Infectious Diseases (all articles)
RCT: Delayed antibiotic prescription feasible for children with uncomplicated respiratory infections
12 Feb, 2021 | 02:02h | UTCDelayed Antibiotic Prescription for Children With Respiratory Infections: A Randomized Trial – Pediatrics (link to abstract – $ for full-text)
Commentary: Data support delayed antibiotics in kids with respiratory infections – CIDRAP
Cohort study: The use of macrolide antibiotics in pregnancy is not associated with an increased risk of major congenital malformations
12 Feb, 2021 | 02:04h | UTC
RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19
12 Feb, 2021 | 02:25h | UTCNews release: Tocilizumab reduces deaths in patients hospitalised with COVID-19 – University of Oxford
Commentary: Tocilizumab cuts death rate in severe COVID-19, study finds – CIDRAP
Commentary on Twitter
👇RECOVERY pre-print:
Tocilizumab
– reduces mortality
– shortens hospital stay
– reduces progression to invasive mechanical ventilationClear benefits on top of corticosteroids
Good news!https://t.co/dal17tQG5b
— Martin Landray (@MartinLandray) February 11, 2021
Study: New B.1.1.7 variant does not result in more severe disease in children compared to the original strain
12 Feb, 2021 | 02:23h | UTC
Commentary on Twitter
There were recent concerns and media reports that B.1.1.7 has more effects in children and young adults than the ancestral strain. Here are new data to provide reassurance that's not the case @LancetChildAdol https://t.co/85Dj4tl2qq pic.twitter.com/YmNOeOhpTB
— Eric Topol (@EricTopol) February 11, 2021
Podcast: Does vaccination mean the end of masking and social distancing?
12 Feb, 2021 | 02:22h | UTCDoes Vaccination Mean the End of Masking and Social Distancing? – New England Journal of Medicine
Fully vaccinated people can skip Covid quarantines, CDC says
12 Feb, 2021 | 02:21h | UTCFully vaccinated people can skip Covid quarantines, CDC says – CNN
Video (6 min): A visual guide to the new coronavirus variants
12 Feb, 2021 | 02:20h | UTCA Visual Guide to the New Coronavirus Variants – Scientific American
Opinion: It’s time to consider vaccine mandates in high-risk settings
12 Feb, 2021 | 02:19h | UTCIt’s Time to Consider Vaccine Mandates in High-Risk Settings – Scientific American
Commentary on Twitter
It's Time to Consider #Vaccine Mandates in High-Risk Settings
"Leaving vaccination to individual choice is unacceptably high in places like #NursingHomes, #LongTermCare facilities and #Prisons"
Professors @doritmi @ArthurCaplan in @sciam https://t.co/km2PZPM5bK
— Paul Belcher *ON BLUESKY – DORMANT ON X* (@PaulJBelcher) January 28, 2021
[Preprint] Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
12 Feb, 2021 | 02:14h | UTCSix-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19 – medRxiv
Commentary: Covid linked to risk of mental illness and brain disorder, study suggests – The Guardian
Perspective: Mandating COVID-19 Vaccines—Ethical and Legal Considerations
12 Feb, 2021 | 02:18h | UTCMandating COVID-19 Vaccines – JAMA
Commentary on Twitter
Mandatory #COVID #vaccines are of intense interest. Now, in @JAMA_current, Dan Salmon @JohnsHopkinsSPH, @ProfHeidiLarson & I examine whether it's lawful & ethical. We cover mandates ordered by states, employers, schools, unis & as a condition of service. https://t.co/n9MQN3p1Wi pic.twitter.com/GmacRB5KKZ
— Lawrence Gostin (@LawrenceGostin) December 29, 2020
SR: How accurate are tests (Xpert Ultra and Xpert MTB/RIF) for diagnosing extrapulmonary tuberculosis and rifampicin resistance?
12 Feb, 2021 | 01:55h | UTC
Commentary on Twitter
How accurate are tests for diagnosing #tuberculosis #TB outside the lungs and rifampicin resistance? This @Cochrane_IDG systematic review found that Xpert Ultra and Xpert MTB/RIF may be helpful in diagnosing extrapulmonary tuberculosis. https://t.co/H79gK5CcR0 pic.twitter.com/bVy88zNpqQ
— The Cochrane Library (@CochraneLibrary) February 5, 2021
Combination of vancomycin plus piperacillin and risk of acute kidney injury: a worldwide pharmacovigilance database analysis
11 Feb, 2021 | 01:50h | UTCRelated: Risk of acute kidney injury and Clostridioides difficile infection with piperacillin/tazobactam, cefepime and meropenem with or without vancomycin – Clinical Infectious Diseases AND Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text) AND Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children – JAMA Pediatrics (link to abstract – $ for full-text) AND Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients – Critical Care
Commentary on Twitter
🚨 New paper from our team @HopitalCochin ⤵️
New data supporting a drug-drug interaction between vancomycin and piperacillin ⚠️ increased risk of acute kidney injury | Great collab with @AdrienContejean
@KerneisSolen
Read more in @BSACandJAC ⤵️https://t.co/eQW5s52fOY@ABsteward— Laurent Chouchana (@LChouchana) February 1, 2021
RCT: Among patients undergoing transurethral resection of the prostate, it is safe to withhold antimicrobial prophylaxis for those without pre-operative pyuria or a pre-operative, indwelling catheter
11 Feb, 2021 | 01:52h | UTC
CDC Analysis: Effectiveness of mask wearing to control community spread of SARS-CoV-2
11 Feb, 2021 | 02:22h | UTCEffectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2 – JAMA
Author interview: Mask Wearing for COVID-19 Prevention—Summary of CDC Data
With emergence of more transmissible #SARSCoV2 variants it is even more important to adopt widespread mask wearing and to redouble use of other nonpharmaceutical prevention measures until effective levels of vaccination are achieved nationally https://t.co/TSuh8Vjc29 @CDCgov
— JAMA (@JAMA_current) February 10, 2021
CDC Guidance: Improve the fit and filtration of your mask to reduce the spread of COVID-19
11 Feb, 2021 | 02:21h | UTC
CDC study on practical ways for maximizing fit for masks to reduce SARS-CoV-2 transmission and exposure
11 Feb, 2021 | 02:25h | UTCCommentaries: CDC Says Double-Masking Offers More Protection Against The Coronavirus – NPR AND CDC report: Double-masking can block more than 90 percent of viral particles – NBC News
Case report: Severe reinfection with South African SARS-CoV-2 variant
11 Feb, 2021 | 02:17h | UTC
Commentary on Twitter
🔥NEW Case report 🔥#CID @IDSAInfo
Severe reinfection with South African SARS-CoV-2 501Y.V2 lineage B.1.351 variant four months after a first mild infection. @InfectiousDz https://t.co/zjjJED4r0D— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 10, 2021
Small RCT: Inhaled budesonide reduces the need for hospitalization in COVID-19 patients
11 Feb, 2021 | 02:18h | UTCCommentaries: Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests – University of Oxford AND Expert reaction to preprint on an RCT of inhaled budesonide in the treatment of early COVID-19 – Science Media Centre
WHO experts recommend AstraZeneca COVID vaccine across all ages and countries
11 Feb, 2021 | 02:20h | UTCCommentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR
ACP: Update on Remdesivir use for hospitalized COVID-19 patients
11 Feb, 2021 | 02:15h | UTC
Perspective: Leave your antibodies alone
11 Feb, 2021 | 02:12h | UTCLeave Your Antibodies Alone – The Atlantic
Researchers investigate What COVID-19 does to the heart
11 Feb, 2021 | 02:14h | UTCResearchers Investigate What COVID-19 Does to the Heart – JAMA
Definitely not the flu: risk of death from COVID-19 3.5 times higher than from flu
11 Feb, 2021 | 02:11h | UTCNews release: Definitely not the flu: risk of death from COVID-19 3.5 times higher than from flu
Original study: Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area – Canadian Medical Association Journal
Cohort study: Adjunctive clindamycin may benefit beta-lactam antibiotic-treated patients with invasive beta-hemolytic streptococcal infections
10 Feb, 2021 | 01:13h | UTCEffectiveness of adjunctive clindamycin in β-lactam antibiotic-treated patients with invasive β-haemolytic streptococcal infections in US hospitals: a retrospective multicentre cohort study – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
Our new study in Lancet ID 🔥🔥 showing a potential role for wider adjunctive use of clindamycin for iGAS even without next fasc or toxic shock. Utility in non-A,non-B strep questionable. Congratulations to stellar first author @Ahmed_HBabiker https://t.co/3t4FsmClWa
— Sameer Kadri (@SameerKadri12) December 15, 2020
COVAX statement on new variants of SARS-CoV-2
10 Feb, 2021 | 01:53h | UTCCOVAX Statement on New Variants of SARS-CoV-2 – World Health Organization