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Infectious Diseases (all articles)

Randomized Trial: CPR–Guided Short Antibiotic Treatment Duration for Uncomplicated Gram-Negative Bacteremia

3 Jun, 2020 | 03:35h | UTC

Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)

 


[Abstract Only] Randomized Trial: 39·0°C vs. 38·5°C Ear Temperature as Fever Limit in Children with Neutropenia Undergoing Chemotherapy for Cancer

3 Jun, 2020 | 03:34h | UTC

39·0°C versus 38·5°C ear temperature as fever limit in children with neutropenia undergoing chemotherapy for cancer: a multicentre, cluster-randomised, multiple-crossover, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

 


Meta-Analysis: Physical Distancing, Face Masks, and Eye Protection to Prevent Transmission of COVID-19

2 Jun, 2020 | 05:12h | UTC

Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis – The Lancet

Commentaries: Most comprehensive study to date provides evidence on optimal physical distancing, face masks, and eye protection to prevent spread of COVID-19 – The Lancet AND Physical distancing, face masks, and eye protection for prevention of COVID-19 – The Lancet AND Medical Workers Should Use Respirator Masks, Not Surgical Masks – The New York Times AND Expert reaction to review of optimal physical distancing, face masks, and eye protection to prevent spread of COVID-19 – Science Media Centre AND Evidence supports physical distancing, masks, and eye protection to help prevent COVID-19 – McMaster University AND Social distancing and masks reduce risk of getting Covid-19, review finds – CNN

 


Anthony Fauci on Covid-19 Reopenings, Vaccines, and Moving at ‘Warp Speed’

2 Jun, 2020 | 05:02h | UTC

Anthony Fauci on Covid-19 reopenings, vaccines, and moving at ‘warp speed’ – STAT

 


Viewpoint: Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

2 Jun, 2020 | 05:03h | UTC

Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection – JAMA

 


Remdesivir Shows Modest Improvement in Moderate COVID-19 Patients

2 Jun, 2020 | 04:59h | UTC


CT in Covid-19: A Systematic Review of Chest CT Findings

2 Jun, 2020 | 04:56h | UTC

CT in coronavirus disease 2019 (COVID-19): a systematic review of chest CT findings in 4410 adult patients – European Radiology

 


Covid-19 Podcast: ACTT-1, Triple Therapy, PCR, Serology

2 Jun, 2020 | 04:55h | UTC

#217 COVID Cakes the Fourth: ACTT-1, Triple Therapy, PCR, Serology – The Curbsiders Internal Medicine Podcast

See also: Episode List

 


Cohort Study: Mortality and Pulmonary Complications in Surgical Patients with Covid-19

1 Jun, 2020 | 04:02h | UTC

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study – The Lancet

Commentaries: Mitigating the risks of surgery during the COVID-19 pandemic – The Lancet AND COVID-19 patients who undergo surgery are at increased risk of postoperative death – University of Birmingham AND Clinicians must carefully balance risk of complications linked to SARS-CoV2 infection with risks of delaying surgery – The Lancet

 


An Open Letter to Mehra et al and The Lancet

1 Jun, 2020 | 03:58h | UTC

An open letter to Mehra et al and The Lancet – Zenodo

See also: Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere – The Scientist AND A Study Out of Thin Air – Medicine (Un)Censored

 


Perspective: Will Evidence-Based Medicine Survive COVID-19?

1 Jun, 2020 | 03:56h | UTC

Will Evidence-Based Medicine Survive COVID-19? – Boston Review

 


Cohort Studies: Clinical Impact of COVID-19 on Patients with Cancer

1 Jun, 2020 | 04:00h | UTC

Study 1: Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study – The Lancet

Study 2: COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study – The Lancet

Commentaries: Studies highlight COVID-19 impact on cancer patients – CIDRAP AND Cancer, coronavirus are a dangerous mix, new studies find – MedicalXpress AND Cancer, coronavirus are a dangerous mix, new studies find – Associated Press AND Cancer and COVID-19: what do we really know? – The Lancet

Related: Cancer patients and research during COVID-19 pandemic: A systematic review of current evidence – Critical Reviews in Oncology/Hematology

 


Review: Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019

1 Jun, 2020 | 03:55h | UTC

Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review – JAMA Neurology

Commentary: Expert reaction a review and a case study looking at neurological manifestations associated with COVID-19 disease and other coronaviruses – Science Media Centre

Related: A Review of Neurological Complications of COVID-19 – Cureus

 


Editorial: Shielding from Covid-19 Should be Stratified by Risk

29 May, 2020 | 03:34h | UTC

Shielding from covid-19 should be stratified by risk – The BMJ

 


[Abstract Only] Meta-Analysis: Reappraisal of the Treatment Duration of Antibiotic Regimens for Acute Uncomplicated Cystitis in Adult Women

1 Jun, 2020 | 03:31h | UTC

Reappraisal of the treatment duration of antibiotic regimens for acute uncomplicated cystitis in adult women: a systematic review and network meta-analysis of 61 randomised clinical trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Cohort Study: Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection

1 Jun, 2020 | 03:29h | UTC

Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection: A Multicenter, Prospective Observational Cohort Study of 783 Patients – Open Forum Infectious Diseases

 


Study in a Cruise Boat Showed 81% of Patients Infected with Covid-19 were Asymptomatic

29 May, 2020 | 03:31h | UTC

COVID-19: in the footsteps of Ernest Shackleton – Thorax

Commentaries: New Paper Finds Startling Number Of Asymptomatic Covid-19 Carriers – Forbes AND Asymptomatic COVID-19 cases may be more common than suspected – NBC News AND Cruise ship study hints at many ‘silent’ COVID-19 infections – The BMJ

 


Opinion: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic

29 May, 2020 | 03:27h | UTC

Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic – JAMA

 


Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity

29 May, 2020 | 03:26h | UTC

Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity – JAMA

 


42% of Patients with Covid-19 Asymptomatic in Study from China

29 May, 2020 | 03:29h | UTC

Comparison of Clinical Characteristics of Patients with Asymptomatic vs Symptomatic Coronavirus Disease 2019 in Wuhan, China – JAMA Network Open

Commentaries: 40% of COVID-19 patients may be asymptomatic as disease progresses – UPI AND How Common Are Asymptomatic Cases of COVID-19? – U.S News

 


Perspective: For Seniors, COVID-19 Sets Off A Pandemic Of Despair

29 May, 2020 | 03:23h | UTC

For Seniors, COVID-19 Sets Off A Pandemic Of Despair – Kaiser Health News

 


Wastewater Testing Gains Traction as a Covid-19 Early Warning System

29 May, 2020 | 03:22h | UTC

Wastewater testing gains traction as a Covid-19 early warning system – STAT

Related: SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area – Water Research AND New Research Examines Wastewater to Detect Community Spread of Covid-19

 


Observational Study: Many Patients with Covid-19 in the ICU Develop Thromboembolism Despite Routine Prophylaxis

29 May, 2020 | 03:17h | UTC

Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019 – Critical Care Medicine

 


Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development

29 May, 2020 | 03:19h | UTC

Ethical guidelines for deliberately infecting volunteers with COVID-19 – Journal of Medical Ethics

Commentary: COVID-19 vaccine development: New guidelines for ethical approach to infecting trial volunteers – University of Warwick

Related: Challenge trials can speed development of a Covid-19 vaccine. Planning for them needs to start now – STAT AND AstraZeneca says it may consider exposing vaccine trial participants to virus – Reuters

 


Ethical Guidelines for COVID-19 Tracing Apps

29 May, 2020 | 03:18h | UTC

Ethical guidelines for COVID-19 tracing apps – Nature

 


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