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Infectious Diseases (all articles)

Clinical Update – Preventing Surgical Site Infections: Looking Beyond the Current Guidelines

23 Feb, 2020 | 22:21h | UTC

Preventing Surgical Site Infections: Looking Beyond the Current Guidelines – JAMA (free for a limited period)

Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control (free) AND Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines – World Journal of Emergency Surgery (free)

 

Community-acquired Pneumonia in Critically Ill Very Old Patients: A Growing Problem

23 Feb, 2020 | 22:06h | UTC

Community-acquired pneumonia in critically ill very old patients: a growing problem – European Respiratory Review (free)

Editorial: Natural enemy or friend? Pneumonia in the very elderly critically ill patient (free)

 

Global Burden of Respiratory Infections Associated with Seasonal Influenza in Children Under 5 Years

21 Feb, 2020 | 08:34h | UTC

Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study – The Lancet Global Health (free)

Invited Commentary: The burden of viral respiratory infections in young children in low-resource settings (free)

 

[Abstract Only] Study: Yield, Efficiency and Costs of Mass Screening Algorithms for Tuberculosis in Brazilian Prisons

21 Feb, 2020 | 07:31h | UTC

Yield, Efficiency and Costs of Mass Screening Algorithms for Tuberculosis in Brazilian Prisons – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentary: Mass TB screening with point-of-care test is cost-effective, Brazil prison study shows – Science Speaks: Global ID News (free)

 

[Abstract Only] Cluster-Randomized Trial: Contact Isolation vs. Standard Precautions to Decrease Acquisition of Extended-spectrum β-lactamase-producing Enterobacterales in Non-critical Care Wards

21 Feb, 2020 | 07:26h | UTC

Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 

Study: A Deep Learning Approach to Antibiotic Discovery

21 Feb, 2020 | 07:23h | UTC

A Deep Learning Approach to Antibiotic Discovery – Cell (free for a limited period)

Commentaries: Powerful antibiotics discovered using AI – Nature (free) AND Aided by machine learning, scientists find a novel antibiotic able to kill superbugs in mice – STAT (free)

 

Cohort Study: Macrolide Antibiotics in Early Pregnancy Linked to Increased Risk of Birth Defects

20 Feb, 2020 | 10:51h | UTC

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study – The BMJ (free)

Commentaries: Warning over prescribing antibiotics during pregnancy – OnMedica (free) AND Some antibiotics prescribed during pregnancy linked with birth defects – BMJ (free) AND Expert reaction to study looking at macrolide antibiotics in pregnancy and birth defects – Science Media Centre (free) AND Macrolide Antibiotics Early in Pregnancy Tied to Birth Defects – The New York Times (10 articles per month are free)

 

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

20 Feb, 2020 | 10:40h | UTC

Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)

Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)

Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)

 

China Releases Largest Study on COVID-19 Outbreak with Over 44.000 Patients – Elderly and Sick are Most at Risk

19 Feb, 2020 | 10:23h | UTC

The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020 – China CDC Weekly (free PDF – link via Forbes)

Commentaries: Coronavirus: Largest study suggests elderly and sick are most at risk – BBC (free) AND New Chinese Study Finds That The Elderly Are Most At Risk From The Coronavirus [Infographic] – Forbes (free) AND Expert reaction to WHO Director General’s statement on new paper from China detailing over 44,000 of their cases – Science Media Centre (free)

 

Perspective – “Antimicrobial Stewardship Failure: Time for a New Model”

19 Feb, 2020 | 10:12h | UTC

Antimicrobial stewardship failure: time for a new model – Journal of Antimicrobial Chemotherapy (free)

 

Related Commentary on Twitter

 

Here are 10 of the Most Urgent Health Challenges We’ll Face in the 2020s, According to WHO

19 Feb, 2020 | 10:14h | UTC

Here are 10 of the most urgent health challenges we’ll face in the 2020s, according to WHO – World Economic Forum (free)

Original WHO Statement: WHO’s List of Urgent Global Health Challenges for the New Decade (free statement and commentary)

 

Observational Study: Empirical Anti-MRSA Antibiotic Therapy Does Not Improve Outcomes in Patients Hospitalized for Pneumonia

18 Feb, 2020 | 08:15h | UTC

Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)

Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)

 

Related Commentary on Twitter

 

[Abstract Only] Randomized Trial: Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease

16 Feb, 2020 | 21:39h | UTC

A Randomized Controlled Trial of Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease – Clinical Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 

Bloodstream Infections in Critically Ill Patients: An Expert Statement

16 Feb, 2020 | 21:03h | UTC

Bloodstream infections in critically ill patients: an expert statement – Intensive Care Medicine (free)

 

Diabetes and TB—A Complicating Combo

16 Feb, 2020 | 20:59h | UTC

Diabetes and TB—A Complicating Combo – Think Global Health (free)

Related: Collaborative framework for care and control of tuberculosis and diabetes – World Health Organization (free) AND The Co-Management of Tuberculosis and Diabetes: Challenges and Opportunities in the Developing World – PLOS Medicine (free)

 

Principles of Vaccine Licensure, Approval, and Recommendations for Use

16 Feb, 2020 | 20:41h | UTC

Principles of Vaccine Licensure, Approval, and Recommendations for Use – Mayo Clinic Proceedings (free)

 

Immunization Strategies to Span the Spectrum of Immunocompromised Adults

16 Feb, 2020 | 20:43h | UTC

Immunization Strategies to Span the Spectrum of Immunocompromised Adults – Mayo Clinic Proceedings (free)

 

CDC Guidelines for the Treatment of Latent Tuberculosis Infection

14 Feb, 2020 | 02:22h | UTC

Guidelines for the Treatment of Latent Tuberculosis Infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020 – Centers for Disease Control and Prevention (free)

Related: WHO Guideline: Latent TB Infection (free) AND Study: Rifampicin is Likely to be the Safest Latent Tuberculosis Infection Treatment Option (free)

Commentary: Guidelines Updated on Treating Latent TB – NEJM Journal Watch (free)

 

Position Paper: Intraoperative Surgical Site Infection Control and Prevention

13 Feb, 2020 | 08:07h | UTC

Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines – World Journal of Emergency Surgery (free)

Related: Guidelines for the Prevention of Surgical Site Infections (free guidelines on the subject)

 

Recommended Childhood and Adolescent Immunization Schedule: United States, 2020

13 Feb, 2020 | 08:09h | UTC

Recommended Childhood and Adolescent Immunization Schedule: United States, 2020 – Pediatrics (free)

Table 1. Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger, United States, 2020 – Centers for Disease Control and Prevention (free)

Table 2. Catch-up immunization schedule for persons aged 4 months–18 years who start late or who are more than 1 month behind, United States, 2020 – Centers for Disease Control and Prevention (free)

Table 3. Recommended Child and Adolescent Immunization Schedule by Medical Indication, United States, 2020 – Centers for Disease Control and Prevention (free)

 

Randomized Trial: Incisional Negative Pressure Wound Therapy Does Not Reduce Deep Surgical Site Infections After Surgery for Lower Limb Fractures Associated with Major Trauma

13 Feb, 2020 | 08:02h | UTC

Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma: The WHIST Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Incisional Negative Pressure Wound Therapy Following Surgical Repair of Lower Extremity Fractures (free)

Commentary: Expensive new wound treatment method no more effective than cheap standard dressings – University of Warwick (free)

 

NICE Guideline: Antimicrobial Prescribing for Leg Ulcer Infection

12 Feb, 2020 | 07:35h | UTC

Leg ulcer infection: antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)

 

Related Commentary on Twitter

 

Randomized Trial: Among Patients with MRSA Bacteremia, the Addition of an Antistaphylococcal β-lactam to Standard Therapy Does Not Improve Outcomes

12 Feb, 2020 | 07:29h | UTC

Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Combination Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: Not Ready for Prime Time (free for a limited period)

Commentaries: Trial pours cold water on combo treatment for MRSA bacteremia – CIDRAP (free) AND Trial shows using two drugs not better than one when treating MRSA blood infections – University of Melbourne (free)

 

Related Commentary on Twitter

 

Critical Care Management of Adults with Community-acquired Severe Respiratory Viral Infection

11 Feb, 2020 | 02:25h | UTC

Critical care management of adults with community-acquired severe respiratory viral infection – Intensive Care Medicine (free)

 

Systematic Review: Schistosomiasis-associated Pulmonary Arterial Hypertension

11 Feb, 2020 | 01:59h | UTC

Schistosomiasis-associated pulmonary arterial hypertension: a systematic review – European Respiratory Review (free)

 

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