies – The Lancet (free) AND Study: Viruses cause most global pediatric pneumonia – CIDRAP (free)
Related Commentary on Twitter
Causes of severe #pneumonia in children: The viruses accounted for 61•4% , whereas bacteria accounted for 27•3% and M. Tb for 5•9%. Viruses were less common (54•5%, vs 68•0%) & bacteria more common (33•7% vs 22•8%) in very severe pneumonia cases. https://t.co/7CT5Yqqs0w pic.twitter.com/5ZK8w7Cbci
— Vipin M. Vashishtha (@vipintukur) June 29, 2019