Infectious Diseases (all articles)
COVID-19 and mRNA vaccines—first large test for a new approach
4 Sep, 2020 | 02:08h | UTCCOVID-19 and mRNA Vaccines—First Large Test for a New Approach – JAMA
Forty postmortem examinations in COVID-19 Patients: Two distinct pathologic phenotypes and correlation with clinical and radiologic findings
4 Sep, 2020 | 02:05h | UTC
Commentary on Twitter
Our COVID autopsy study is now online! We describe 2 distinct pathologic phenotypes and correlate with clinical and radiologic data. So proud of this team! 💕@ColumbiaPath @AJCPjournal #pulmpath #pathology #autopsy #NYC #COVID19 #covid https://t.co/f3xhc0v1si
— Simona De Michele, MD (@SDeMicheleMD) September 3, 2020
Opinion: Herd immunity is not a strategy
4 Sep, 2020 | 02:09h | UTCHerd Immunity Is Not a Strategy – The Atlantic
Challenges in evaluating SARS-CoV-2 vaccines during the COVID-19 pandemic
4 Sep, 2020 | 02:06h | UTC
Coalition Covid-19 Brazil – Randomized trial: Dexamethasone improves outcomes in patients with Acute Respiratory Distress Syndrome and COVID-19
3 Sep, 2020 | 11:24h | UTCEditorial: Corticosteroids in COVID-19 ARDS: Evidence and Hope During the Pandemic
Related studies: Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial – JAMA AND Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial – JAMA
Commentary: Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients – NPR
Commentary on Twitter
In this RCT, IV #dexamethasone increased the number of ventilator-free days by day 28 vs standard care alone among patients with #COVID19 and moderate or severe ARDS https://t.co/RA9G6LVRlz @ICURevisited @FlaviaSepsis @israelmaia16
— JAMA (@JAMA_current) September 2, 2020
Video: Corticosteroids for COVID-19 – New Evidence of Benefit
3 Sep, 2020 | 11:21h | UTCCorticosteroids for COVID-19 – New Evidence of Benefit – JAMA
Meta-analysis: Corticosteroids for critically ill patients with COVID-19
3 Sep, 2020 | 11:23h | UTCEditorial: Corticosteroids in COVID-19 ARDS: Evidence and Hope During the Pandemic
Commentaries: Analysis of seven trials finds that corticosteroids reduce risk of death by 20 per cent in critically ill COVID-19 patients – University of Bristol AND Multiple studies confirm steroids can fight severe COVID-19 – MedicalXpress
Commentary on Twitter
1/8 Corticosteroids and COVID19
*Three* RCTs and a new @WHO meta-analysis add to #RECOVERY trial data that corticosteroids reduce mortality in critically ill #COVID19 patientshttps://t.co/H8c46Y5DTm— JAMA (@JAMA_current) September 2, 2020
New WHO Guidance: Corticosteroids for COVID-19
3 Sep, 2020 | 11:20h | UTCCorticosteroids for COVID-19 – World Health Organization
News Release: WHO updates clinical care guidance with corticosteroid recommendations – World Health Organization
Commentaries: The WHO Now Recommends Cheap Steroids As a Life-Saving Treatment for Severe Covid-19 – Gizmodo AND Inexpensive steroids reduce deaths of hospitalized Covid-19 patients, WHO analysis confirms – STAT
Commentary on Twitter
🆕 guideline on use of dexamethasone & other corticosteroids advises:
✅ for oral or intravenous usage in treatment of patients with severe & critical #COVID19
❌ against usage in treatment of non-severe casesMore: https://t.co/eWHzRrYKvO
— World Health Organization (WHO) (@WHO) September 2, 2020
[Preprint] Randomized trial: Tocilizumab does not improve clinical status or mortality in hospitalized patients with COVID-19 pneumonia
3 Sep, 2020 | 11:19h | UTCTocilizumab in Hospitalized Patients With COVID-19 Pneumonia – medRxiv
Covid-19: Study found those younger than 40 had an infection fatality ratio (IFR) of 0.01%; those 60 or older had an IFR of 1.71%
3 Sep, 2020 | 11:18h | UTC
Commentary on Twitter
Age, sex, race affect death risk from #COVID-19. @FSPH_IUPUI study found those younger than 40 had fatality rate of 0.01%; those 60 or older 1.71%—2.5 times greater than #flu https://t.co/oT4BCVbVxe. @jblackburn_phd @aaronecarroll pic.twitter.com/wE6Ti0EG6E
— Annals of Int Med (@AnnalsofIM) September 2, 2020
Virus in the blood can predict severe COVID-19
3 Sep, 2020 | 11:11h | UTCVirus in the blood can predict severe COVID-19 – Karolinska Institutet
Original Study: SARS-CoV-2 RNA in serum as predictor of severe outcome in COVID-19: a retrospective cohort study – Clinical Infectious Diseases
COVID-19 can wreck your heart, even if you haven’t had any symptoms
3 Sep, 2020 | 11:06h | UTCCOVID-19 Can Wreck Your Heart, Even if You Haven’t Had Any Symptoms – Scientific American
IDSA Podcast – Managing patients post-COVID-19: From symptoms to lasting complications
3 Sep, 2020 | 11:08h | UTC
Combining PCR and antibody tests at point of care dramatically increases COVID-19 detection
3 Sep, 2020 | 11:10h | UTCOriginal Study: Combined point of care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G Spike Variant – Cell Reports Medicine
Fauci says COVID vaccine trials could end early if results are overwhelming
3 Sep, 2020 | 11:02h | UTCFauci Says COVID Vaccine Trials Could End Early If Results Are Overwhelming – Kaiser Health News
Getting ready for the Covid-19 pandemic: Experience of a Brazilian hospital
3 Sep, 2020 | 11:00h | UTCGetting Ready for the Covid-19 Pandemic: Experience of a Brazilian Hospital – NEJM Catalyst
23 bus passengers contracted coronavirus from 1 infected person. No one was wearing a mask.
2 Sep, 2020 | 10:09h | UTCOriginal Study: Community Outbreak Investigation of SARS-CoV-2 Transmission Among Bus Riders in Eastern China – JAMA Internal Medicine
Commentary on Twitter
Outbreak on a bus in China is offering new evidence about SARSCoV2's airborne spread. A person on a poorly ventilated vehicle infected nearly 2 doz people even tho many weren't sitting nearby. Conclusion: mere breathing can send micro-droplets into the air https://t.co/plxzOrZLAT
— delthia ricks 🔬 (@DelthiaRicks) September 1, 2020
New #OpenWho Course: Occupational health and safety for health workers in the context of COVID-19
2 Sep, 2020 | 10:11h | UTC
Study: Face shields, masks with valves ineffective against COVID-19 spread
2 Sep, 2020 | 09:55h | UTCFace Shields, Masks with Valves Ineffective Against COVID-19 Spread – American Institute of Physics
Original Study: Visualizing droplet dispersal for face shields and masks with exhalation valves – Physics of Fluids
How many people has the coronavirus killed?
2 Sep, 2020 | 09:59h | UTCHow many people has the coronavirus killed? – Nature
Probable evidence of fecal aerosol transmission of SARS-CoV-2 in a high-rise building
2 Sep, 2020 | 10:07h | UTC
Commentary on Twitter
NEW❗ #Fecal aerosol transmission may have caused the community outbreak of #COVID19 in this high-rise building researchers investigated https://t.co/5TAJqSq0I0. pic.twitter.com/IbBOwzI1az
— Annals of Int Med (@AnnalsofIM) September 1, 2020
Humoral immune response to SARS-CoV-2 in Iceland
2 Sep, 2020 | 09:57h | UTCHumoral Immune Response to SARS-CoV-2 in Iceland – New England Journal of Medicine
Editorial: The Power of Antibody-Based Surveillance
Commentary on Twitter
I would never have guessed that IFR would become one of the most controversial topics of 2020
The IFR in today's @NEJM publication of the Iceland experience was 0.3% https://t.co/bkub1TcazK
The IFR in the preprint meta-analysis by satan was 0.27%
🤷♂️ pic.twitter.com/arz3cCKRvA— Vinay Prasad MD MPH (@VPrasadMDMPH) September 1, 2020
Meta-analysis: Clinical manifestations, risk factors, and maternal and perinatal outcomes of Covid-19 in pregnancy
2 Sep, 2020 | 09:52h | UTC
U.S. advisory group lays out detailed recommendations on how to prioritize Covid-19 vaccine
2 Sep, 2020 | 09:46h | UTCU.S. advisory group lays out detailed recommendations on how to prioritize Covid-19 vaccine – STAT
#ESCCongress – [Not Published Yet] First randomized trial backs safety of ACE Inhibitors and ARBs in COVID-19 patients
2 Sep, 2020 | 09:48h | UTCNews Release: First randomised trial backs safety of common heart drugs in COVID-19 patients – European Society of Cardiology
Commentary on Twitter
Dr. Renato Lopes presents the BRACE CORONA trial: in patients hospitalized with COVID-19, suspending ACEI/ARB therapy for 30 days did not impact the number of days alive and out of hospital.
Full slide deck: https://t.co/avSK41bGSj#ESCCongress pic.twitter.com/2p0FH9U2RG
— C. Michael Gibson MD (@CMichaelGibson) September 1, 2020


