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Infectious Diseases (all articles)

Retrospective Study | Clinical features and management of individuals admitted to hospital with monkeypox

13 Jan, 2023 | 13:33h | UTC

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study – The Lancet Infectious Diseases

 


Rapid review on monkeypox policies among the G20 nations: relevance to policy and practitioner

13 Jan, 2023 | 13:34h | UTC

Rapid review on monkeypox policies among the G20 nations: relevance to policy and practitioner – F1000 Research

 


Study suggests delivering high concentrations of antibiotics into the implantation site is feasible for infections in implanted CV electronic devices

13 Jan, 2023 | 13:26h | UTC

Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: 

Direct Delivery of Antibiotics to CV Device Pocket Infections Appears Promising – TCTMD

Regional Antibiotics for Implanted Cardiovascular Electronic Device Infections – American College of Cardiology

 


Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease

13 Jan, 2023 | 13:25h | UTC

Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study – Gut

News Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom

Commentaries: 

Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP

Antibiotic Exposure Positively Linked to IBD Development – HealthDay

 

Commentary on Twitter

 


An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants

13 Jan, 2023 | 13:10h | UTC

News Release: An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants – American Association for Cancer Research

Original Article: Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting – Clinical Cancer Research

Commentary: Study Finds Posoleucel Demonstrated Antiviral Efficacy and Safety Against Viral Infections Following Allogeneic Stem Cell Transplantation – The ASCO Post

 


RCT | A 24-week, all-oral regimen for rifampin-resistant tuberculosis

12 Jan, 2023 | 13:27h | UTC

A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis – New England Journal of Medicine

Commentary: Trial results show superiority of shorter, all-oral treatment for drug-resistant TB – CIDRAP

 


WHO consolidated guidelines on tuberculosis | Drug-resistant tuberculosis treatment, 2022 update

12 Jan, 2023 | 13:30h | UTC

WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update – World Health Organization

See also:

WHO consolidated guidelines on tuberculosis: module 1: prevention: tuberculosis preventive treatment

WHO consolidated guidelines on tuberculosis: module 2: screening: systematic screening for tuberculosis disease

WHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update

WHO consolidated guidelines on tuberculosis: module 5: management of tuberculosis in children and adolescents

 


RCT | Early treatment with Molnupiravir did not reduce hospitalizations in high-risk adults with COVID-19

12 Jan, 2023 | 13:24h | UTC

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial – The Lancet

Commentaries: 

Molnupiravir does not reduce COVID-19 hospitalisations or deaths in vaccinated, high risk people – National Institute for Health and Care Research

Molnupiravir doesn’t cut Omicron hospitalization, death but can speed recovery – CIDRAP

 


The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic

12 Jan, 2023 | 13:26h | UTC

The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic – Journal of Antimicrobial Chemotherapy

 


RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication

12 Jan, 2023 | 13:06h | UTC

Second-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


SR | Interventions for the eradication of methicillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis

12 Jan, 2023 | 13:04h | UTC

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis – Cochrane Library

 


Review | Early diagnosis and prevention of infections in cirrhosis

12 Jan, 2023 | 12:47h | UTC

Early Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease

 


Statement | Pre-procedure and pre-admission COVID-19 testing no longer recommended for asymptomatic patients

11 Jan, 2023 | 14:36h | UTC

News Release: Pre-Procedure and Pre-Admission COVID-19 Testing No Longer Recommended for Asymptomatic Patients – Infection Control & Hospital Epidemiology

Recommendation Statement: Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: Challenges and considerations – Infection Control & Hospital Epidemiology

Commentary: Infectious disease board recommends hospitals stop screening asymptomatic patients for Covid-19 – STAT

Related: Routine pre-operative Covid testing in elective surgeries: Is it worth it? – American Journal of Surgery

 


Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis

11 Jan, 2023 | 14:30h | UTC

Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis – Circulation

News Release: Researchers study immune response, proteins in blood of young adults who develop rare complication after COVID vaccination – Mass General Brigham

Commentary: Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine – News Medical

 


Review | Durability of vaccine-induced and natural immunity against COVID-19

11 Jan, 2023 | 14:29h | UTC

Durability of Vaccine-Induced and Natural Immunity Against COVID-19: A Narrative Review – Infectious Diseases and Therapy

 


Monkeypox (hMPXV infection): a practical review

11 Jan, 2023 | 14:25h | UTC

Monkeypox (hMPXV infection): A practical review – American Journal of Medicine

 


WHO Interim Guidance | Surveillance, case investigation and contact tracing for mpox (monkeypox)

10 Jan, 2023 | 14:45h | UTC

Surveillance, case investigation and contact tracing for mpox (monkeypox): interim guidance, 22 December 2022 – World Health Organization

 


MRI of acute neck infections: evidence summary and pictorial review

10 Jan, 2023 | 14:33h | UTC

MRI of acute neck infections: evidence summary and pictorial review – Insights into Imaging

 


WHO updates recommendations on HPV vaccination schedule

9 Jan, 2023 | 14:57h | UTC

News Release: WHO updates recommendations on HPV vaccination schedule – World Health Organization

Guideline: Human papillomavirus vaccines: WHO position paper, December 2022 – World Health Organization

Commentaries: 

WHO Recommends One HPV Vaccine Dose Instead of Two; Move Should Help Expand Coverage – Health Policy Watch

WHO supports 1-dose HPV vaccine strategy – CIDRAP

 

Commentary on Twitter

 


RCT | VV116 vs. Nirmatrelvir–Ritonavir for oral treatment of Covid-19

9 Jan, 2023 | 14:50h | UTC

VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19 – New England Journal of Medicine

Commentaries: 

Study could pave way for new antiviral, as China grapples with Covid wave – STAT

Chinese oral COVID-19 drug equally effective with Paxlovid: study

VV116 Noninferior to Nirmatrelvir-Ritonavir for COVID-19 – HealthDay

 

Commentary on Twitter

 


The WHO estimates of excess mortality associated with the COVID-19 pandemic

9 Jan, 2023 | 14:48h | UTC

The WHO estimates of excess mortality associated with the COVID-19 pandemic – Nature

Commentary: Pandemic’s Two-Year Global Death Toll May Be Close to 15 Million – HealthDay

 


RCTs | Vaccines for Zaire Ebola virus disease.

16 Dec, 2022 | 13:46h | UTC

Randomized Trial of Vaccines for Zaire Ebola Virus Disease – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Ebola vaccine regimens safe, immunogenic in adults and children – NIH News Releases

Commentaries: 

Ebola vaccine strategies show safety and immune response – CIDRAP

Trial on safety and immunogenicity of Ebola vaccines yields promising results – Institut National de la Sante et de la Recherche Medicale

 

Commentary on Twitter

 


RCT | Efficacy and safety of azithromycin vs. placebo to treat lower respiratory tract infections associated with low procalcitonin.

16 Dec, 2022 | 13:30h | UTC

Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text) 

Commentary: Study Evaluates Biomarker to Help Curb Unnecessary Antibiotic Use: Placebo Worse Than Antibiotics After 5 Days, But Similar at Day 11 – Duke Health

 

Commentary on Twitter

 


Review | Human papillomavirus vaccination and cervical cancer risk.

16 Dec, 2022 | 13:26h | UTC

Human papillomavirus vaccination and cervical cancer risk – The BMJ

 


BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022.

15 Dec, 2022 | 13:52h | UTC

BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022 – HIV Medicine

Related: Consensus Recommendations | Antiretroviral drugs for treatment and prevention of HIV infection in adults.

 


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