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Infectious Diseases (all articles)

RECOVERY trial: No Benefit from convalescent plasma in hospitalized patients with Covid-19

17 Jan, 2021 | 22:26h | UTC

RECOVERY trial closes recruitment to convalescent plasma treatment for patients hospitalised with COVID-19

Commentary: Covid: ‘Convalescent plasma no benefit to hospital patients’ – BBC

 

WHO: Infection prevention and control guidance for long-term care facilities in the context of COVID-19 update

17 Jan, 2021 | 22:24h | UTC

Infection prevention and control guidance for long-term care facilities in the context of COVID-19 update – World Health Organization

 

Characterization of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data

17 Jan, 2021 | 22:23h | UTC

Characterisation of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data – The Lancet Respiratory Medicine

 

[In Portuguese] Commentary from the author on Twitter (thread – click for more)

 

Johnson & Johnson publishes early data for its Covid-19 vaccine candidate

17 Jan, 2021 | 22:22h | UTC

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine – New England Journal of Medicine

Commentaries: Johnson & Johnson Publishes Early Data For Its Covid-19 Vaccine Candidate. The Vaccine Is A Few Months Behind The MRNA Options But May Eventually Offer Advantage AND Data fuel debate over whether J&J’s one-dose Covid vaccine will measure up – STAT

 

Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination

17 Jan, 2021 | 22:21h | UTC

Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination – The BMJ

See also: Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail

 

Returning to physical activity after Covid-19

17 Jan, 2021 | 22:19h | UTC

Returning to physical activity after covid-19 – The BMJ

Commentary: Returning to physical activity after a Covid-19 infection – Medical Centre

 

Commentaries on Twitter

 

Alarming COVID variants show vital role of genomic surveillance

17 Jan, 2021 | 22:18h | UTC

Alarming COVID variants show vital role of genomic surveillance – Nature

 

Commentary on Twitter

 

Contradicting early research, 2 new MRI studies show lower degrees of myocarditis in athletes recovered from COVID-19

17 Jan, 2021 | 22:14h | UTC

Study 1: Evaluation for Myocarditis in Competitive Student Athletes Recovering From Coronavirus Disease 2019 With Cardiac Magnetic Resonance Imaging – JAMA Cardiology AND Commentaries: Screening Athletes for Myocarditis With Cardiac Magnetic Resonance Imaging After COVID-19 Infection—Lessons From an English Philosopher – JAMA Cardiology AND Low Prevalence of Myocarditis in Athletes Recovered from COVID-19 – docwire News

Study 2: Cardiac MRI Shows Lower Degrees of Myocarditis in Athletes Recovered From COVID-19 – Circulation AND Commentaries: Cardiac MRI shows lower degrees of myocarditis in athletes recovered from COVID-19 – Vanderbilt University Medical Center AND Heart damage less common among athletes who recover from COVID-19 than previously believed, cardiologists find – Cardiovascular Business

 

Herd immunity by infection is not an option

17 Jan, 2021 | 22:16h | UTC

Herd immunity by infection is not an option – Science

 

CDC Study: Performance of an antigen-based test for asymptomatic and symptomatic SARS-CoV-2

17 Jan, 2021 | 22:10h | UTC

Performance of an Antigen-Based Test for Asymptomatic and Symptomatic SARS-CoV-2 Testing at Two University Campuses — Wisconsin, September–October 2020 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 

Meta-analysis: Prophylactic macrolides beneficial for patients with COPD with frequent exacerbations

17 Jan, 2021 | 22:09h | UTC

Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta‐analysis – Cochrane Library

Summary: Prophylactic antibiotics for people with COPD – Cochrane Library

 

Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection

17 Jan, 2021 | 22:00h | UTC

Proton pump inhibitor use and risk for recurrent Clostridioides difficile infection: A systematic review & meta-analysis – Clinical Microbiology and Infection

 

Randomized trial: In patients hospitalized with community-acquired pneumonia, adjunctive oral dexamethasone reduced the length of stay and ICU admissions, with no difference in mortality rates

17 Jan, 2021 | 21:58h | UTC

Adjunctive treatment with oral dexamethasone in non-ICU patients hospitalised with community-acquired pneumonia: A randomised clinical trial – European Respiratory Journal (link to abstract – $ for full-text)

 

Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

17 Jan, 2021 | 21:50h | UTC

Long-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection – Gastroenterology (link to abstract – $ for full-text)

Commentary: Fecal Transplants Safe Long Term for Recurrent C. Diff — But new-onset conditions post-fecal microbiota transplantation need further study – MedPage Today (free registration required)

 

Systematic review: Insufficient evidence to recommend Trypanocidal drugs for late-stage, symptomatic Chagas disease

17 Jan, 2021 | 21:44h | UTC

Trypanocidal drugs for late‐stage, symptomatic Chagas disease (Trypanosoma cruzi infection) – Cochrane Library

Summary: Trypanocidal drugs for late-stage, symptomatic Chagas disease – Cochrane Library

 

Observational study: Among patients hospitalized with Covid-19 not receiving mechanical ventilation, transfusion of plasma with higher anti–SARS-CoV-2 IgG antibody levels is linked to lower risk of death than transfusion of plasma with lower antibody levels

15 Jan, 2021 | 08:59h | UTC

Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19 – New England Journal of Medicine

Editorial: (A Little) Clarity on Convalescent Plasma for Covid-19 – New England Journal of Medicine

Commentaries: Expert reaction to study looking at convalescent plasma antibody levels and risk of death from COVID-19 – Science Media Centre AND Antibody-rich convalescent plasma may lower risk of COVID death – CIDRAP

 

Opinion: RCTs don’t justify using convalescent plasma or antibody cocktails

15 Jan, 2021 | 08:58h | UTC

RCTs don’t justify using convalescent plasma or antibody cocktails – PulmCrit

 

[Preprint] Past COVID-19 infection provides some immunity but people may still carry and transmit virus

15 Jan, 2021 | 09:02h | UTC

Past COVID-19 infection provides some immunity but people may still carry and transmit virus – Public Health England

See also: Covid-19: Past infection provides 83% protection for five months but may not stop transmission, study finds – The BMJ AND COVID reinfections are unusual — but could still help the virus to spread – Nature AND COVID-19 infection gives some immunity, but virus can still be spread, study finds – Reuters AND Expert reaction to a preprint from the SIREN study looking at SARS-CoV-2 infection rates in antibody positive healthcare workers – Science Media Centre

 

Perspective: Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux?

15 Jan, 2021 | 08:51h | UTC

Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux? – HIV and ID Observations

Related video: Ivermectin For COVID-19 | A Doctor Explains – ZDoggMD

 

NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19”

15 Jan, 2021 | 08:53h | UTC

The COVID-19 Treatment Guidelines Panel’s Statement on the Use of Ivermectin for the Treatment of COVID-19 – National Institutes of Health

 

Covid-19 Vaccine — Frequently Asked Questions

15 Jan, 2021 | 08:49h | UTC

Covid-19 Vaccine — Frequently Asked Questions – New England Journal of Medicine

 

COVID-19 measures also suppress flu—for now

15 Jan, 2021 | 08:46h | UTC

COVID-19 measures also suppress flu—for now – Science

 

Covid-19 deaths are the highest they’ve ever been — and the more infectious variants could make things much worse

15 Jan, 2021 | 08:45h | UTC

Covid-19 deaths are the highest they’ve ever been — and the more infectious variants could make things much worse – STAT

 

Clinical trial finds vitamin D does not ward off colds and flu

15 Jan, 2021 | 08:33h | UTC

Clinical trial finds vitamin D does not ward off colds and flu – QIMR Berghofer Medical Research Institute

Original study: The effect of vitamin D supplementation on acute respiratory tract infection in older Australian adults: an analysis of data from the D-Health Trial – The Lancet Diabetes & Endocrinology

 

Cohort study: Piperacillin/tazobactam linked to increased risk of acute kidney injury when compared to cefepime or meropenem

15 Jan, 2021 | 08:24h | UTC

Risk of acute kidney injury and Clostridioides difficile infection with piperacillin/tazobactam, cefepime and meropenem with or without vancomycin – Clinical Infectious Diseases

 

Commentary on Twitter

 

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