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Infectious Diseases (all articles)

RCT | BCG vaccine not effective for preventing COVID-19 and other respiratory tract infections in older adults

9 Feb, 2023 | 13:53h | UTC

Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial – Clinical Microbiology and Infection

News Release: Tuberculosis vaccine does not protect elderly against COVID-19, finds large Dutch study – University Medical Center Utrecht

 

Commentary on Twitter

 

RCT | Pregnancy and neonatal safety of PrEP for HIV prevention initiated during pregnancy vs. afterwards

9 Feb, 2023 | 13:55h | UTC

Pregnancy and neonatal safety outcomes of timing of initiation of daily oral tenofovir disoproxil fumarate and emtricitabine pre-exposure prophylaxis for HIV prevention (CAP016): an open-label, randomised, non-inferiority trial – The Lancet HIV (link to abstract – $ for full-text)

 

Guidance on the use of convalescent plasma to treat immunocompromised patients with COVID-19

9 Feb, 2023 | 13:50h | UTC

Guidance on the use of convalescent plasma to treat immunocompromised patients with COVID-19 – Clinical Infectious Diseases

 

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

9 Feb, 2023 | 13:26h | UTC

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians – Intensive Care Medicine

 

Commentary on Twitter

 

Review | Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome

8 Feb, 2023 | 12:38h | UTC

Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome – Nature Reviews Cardiology

 

Commentary on Twitter

 

Video | Malaria — Epidemiology, treatment, and prevention

8 Feb, 2023 | 12:37h | UTC

Malaria — Epidemiology, Treatment, and Prevention | NEJM

 

Opinion | Let’s do the Cochrane review of physical measures to reduce the spread of viruses

7 Feb, 2023 | 14:11h | UTC

Let’s Do the Cochrane Review of Physical Measures to Reduce the Spread of Viruses – Sensible Medicine

Original Study: SR | Physical interventions to interrupt or reduce the spread of respiratory viruses

Related: Hospital masking should be optional – Sensible Medicine

 

RCT | Paxlovid did not improve outcomes in hospitalized patients with Covid-19

7 Feb, 2023 | 14:08h | UTC

Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study – The Lancet Regional Health Western Pacific

 

M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients

7 Feb, 2023 | 14:06h | UTC

The Effect of Heparin Full-Dose Anticoagulation on Survival of Hospitalized, Non-critically Ill COVID-19 Patients: A Meta-analysis of High Quality Studies – Lung

Related:

#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Efficacy and safety of heparin full-dose anticoagulation in hospitalized non-critically ill COVID-19 patients: a meta-analysis of multicenter randomized controlled trials – Journal of Thrombosis and Thrombolysis

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 

An analysis of national action plans for antimicrobial resistance—gaps and opportunities in strategies optimizing antibiotic use

7 Feb, 2023 | 13:48h | UTC

An analysis of existing national action plans for antimicrobial resistance—gaps and opportunities in strategies optimising antibiotic use in human populations – The Lancet Global Health

 

Commentary on Twitter

 

Can the future of ID escape the inertial dogma of its past? The exemplars of shorter is better and oral is the new IV

7 Feb, 2023 | 13:34h | UTC

Can the Future of ID Escape the Inertial Dogma of Its Past? The Exemplars of Shorter Is Better and Oral Is the New IV – Open Forum Infectious Diseases

 

Update guidelines for women with HIV who are virally suppressed incorporate breastfeeding their infants as a viable option

6 Feb, 2023 | 13:40h | UTC

Update to Clinical Guidelines for Infant Feeding Supports Shared Decision Making: Clarifying Breastfeeding Guidance for People with HIV – HIV.gov

 

Commentary on Twitter

 

Opinion | Hospital masking should be optional

6 Feb, 2023 | 13:37h | UTC

Hospital masking should be optional – Sensible Medicine

Related: SR | Physical interventions to interrupt or reduce the spread of respiratory viruses

 

Case-control study | Estimation of vaccine effectiveness of CoronaVac and BNT162b2 in patients with SARS-CoV-2 Omicron

6 Feb, 2023 | 13:32h | UTC

Estimation of Vaccine Effectiveness of CoronaVac and BNT162b2 Against Severe Outcomes Over Time Among Patients With SARS-CoV-2 Omicron – JAMA Network Open

 

Commentary on Twitter

 

Guideline | Diagnosis and management of otitis media with effusion in children

6 Feb, 2023 | 13:23h | UTC

Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan – 2022 update – Auris Nasus Larynx

 

Rates of antimicrobial resistance in Helicobacter pylori isolates across the US and Europe

6 Feb, 2023 | 13:12h | UTC

Rates of Antimicrobial Resistance in Helicobacter pylori Isolates From Clinical Trial Patients Across the US and Europe – The American Journal of Gastroenterology

Commentary: Time to ditch clarithromycin for H. pylori? – MDedge

 

Commentary on Twitter

 

The next generation of coronavirus vaccines: a graphical guide

3 Feb, 2023 | 14:18h | UTC

The next generation of coronavirus vaccines: a graphical guide – Nature

 

Review | Current and emerging knowledge of diagnostic imaging in COVID-19

2 Feb, 2023 | 15:04h | UTC

Current and Emerging Knowledge in COVID-19 – Radiology

See also:

Long-term Lung Abnormalities Associated with COVID-19 Pneumonia – Radiology

An Integrated Radiologic-Pathologic Understanding of COVID-19 Pneumonia – Radiology

 

Patients labeled as nonallergic after initial tests for penicillin allergy may develop resensitization afterwards

2 Feb, 2023 | 15:03h | UTC

Resensitization in suspected penicillin allergy – Allergy

Video summary: Resensitisation in suspected penicillin allergy

Commentary: Patients should be retested for penicillin resensitization before being deemed nonallergic – Healio (free registration required)

Related:

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs – JAC-Antimicrobial Resistance

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

Commentary on Twitter

 

Deconstructing the dogma: meta-analysis of adjunctive gentamicin and rifampin in staphylococcal prosthetic valve endocarditis

2 Feb, 2023 | 15:00h | UTC

Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis – Open Forum Infectious Diseases

 

Commentary on Twitter

 

Fungal Nomenclature: managing change is the name of the game

2 Feb, 2023 | 14:59h | UTC

Fungal Nomenclature: Managing Change is the Name of the Game – Open Forum Infectious Diseases

 

Commentary from the author on Twitter (thread – click for more)

https://twitter.com/thefunguskidd/status/1611639451134070784

 

A primer on home infusion administration methods

2 Feb, 2023 | 14:57h | UTC

A Primer on Home Infusion Administration Methods – Open Forum Infectious Diseases

 

M-A | Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis

2 Feb, 2023 | 14:50h | UTC

Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis in adults: A meta-analysis – Journal of Clinical Pharmacy and Therapeutics

 

RCT | Oral minocycline plus rifampicin vs. oral linezolid for complicated skin and skin structure infections caused by MRSA

2 Feb, 2023 | 14:33h | UTC

Oral minocycline plus rifampicin versus oral linezolid for complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: The AIDA open label, randomized, controlled Phase 4 trial – eClinicalMedicine

 

The IDSA Guidelines on the diagnosis of COVID-19: antigen testing

1 Feb, 2023 | 13:37h | UTC

The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Antigen Testing – Clinical Infectious Diseases

 

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