Infectious Diseases (all articles)
[Press Release – Not Published Yet] Colchicine reduces the risk of COVID-19-related complications: Positive results from COLCORONA trial show that colchicine is the only effective oral medication for treating non-hospitalized patients
25 Jan, 2021 | 01:43h | UTCStudy Protocol: Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) (COVID-19) – ClinicalTrials.gov
“Patients will receive study medication colchicine 0.5 mg per os (PO) twice daily for the first 3 days and then once daily for the last 27 days.”
Commentaries: ‘Major breakthrough’ | Large study shows effectiveness of colchicine to treat COVID-19 – The Canadian AND A gout drug shows promise for Covid-19, but skeptics worry about trusting science by press release – STAT
Commentary on Twitter
Press release 🔥 #colchicine decreased ⬇️
🏥 hospitalizations 25%
🤕 use of ventilation 50%
💀 mortality 44%
in multinational trial of >4,000 non-hospitalized #COVID patientsMore: https://t.co/htMRdParq3
Full report awaited…@EricTopol @DrEricDing @MartinLandray #EBM pic.twitter.com/iodiEJBtV1
— Kari Tikkinen (@KariTikkinen) January 23, 2021
[Press Release – Not Published Yet] Full-dose blood thinners decreased need for life support and improved outcome in hospitalized COVID-19 patients
25 Jan, 2021 | 01:42h | UTC
Randomized trial: Bamlanivimab associated with Etesevimab reduce the viral load in patients with mild to moderate COVID-19
25 Jan, 2021 | 01:36h | UTCEditorial: Neutralizing Monoclonal Antibody for Mild to Moderate COVID-19
Randomized trial: Anakinra (IL-1 receptor antagonist) does not improve outcomes in patients with mild-to-moderate COVID-19
25 Jan, 2021 | 01:37h | UTCCommentary: The right place for IL-1 inhibition in COVID-19 – The Lancet Respiratory Medicine
Commentary on Twitter
NEW Research—Anakinra did not improve outcomes in patients with mild-to-moderate #COVID19 pneumonia
CORIMUNO-ANA-1 trial from Xavier Mariette & colleagueshttps://t.co/SU1Cqmk9MJ pic.twitter.com/gLUkKpKinl
— The Lancet Respiratory Medicine (@LancetRespirMed) January 23, 2021
Revisiting the UK’s strategy for delaying the second dose of the Pfizer covid-19 vaccine
25 Jan, 2021 | 01:32h | UTC
Commentary on Twitter
These new data suggest that the UK govt should reconsider the decision to delay the second dose of the Pfizer/BioNTech vaccine. If they are determined to continue with the delayed second dose, then a robust randomized evaluation is urgently required https://t.co/4xrBFwZWkN
— The BMJ (@bmj_latest) January 24, 2021
Systematic review: At least one third of SARS-CoV-2 infections are asymptomatic
25 Jan, 2021 | 01:33h | UTCCommentary from the authors: The day we let Covid-19 spin out of control – STAT
CDC Report: Allergic reactions including anaphylaxis after receipt of the first dose of Moderna COVID-19 vaccine
25 Jan, 2021 | 01:29h | UTCCommentary: CDC reports rare allergic reactions to Moderna’s Covid-19 vaccine – STAT
Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline
25 Jan, 2021 | 01:35h | UTCOriginal Guideline: COVID-19 rapid guideline: managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence
Covid-19: Reports from Israel suggest one dose of Pfizer vaccine could be less effective than expected
25 Jan, 2021 | 01:30h | UTC
Randomized trial: No benefit from corticosteroid nasal spray for recovery of smell sensation in COVID-19 patients
25 Jan, 2021 | 01:28h | UTC
Systematic Review: Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation
25 Jan, 2021 | 01:05h | UTC
5 Important Things To Know About Extended Spectrum Beta-Lactamases (ESBL): Insights From A Clinical Microbiologist
25 Jan, 2021 | 00:58h | UTC
[News release – Not published yet] Lilly’s neutralizing antibody prevented COVID-19 at nursing homes, reducing risk by up to 80 percent for residents
22 Jan, 2021 | 08:40h | UTCCommentaries: Eli Lilly says its monoclonal antibody prevented Covid-19 infections in clinical trial – STAT AND Expert reaction to press release from Lilly about their neutralising antibody bamlanivimab and results from the BLAZE-2 trial looking at prevention of COVID-19 in nursing homes in the US – Science Media Centre
Airborne transmission of SARS-CoV-2: What we know
22 Jan, 2021 | 08:38h | UTCAirborne Transmission of SARS-CoV-2: What We Know – Clinical Infectious Diseases
Commentary on Twitter
Our workshop summary on airborne transmission of SARS-CoV-2 is out. Thanks to all the leading scientists who helped lead this amazing and impactful workshop! @theNASEM @linseymarr @kprather88 @Lakdawala_Lab https://t.co/MKfNA0QatN
— John Volckens (@Smogdr) January 18, 2021
Clinical update: Allergic reactions including anaphylaxis after receipt of the first dose of Pfizer-BioNTech COVID-19 vaccine
22 Jan, 2021 | 08:35h | UTCAuthor interview: COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions
Large cohort study identifies the most common hospital complications associated with COVID-19
22 Jan, 2021 | 08:36h | UTCCommentaries: Analysis of patient data reveals most common complications of COVID-19 – Medical News Today AND Study confirms most common complications associated with COVID-19 – New Medical
Commentary on Twitter
Large study of patients in the US who contracted #COVID19 confirms complications. Most common: pneumonia, respiratory failure, kidney failure, and sepsis or systemic inflammation. Read the research: https://t.co/GUUO1pgU9E @FralickMike pic.twitter.com/ZeMWEl3fi7
— CMAJ (@CMAJ) December 8, 2020
Perspective: Vaccinating children against Covid-19 — the lessons of measles
22 Jan, 2021 | 08:34h | UTCVaccinating Children against Covid-19 — The Lessons of Measles – New England Journal of Medicine
Patients, clinicians seek answers to the mystery of ‘Long COVID’
22 Jan, 2021 | 08:32h | UTCPatients, clinicians seek answers to the mystery of ‘Long COVID’ – CIDRAP
Twenty articles that critical care clinicians should read about COVID-19
22 Jan, 2021 | 08:28h | UTCTwenty articles that critical care clinicians should read about COVID-19 – Intensive Care Medicine
Commentary on Twitter
Main early papers on #COVID19 & their findings, an overview:
➡️ manifestations of severe disease
➡️ pharmacological therapy
➡️ ventilatory support in pts with #SARSCoV2 related #ARDS
➡️ healthcare organization & healthcare worker stress#FOAMcc #COVIDFOAM https://t.co/PvwsKhHn9v pic.twitter.com/QVg4zXU5TT— Intensive Care Medicine (@yourICM) January 4, 2021
Previous dengue infection and mortality in COVID-19
22 Jan, 2021 | 08:30h | UTCPrevious dengue infection and mortality in COVID-19 – Clinical Infectious Diseases
Commentary on Twitter
Study of 2,351 people with #COVID19 from Brazil, of whom 50% had previously been infected with dengue. Past dengue infection was associated with a halving in the risk of death from COVID-19, suggesting dengue might provide some immunity against SARS-CoV-2.https://t.co/EgD1U43WVL pic.twitter.com/RQlnOdS2Px
— Dr Zoë Hyde (@DrZoeHyde) January 3, 2021
Meta-analysis of randomized trials: Closed incision negative pressure wound therapy decreases surgical site infections compared to standard dressings after revision total joint arthroplasty, but not primary total joint arthroplasty
22 Jan, 2021 | 08:02h | UTCClosed Incision Negative Pressure Wound Therapy for Elective Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Journal of Arthroplasty (link to abstract – $ for full-text)
‘A bloody mess’: Confusion reigns over naming of new COVID variants
21 Jan, 2021 | 01:27h | UTC‘A bloody mess’: Confusion reigns over naming of new COVID variants – Nature
[Preprint] South African COVID-19 variant escapes neutralization by antibodies in COVID-19 convalescent plasma
21 Jan, 2021 | 01:28h | UTCSARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma – bioRxiv
Commentaries: Expert reaction to preprint reporting that the South African SARS-CoV-2 variant 501Y.V2 escapes neutralisation by COVID-19 donor plasma – Science Media Centre AND S.Africa virus strain poses ‘re-infection risk’: study – MedicalXpress
5 reasons to wear a mask even after you’re vaccinated
21 Jan, 2021 | 01:24h | UTC5 Reasons to Wear a Mask Even After You’re Vaccinated – Kaiser Health News
COVID’s toll on smell and taste: what scientists do and don’t know
21 Jan, 2021 | 01:26h | UTCCOVID’s toll on smell and taste: what scientists do and don’t know – Nature