Infectious Diseases (all articles)
A meta-analysis on the role of children in SARS-CoV-2 in household transmission clusters
15 Dec, 2020 | 01:34h | UTCCommentary: Kids likely not driving household COVID-19 outbreaks – CIDRAP
Study: Children and adults equally susceptible to in-home COVID-19 spread, but children generally had less frequent and severe symptoms
15 Dec, 2020 | 01:36h | UTCCommentaries: Study: Kids, adults equally susceptible to in-home COVID-19 spread – CIDRAP AND COVID-19 in Children: Looking Forward, Not Back
Randomized trial: Baricitinib plus remdesivir reduce recovery time in patients with COVID-19
13 Dec, 2020 | 23:31h | UTCBaricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary: Baricitinib plus remdesivir shows promise for treating COVID-19 – NIH News Releases
Commentary on Twitter
Not sure how to interpret a trial for a drug plus Remdesivir vs Remdesivir alone when you don't know if Remdesivir works. @NEJM today for this combo, which has already received FDA EUAhttps://t.co/tpmHPFPJX1 pic.twitter.com/Tmue99oJnV
— Eric Topol (@EricTopol) December 11, 2020
Podcast: Management of Cellulitis
15 Dec, 2020 | 01:20h | UTC
Call for action: Managing the infodemic – A global movement to promote access to health information and mitigate harm from health misinformation among online and offline communities
13 Dec, 2020 | 23:34h | UTCCall for Action: Managing the Infodemic – World Health Organization
See also: Infodemic Management – World Health Organization AND Tips for professional reporting on COVID-19 vaccines – World Health Organization
Meta-analysis: Efficacy and harms of remdesivir for the treatment of COVID-19. “Until stronger evidence emerges, we cannot conclude that remdesivir is efficacious for treating COVID-19”.
13 Dec, 2020 | 23:27h | UTC
Video: Coronavirus vaccine update with Anthony Fauci
13 Dec, 2020 | 23:25h | UTCCoronavirus Vaccine Update With Anthony Fauci – JAMA
A systematic review of corticosteroid treatment for noncritically ill patients with COVID-19 – corticosteroid treatment is not recommended for patients with mild or moderate COVID-19
13 Dec, 2020 | 23:26h | UTC
Fauci says herd immunity possible by fall, ‘normality’ by end of 2021
13 Dec, 2020 | 23:23h | UTCFauci says herd immunity possible by fall, ‘normality’ by end of 2021 – The Harvard Gazette
A doctor on 9 things that could go wrong with the new vaccines – by worrying together, we can prevent much of this from happening
13 Dec, 2020 | 23:21h | UTCA doctor on 9 things that could go wrong with the new vaccines – Vox
WHO calls on world leaders to “honor their pledge” to fund COVID-19 vaccines; South Africa raises specter of “vaccine apartheid”
13 Dec, 2020 | 23:22h | UTC
Just published: Pfizer vaccine confers 95% protection against Covid-19
11 Dec, 2020 | 09:32h | UTCSafety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine – New England Journal of Medicine
Editorial: SARS-CoV-2 Vaccination — An Ounce (Actually, Much Less) of Prevention
Commentary: Pfizer vaccine results published in peer-reviewed journal – MedicalXpress
Related: FDA advisory panel endorses Pfizer/BioNTech Covid-19 vaccine – STAT
Commentary on Twitter (Thread – Click for more)
I read the @pfizer @US_FDA vaccine briefing doc
3 take homes (1 obvious, 2 new takes I haven't seen before)
1. Efficacy is great to prevent #COVID19 & promising for severe illness (this has been said many times before)
Moving on…https://t.co/WLrEpjmuO8
— Anil Makam (@AnilMakam) December 10, 2020
Healthcare workers 7 times as likely to have severe COVID-19 as other workers
11 Dec, 2020 | 09:29h | UTCCommentary: Healthcare workers 7 times as likely to have severe COVID-19 as other workers – BMJ
Commentary on Twitter
Of essential workers, who has the highest risk of severe #COVID19?
Healthcare workforce >7X.
Non-white >8X.https://t.co/ZBUJYccXlT (compared with non-essential workers)
A @uk_biobank study from >120,000 participants
[NB: current issue with link] pic.twitter.com/UZmIO69G4O— Eric Topol (@EricTopol) December 9, 2020
Long Covid: Study shows persistence of symptoms in a third of ambulatory patients 30 to 45 days after diagnosis
11 Dec, 2020 | 09:27h | UTCCommentary: COVID-19: persistent symptoms in one third of cases – Université de Genève
Commentary on Twitter
Study of 669 people who had #COVID19 during the first wave in Switzerland. Of 510 who were followed up for 30-45 days, 32% still had at least one symptom.
Fatigue, shortness of breath, and loss of smell or taste were the most common symptoms. #LongCovidhttps://t.co/pDB6nuZWTn pic.twitter.com/bbt9c3LFXl
— Dr Zoë Hyde (@DrZoeHyde) December 8, 2020
British HIV Association guidelines on the management of gastrointestinal opportunistic infections in people living with HIV
11 Dec, 2020 | 09:16h | UTC
Systematic Review: Probiotics probably make little or no difference for patients with acute infectious diarrhea
10 Dec, 2020 | 08:53h | UTCProbiotics for treating acute infectious diarrhoea – Cochrane Library
Summary: Do probiotics help to treat acute infectious diarrhoea? – Cochrane Library
Observational study: Seasonal malaria chemoprevention in localities in west and central Africa was associated with a remarkable reduction in morbidity and mortality from the disease
10 Dec, 2020 | 08:54h | UTC
Systematic review: Men with COVID-19 have almost three times the risk of requiring ICU admission and a higher risk of death
10 Dec, 2020 | 08:45h | UTCCommentary: Men face ‘almost three times the odds’ of ICU admission for Covid-19, study says – CNN AND Men with COVID-19 three times more likely to need intensive care: study – MedicalXpress
Commentary on Twitter
Men w/ COVID19 are 3 times more likely to need intensive care & are at significantly higher risk of dying from the virus than women. New research analyzed over 3 million confirmed cases from 46 countries and 44 states. 2 links: https://t.co/g9nYKWxzcv
andhttps://t.co/ZOIfSYImWi— delthia ricks 🔬 (@DelthiaRicks) December 9, 2020
UAE says Chinese vaccine 86% effective, offers few details
10 Dec, 2020 | 08:43h | UTCUAE says Chinese vaccine 86% effective, offers few details – Associated Press
See also: China State-Backed Covid Vaccine Has 86% Efficacy, UAE Says – Bloomberg
UK to refine allergy warning on Pfizer vaccine sparked by two adverse reactions
10 Dec, 2020 | 08:41h | UTCUK to refine allergy warning on Pfizer vaccine sparked by two adverse reactions – Reuters
See also: UK probes whether COVID-19 vaccine caused allergic reactions – Associated Press AND NHS told not to give Covid vaccine to those with history of allergic reactions – The Guardian
CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk
9 Dec, 2020 | 08:23h | UTCCDC Releases New Ventilation Guidelines For Indoor Environments To Reduce Covid-19 Risk – Forbes
CDC Guideline: Ventilation
Related podcast: Air Handling Standards for Increasing the Safety of Indoor Spaces During the COVID-19 Pandemic – JAMA
Vast majority of pregnant women with COVID-19 won’t have complications, study finds
10 Dec, 2020 | 08:39h | UTCOriginal study: Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection – JAMA Network Open
Just published: AstraZeneca-Oxford Covid-19 vaccine shows moderate efficacy, but questions remain about the most effective dosing regimen
9 Dec, 2020 | 08:25h | UTCCommentaries: Oxford COVID vaccine paper highlights lingering unknowns about results – Nature AND Detailed data on AstraZeneca-Oxford Covid-19 vaccine show it has moderate efficacy – STAT AND Oxford–AstraZeneca COVID-19 vaccine efficacy – The Lancet AND Oxford COVID-19 vaccine is safe and protects against disease, first published results from phase 3 trials – The Lancet AND Expert reaction to a study on the results of phase 3 human trials of the Oxford/AZ COVID-19 vaccine – Science Media Centre
How rich countries are ‘hoarding’ the world’s vaccines, in charts
10 Dec, 2020 | 08:40h | UTCHow Rich Countries Are ‘Hoarding’ The World’s Vaccines, In Charts – NPR
See also: How COVID vaccines are being divvied up around the world – Nature AND Rich countries hoarding Covid vaccines, says People’s Vaccine Alliance – BBC AND Amnesty: rich countries have bought too many COVID-19 vaccines – Reuters
“COVID-19: when are you most infectious?” This commentary from the authors of a recent meta-analysis highlights the findings that infectiousness peaks within the first 5 days of symptom onset
10 Dec, 2020 | 08:38h | UTCCOVID-19: when are you most infectious? – The Conversation
Original study and commentaries: Meta-analysis: SARSCoV2 most contagious within the first 5 days of symptom onset