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Infectious Diseases (all articles)

Debate Podcast: John Ioannidis vs. Sten Vermund – Be It Resolved; We Are Making High-stakes Decisions About the COVID-19 Pandemic Without Reliable Data

31 Mar, 2020 | 04:45h | UTC

Be it resolved, we are making high-stakes decisions about the COVID-19 pandemic without reliable data. – Munk Debates Podcast

Related Video: Perspectives on the Pandemic with Dr. John Ioannidis

Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)

 


COVID-19: Risks Related to the Use of Hydroxychloroquine

31 Mar, 2020 | 04:48h | UTC

 


Study: SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19

31 Mar, 2020 | 04:40h | UTC

SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19 – Annals of Internal Medicine

Commentary: COVID-19 found in sputum and feces samples after pharyngeal specimens no longer positive – American College of Physicians

 


[Preprint] COVID-19: Hydroxychloroquine Beneficial in Small Trial

31 Mar, 2020 | 04:51h | UTC

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial – medRxiv

 


The Mathematics of Predicting the Course of the Coronavirus

31 Mar, 2020 | 04:43h | UTC

The Mathematics of Predicting the Course of the Coronavirus – Wired

See also: Mathematics of life and death: How disease models shape national shutdowns and other pandemic policies – Science AND How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian AND Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection – medRxiv

 


Ethical Considerations in the Allocation of Critical Care Resources When Capacity is Overwhelmed

31 Mar, 2020 | 04:37h | UTC

Ethical considerations in the allocation of critical care resources when capacity is overwhelmed – Canadian Journal of Emergency Medicine

 


Review: Oral Step-Down Therapy for the Treatment of Infective Endocarditis

31 Mar, 2020 | 04:33h | UTC

Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review – JAMA Internal Medicine (free for a limited period)

Author Interview: Evaluation of the Shift From Intravenous Antibiotics to Oral Step-Down Therapy for Infective Endocarditis (free)

 


“Immunity Certificates” to Leave Lockdown Early?

31 Mar, 2020 | 04:39h | UTC

 


JAMA Guideline Synopsis: Management of Critically Ill Adults With COVID-19

30 Mar, 2020 | 02:17h | UTC

Management of Critically Ill Adults With COVID-19 – JAMA

Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19

Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine

Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm

Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence

 


Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

30 Mar, 2020 | 02:12h | UTC

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA

Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges

Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI

See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration

 


N95 Re-Use Instructions

30 Mar, 2020 | 02:06h | UTC

N95 Re-Use Instructions – SAGES

Related: Conserving Supply of Personal Protective Equipment—A Call for Ideas – JAMA AND N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine

 


COVID-19: Controversies on the Use of Face Masks

30 Mar, 2020 | 02:10h | UTC

Related Guidance: WHO Recommendations on when and how to use masks – World Health Organization AND Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention

 


Primary Care & Coronavirus (COVID 19): Key Guidance, Information and Support

30 Mar, 2020 | 01:45h | UTC

Primary care & Coronavirus (COVID 19): key guidance, information and support – Medium

Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care – The BMJ

 

Related Commentary on Twitter

 


A War on Two Fronts: Cancer Care in the Time of COVID-19

30 Mar, 2020 | 01:51h | UTC

A War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine

Related Guidelines: COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence AND Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network

 


Video: Coronavirus (COVID-19) Update: Fairly Rationing ICU Care

30 Mar, 2020 | 01:30h | UTC

Coronavirus (COVID-19) Update: Fairly Rationing ICU Care – JAMA

 


COVID-19 and Renin-Angiotensin System Blockers

30 Mar, 2020 | 02:00h | UTC

Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers – Hypertension AND Commentary: COVID-19 alert: Heart and kidney patients should keep taking their medicines – University of Miami Miller School of Medicine

Related Guidelines: HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use AND Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology

Related Article: Is There an Association Between COVID-19 Mortality and the Renin-Angiotensin System—a Call for Epidemiologic Investigations – Clinical Infectious Diseases

 


The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19)

30 Mar, 2020 | 01:33h | UTC

The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19) – JAMA

 


Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington

30 Mar, 2020 | 01:27h | UTC

Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington – New England Journal of Medicine

See also: Defining the Epidemiology of Covid-19 — Studies Needed – New England Journal of Medicine

Related Guidelines: Infection Prevention and Control guidance for Long-Term Care Facilities in the context of COVID-19 – World Health Organization (PDF) AND Preparing for COVID-19: Long-term Care Facilities, Nursing Homes – Centers for Disease Control and Prevention

Related Review: Coronavirus Disease 2019 in Geriatrics and Long‐term Care: The ABCDs of COVID‐19 – Journal of the American Geriatrics Society

Related Article: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report (free)

 


Review: Potential Effects of Coronaviruses on the Cardiovascular System

30 Mar, 2020 | 01:41h | UTC

Potential Effects of Coronaviruses on the Cardiovascular System: A Review – JAMA Cardiology

Editorial: Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality

Related Articles: Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China – JAMA Cardiology AND Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology

Commentary: A Heart Attack? No, It Was the Coronavirus – The New York Times

 


Study: Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility

30 Mar, 2020 | 01:22h | UTC

Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: The Role of Asymptomatic and Presymptomatic in Spread of COVID-19 – Penn State Food Safety AND For Nursing Homes, Symptoms Aren’t Enough to Tell Who’s Sick – Associated Press

 


New Report: The Global Impact of COVID-19 and Strategies for Mitigation and Suppression

27 Mar, 2020 | 04:10h | UTC

Report 12: The Global Impact of COVID-19 and Strategies for Mitigation and Suppression – Imperial College London

See also: Summary

Commentaries: Coronavirus: ‘Act early to save more than 30 million lives’ – BBC AND Study sees ‘severe and acute’ emergency for world in coronavirus pandemic – Reuters

 

Related Commentary on Twitter

 


Must-see Video! Perspectives on the Pandemic with Dr. John Ioannidis

27 Mar, 2020 | 04:03h | UTC

Perspectives on the Pandemic with Dr. John Ioannidis

Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)

 


IHME Report: US Hospitals Could Be Overwhelmed in the Second Week of April by Demand for ICU Beds, and US Deaths Could Total 81,000 by July

27 Mar, 2020 | 04:05h | UTC

News Release: New COVID-19 Forecasts: US Hospitals Could Be Overwhelmed in the Second Week of April by Demand for ICU Beds, and US Deaths Could Total 81,000 by July – Institute for Health Metrics and Evaluation

Abstract: Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator days and deaths by US state in the next 4 months – Institute for Health Metrics and Evaluation

Preprint: Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator days and deaths by US state in the next 4 months (PDF)

Commentaries: A new report warns that the coronavirus pandemic will overwhelm US hospitals and kill 81,000 people by July – Business Insider AND Coronavirus could kill 81,000 in U.S., subside in June – Washington University analysis – Reuters

 


Mathematics of Life and Death: How Disease Models Shape National Shutdowns and Other Pandemic Policies

27 Mar, 2020 | 04:01h | UTC

Mathematics of life and death: How disease models shape national shutdowns and other pandemic policies – Science

See also: How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian

 


Analysis: Managing Mental Health Challenges Faced by Healthcare Workers During Covid-19 Pandemic

27 Mar, 2020 | 03:55h | UTC

Managing mental health challenges faced by healthcare workers during covid-19 pandemic – The BMJ

Related Study: Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 – JAMA Network Open AND Commentary: Survey Finds COVID-19 Takes Heavy Psychological Toll on Health Care Workers – Psychiatric News Alert

 


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