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Infectious Diseases (all articles)

Case-control study: COVID-19-associated stroke is associated with worse outcomes and increased mortality

12 Nov, 2020 | 09:24h | UTC

Characteristics and outcomes of COVID-19-associated stroke: a UK multicentre case-control study – Journal of Neurology, Neurosurgery & Psychiatry

Commentary: Risk of death, disability after stroke much higher for COVID-19 patients – Cardiovascular Business

 


Review for the public on the different kinds of COVID-19 tests. It covers the differences and similarities between molecular, antigen, and serologic tests.

12 Nov, 2020 | 09:19h | UTC

What Are All the Different Kinds of COVID-19 Tests? – Johns Hopkins Bloomberg School of Public Health

 


Wearing cloth or disposable surgical face masks has no effect on vigorous exercise performance in healthy individuals

12 Nov, 2020 | 09:21h | UTC

Wearing of Cloth or Disposable Surgical Face Masks has no Effect on Vigorous Exercise Performance in Healthy Individuals – International Journal of Environmental Research and Public Health

Commentary: Face masks don’t hinder breathing during exercise, study finds – University of Saskatchewan

 


Why do COVID death rates seem to be falling? Correct use of corticosteroids, hard-won experience, younger patients, and reduced strain on hospitals are all possibilities

12 Nov, 2020 | 09:16h | UTC

Why do COVID death rates seem to be falling? – Nature

 


[Preprint] Validation of home oxygen saturation as a marker of clinical deterioration in patients with suspected COVID-19: Even small deflections in oxygen saturations of 1-2% below 96% confer an increased mortality risk.

12 Nov, 2020 | 09:18h | UTC

Validation of home oxygen saturations as a marker of clinical deterioration in patients with suspected COVID-19 – medRxiv

 

Commentary on Twitter

 


Opinion: “Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism. Vaccine science by press release has to stop”

11 Nov, 2020 | 09:25h | UTC

Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism – Vox

Related commentaries: Champagne and questions greet first data showing that a COVID-19 vaccine works – Science AND 90% efficacy for Pfizer’s COVID-19 mRNA vaccine is striking. But we need to wait for the full data – The Conversation

See also: Science by press release: When the story gets ahead of the science – CNN

 


[Preprint] A machine learning study of 534,023 Medicare beneficiaries with COVID-19: Implications for personalized risk prediction to identify candidates for early vaccine and therapeutics allocation.

12 Nov, 2020 | 09:15h | UTC

A Machine Learning Study of 534,023 Medicare Beneficiaries with COVID-19: Implications for Personalized Risk Prediction – medRxiv

Commentary: Largest-to-Date COVID Mortality Study Released – MedPage Today (free registration required)

 


Pfizer vaccine: What an ‘efficacy rate above 90%’ really means

11 Nov, 2020 | 09:23h | UTC

Pfizer vaccine: what an ‘efficacy rate above 90%’ really means – The Conversation

 


Cluster randomized trial: Mass distribution of azithromycin to preschool children in sub-Saharan Africa increases azithromycin resistance by 7-fold, also causing resistance to nonmacrolide antibiotics

12 Nov, 2020 | 09:13h | UTC

Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution – New England Journal of Medicine

 


Pfizer’s ultra-cold vaccine could be difficult to distribute

11 Nov, 2020 | 09:22h | UTC

Pfizer’s ultra-cold vaccine could be difficult to distribute – The Conversation

 


Covid-19: Reopening places such as restaurants, gyms, hotels, cafes, and religious organizations are predicted to cause the largest increase in infections

11 Nov, 2020 | 09:26h | UTC

Mobility network models of COVID-19 explain inequities and inform reopening – Nature

Commentaries: Restaurants and gyms were spring ‘superspreader’ sites. Occupancy limits could control Covid, new study predicts  – STAT AND How to stop restaurants from driving COVID infections – Nature AND Covid Superspreader Risk Is Linked to Restaurants, Gyms, Hotels – Bloomberg AND Covid-19 modeling study suggests which places may have highest risk of spread — but occupancy limits can help – CNN

 

Commentary on Twitter

 


Study: N95 masks with exhalation valves do not work

11 Nov, 2020 | 09:20h | UTC

Flow visualization of an N95 respirator with and without an exhalation valve using schlieren imaging and light scattering – Physics of Fluids

Commentary: N95 Masks With Exhalation Valves Don’t Slow The Spread Of Covid-19 – Forbes

 

Commentary on Twitter

 


Derivation and validation of the HA2T2 (Hypoxia, Age, Troponin) COVID‐19 mortality risk score

11 Nov, 2020 | 09:18h | UTC

Troponin and Other Biomarker Levels and Outcomes Among Patients Hospitalized with COVID‐19: Derivation and Validation of the HA2T2 COVID‐19 Mortality Risk Score – Journal of the American Heart Association

 

Commentary on Twitter

 


[Not Published Yet] Randomized trial: Long-acting injectable drug every 8 weeks is highly effective in preventing HIV acquisition in women

11 Nov, 2020 | 09:17h | UTC

Trial results reveal that long-acting injectable cabotegravir as PrEP is highly effective in preventing HIV acquisition in women – World Health Organization

Commentary: NIH study finds long-acting injectable drug prevents HIV acquisition in cisgender women – NIH News Releases

 


News Release [Not Published Yet]: Vaccine candidate 90% effective against Covid-19 according to manufacturer

10 Nov, 2020 | 09:41h | UTC

News Release: Pfizer and Biontech announce vaccine candidate against Covid-19 achieved success in first interim analysis from phase 3 study

Commentaries: What Pfizer’s landmark COVID vaccine results mean for the pandemic – Nature AND Covid-19: Vaccine candidate may be more than 90% effective, interim results indicate – The BMJ AND Covid vaccine: First ‘milestone’ vaccine offers 90% protection – BBC AND Hopes rise for end of pandemic as Pfizer says vaccine is 90% effective – The Guardian AND Four reasons for encouragement based on Pfizer’s Covid-19 vaccine results – STAT AND Expert reaction to Pfizer and BioNTech reporting interim results from phase 3 COVID-19 vaccine trial – Science Media Centre

 


Another study shows hydroxychloroquine does not benefit adults hospitalized with COVID-19

10 Nov, 2020 | 09:39h | UTC

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial – JAMA

Editorial: Misguided Use of Hydroxychloroquine for COVID-19: The Infusion of Politics Into Science

Commentary: Hydroxychloroquine does not benefit adults hospitalized with COVID-19 – NIH News Releases

 


Patients with Covid-19 and myocardial injury have increased in-hospital mortality, particularly if echocardiographic abnormalities are present

10 Nov, 2020 | 09:37h | UTC

Characterization of Myocardial Injury in Patients With COVID-19 – Journal of the American College of Cardiology

Commentary: Study identifies cardiac structural damage experienced by COVID-19 patients – Mount Sinai Health System / News Medical

 


Report: Large cluster of cases during a long flight shows seating proximity was strongly associated with infection risk

10 Nov, 2020 | 09:38h | UTC

Transmission of SARS-CoV 2 During Long-Haul Flight – Emerging Infectious Diseases

Related studies: In-Flight Transmission of SARS-CoV-2 – Emerging Infectious Diseases AND A large national outbreak of COVID-19 linked to air travel, Ireland, summer 2020 – Eurosurveillance

Commentaries: Coronavirus can spread on airline flights, two studies show – CNN AND Do Masks On Plane Flights Really Cut Your Risk Of Catching COVID-19? – NPR AND Is it worth the risk? A guide to navigating holiday travel during the pandemic University of Texas Health Science Center at Houston

 


Case reports: Multidrug-resistant Candida auris infections in critically ill Covid-19 patients

10 Nov, 2020 | 09:33h | UTC

Multidrug-Resistant Candida auris Infections in Critically Ill Coronavirus Disease Patients, India, April–July 2020 – Emerging Infectious Diseases

Commentaries: Candida auris Infection in COVID-19 Patients – NEJM Journal Watch AND Drug-resistant superbug thriving in hospitals hit hard by COVID-19 – National Geographic

 


In patients hospitalized with COVID-19, right ventricular dilation or dysfunction was independently associated with a >2-fold increase in risk for mortality

10 Nov, 2020 | 09:36h | UTC

Prognostic Utility of Right Ventricular Remodeling Over Conventional Risk Stratification in Patients With COVID-19 – Journal of the American College of Cardiology

Commentaries: Utility of RV Remodeling Over Risk Stratification in COVID-19 – American College of Cardiology AND Damage to heart’s right ventricle predicts a greater chance of death from COVID-19 – Weill Cornell Medical College

 


Aspirin to be investigated as a possible treatment for COVID-19 in the RECOVERY trial

10 Nov, 2020 | 09:35h | UTC

Aspirin to be investigated as a possible treatment for COVID-19 in the RECOVERY trial – University of Oxford

Commentary: Aspirin to be tested as potential COVID-19 drug in UK study – Reuters

 


WHO: Preliminary findings indicate that a SARS-CoV-2 mink-associated variant strain has moderately decreased sensitivity to neutralizing antibodies. The implications are not yet well understood.

9 Nov, 2020 | 01:34h | UTC

SARS-CoV-2 mink-associated variant strain – Denmark – World Health Organization

Commentaries: Spread of mutated coronavirus in Danish mink ‘hits all the scary buttons,’ but fears may be overblown – STAT AND Six countries reported coronavirus on mink farms, WHO says – MedicalXpress AND What’s the science behind mink and coronavirus? – BBC

 


Video: Herd immunity as a coronavirus pandemic strategy

9 Nov, 2020 | 01:32h | UTC

Herd Immunity as a Coronavirus Pandemic Strategy – JAMA

 


What can we expect from new SARS-CoV-2 rapid tests? They promise to aid public health responses to COVID-19, since they can deliver results in a matter of minutes in the field, rather than taking days in clinical diagnostic labs

9 Nov, 2020 | 01:30h | UTC

Coronavirus testing finally gathers speed – Nature

 


[Preprint] Covid-19 vs. Influenza in Kids: Despite negligible fatality, complications including pneumonia, acute respiratory distress syndrome and multi-system inflammatory syndrome were more frequent in children/adolescents with Covid-19 than with influenza

9 Nov, 2020 | 01:27h | UTC

Baseline characteristics, management, and outcomes of 55,270 children and adolescents diagnosed with COVID-19 and 1,952,693 with influenza in France, Germany, Spain, South Korea and the United States: an international network cohort study – medRxiv

 


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