Covid-19
Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19
15 Feb, 2021 | 01:18h | UTCCommentaries: Preventive blood thinning drugs could reduce COVID hospital deaths – London School of Hygiene & Tropical Medicine AND Preventive blood thinning drugs linked to reduced risk of death in COVID-19 patients – The BMJ AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre AND
Commentary on Twitter
Blood thinning drugs are now linked to a reduced risk of death for COVID19 patients. Those given preventive blood thinners (prophylactic anticoagulants) within 24 hours of hospital admission for Covid were less likely to die. New report in the BMJ https://t.co/KQqQ3Zoj8B pic.twitter.com/6wJj8mEucw
— delthia ricks 🔬 (@DelthiaRicks) February 12, 2021
Take whatever COVID vaccine you can get. All of them stop death and hospitalization
15 Feb, 2021 | 01:17h | UTCTake whatever COVID vaccine you can get. All of them stop death and hospitalization – USA Today
“All seven COVID-19 vaccines that have completed large efficacy trials — Pfizer, Moderna, Johnson & Johnson, Novavax, AstraZeneca, Sputnik V and Sinovac — appear to be 100% effective for serious complications. Not one vaccinated person has gotten sick enough to require hospitalization. Not a single vaccinated person has died of COVID-19.”
Small RCT: No effect from Zinc and Vitamin C supplementation among ambulatory patients with SARS-CoV-2 infection
15 Feb, 2021 | 01:20h | UTCCommentaries: Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds – CNN AND Supplements for the Treatment of Mild COVID-19—Challenging Health Beliefs With Science From A to Z – JAMA Network Open AND Zinc, vitamin C show no effect for COVID-19 in small study – CIDRAP AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre
Commentary on Twitter
RCT finds high-dose zinc, ascorbic acid (vitamin C), or both, did not significantly decrease the duration of symptoms in ambulatory patients with #COVID19 vs standard of care. @DesaiMilindY @ClevelandClinic @ErinMichos @miguelcainzos23 #VisualAbstract https://t.co/ahcc2awJB8
— JAMA Network Open (@JAMANetworkOpen) February 12, 2021
Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment
15 Feb, 2021 | 01:14h | UTC
Commentaries on Twitter
NEW—#COVID19 vaccination potential will not be achieved without increased production, affordable pricing, global availability, & successful rollout. This Health Policy compares potential of 26 leading vaccines + vaccine confidence in 32 countries. Read https://t.co/QFeRDHutAi pic.twitter.com/rgknOgCVkg
— The Lancet (@TheLancet) February 12, 2021
The practical issues of #SARSCoV2 vaccines, a new and comprehensive review @TheLancet https://t.co/6sHsac44Ej best current summary of production, $, allocation, deployment, by @ojwouters @LSEHealthPolicy and colleagues pic.twitter.com/mMxOgkjyi0
— Eric Topol (@EricTopol) February 13, 2021
Limited transmission of COVID-19 from open schools but teachers were affected: Swedish study
15 Feb, 2021 | 01:11h | UTCOriginal Study: The effects of school closures on SARS-CoV-2 among parents and teachers – Proceedings of the National Academy of Sciences
Commentary on Twitter
New data open vs closed schools from Sweden, and particularly the risk of #SARSCoV2 infections and hospitalizations among teachers, while low, doubled in upper-secondary. Parents: 17% increasehttps://t.co/y1N02xwLfc @PNASNews by @jonasvlachos @helenasvaleryd @UU_University
— Eric Topol (@EricTopol) February 11, 2021
Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US
15 Feb, 2021 | 01:13h | UTCAuthor interview: COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions – JAMA
Commentary on Twitter
More than 17.5 million doses of Pfizer & Moderna vaccine were administered between Dec 14 – Jan 18, in USA.
Only 66 cases of anaphylaxis were reported & all but 1 case occurred within 11 min of vaccination.
0 deaths.https://t.co/P1YJISkHZE
— Isaac Bogoch (@BogochIsaac) February 12, 2021
CDC says it’s safe to reopen schools — with proper precautions
15 Feb, 2021 | 01:09h | UTCCDC says it’s safe to reopen schools — with proper precautions – Vox
See also: CDC Offers Clearest Guidance Yet For Reopening Schools – NPR
Guideline: Schools and Child Care Programs – Centers for Disease Control and Prevention
[Preprint] Covid-19 vaccination associated with reduced viral load, may reduce transmission
15 Feb, 2021 | 01:07h | UTCDecreased SARS-CoV-2 viral load following vaccination – medRxiv
Commentary: COVID-19 vaccination associated with 3- to 5-fold reduction in viral load – News Medical
Increase aerosol transmission of Covid-19 with increased age and obesity
15 Feb, 2021 | 01:03h | UTCCommentary: Older, heavier adults possible ‘superspreaders’ of COVID-19, study finds – UPI AND Researchers unravel what makes someone a COVID-19 super-spreader – Tulane University
France’s health authority recommends single vaccine shot for people who have had COVID-19
15 Feb, 2021 | 01:02h | UTCFrance’s health authority recommends single vaccine shot for people who have had COVID-19 – Euronews
See also: Covid: France says just one jab needed for previously infected – BBC
Related: Covid-19: People who have had infection might only need one dose of mRNA vaccine – The BMJ AND You’ve had COVID: maybe one dose of vaccine is enough, studies suggest – MedicalXpress
RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19
12 Feb, 2021 | 02:25h | UTCNews release: Tocilizumab reduces deaths in patients hospitalised with COVID-19 – University of Oxford
Commentary: Tocilizumab cuts death rate in severe COVID-19, study finds – CIDRAP
Commentary on Twitter
👇RECOVERY pre-print:
Tocilizumab
– reduces mortality
– shortens hospital stay
– reduces progression to invasive mechanical ventilationClear benefits on top of corticosteroids
Good news!https://t.co/dal17tQG5b
— Martin Landray (@MartinLandray) February 11, 2021
Study: New B.1.1.7 variant does not result in more severe disease in children compared to the original strain
12 Feb, 2021 | 02:23h | UTC
Commentary on Twitter
There were recent concerns and media reports that B.1.1.7 has more effects in children and young adults than the ancestral strain. Here are new data to provide reassurance that's not the case @LancetChildAdol https://t.co/85Dj4tl2qq pic.twitter.com/YmNOeOhpTB
— Eric Topol (@EricTopol) February 11, 2021
Podcast: Does vaccination mean the end of masking and social distancing?
12 Feb, 2021 | 02:22h | UTCDoes Vaccination Mean the End of Masking and Social Distancing? – New England Journal of Medicine
Fully vaccinated people can skip Covid quarantines, CDC says
12 Feb, 2021 | 02:21h | UTCFully vaccinated people can skip Covid quarantines, CDC says – CNN
Video (6 min): A visual guide to the new coronavirus variants
12 Feb, 2021 | 02:20h | UTCA Visual Guide to the New Coronavirus Variants – Scientific American
Opinion: It’s time to consider vaccine mandates in high-risk settings
12 Feb, 2021 | 02:19h | UTCIt’s Time to Consider Vaccine Mandates in High-Risk Settings – Scientific American
Commentary on Twitter
It's Time to Consider #Vaccine Mandates in High-Risk Settings
"Leaving vaccination to individual choice is unacceptably high in places like #NursingHomes, #LongTermCare facilities and #Prisons"
Professors @doritmi @ArthurCaplan in @sciam https://t.co/km2PZPM5bK
— Paul Belcher *ON BLUESKY – DORMANT ON X* (@PaulJBelcher) January 28, 2021
[Preprint] Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
12 Feb, 2021 | 02:14h | UTCSix-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19 – medRxiv
Commentary: Covid linked to risk of mental illness and brain disorder, study suggests – The Guardian
Perspective: Mandating COVID-19 Vaccines—Ethical and Legal Considerations
12 Feb, 2021 | 02:18h | UTCMandating COVID-19 Vaccines – JAMA
Commentary on Twitter
Mandatory #COVID #vaccines are of intense interest. Now, in @JAMA_current, Dan Salmon @JohnsHopkinsSPH, @ProfHeidiLarson & I examine whether it's lawful & ethical. We cover mandates ordered by states, employers, schools, unis & as a condition of service. https://t.co/n9MQN3p1Wi pic.twitter.com/GmacRB5KKZ
— Lawrence Gostin (@LawrenceGostin) December 29, 2020
CDC Analysis: Effectiveness of mask wearing to control community spread of SARS-CoV-2
11 Feb, 2021 | 02:22h | UTCEffectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2 – JAMA
Author interview: Mask Wearing for COVID-19 Prevention—Summary of CDC Data
With emergence of more transmissible #SARSCoV2 variants it is even more important to adopt widespread mask wearing and to redouble use of other nonpharmaceutical prevention measures until effective levels of vaccination are achieved nationally https://t.co/TSuh8Vjc29 @CDCgov
— JAMA (@JAMA_current) February 10, 2021
CDC Guidance: Improve the fit and filtration of your mask to reduce the spread of COVID-19
11 Feb, 2021 | 02:21h | UTC
Case report: Severe reinfection with South African SARS-CoV-2 variant
11 Feb, 2021 | 02:17h | UTC
Commentary on Twitter
🔥NEW Case report 🔥#CID @IDSAInfo
Severe reinfection with South African SARS-CoV-2 501Y.V2 lineage B.1.351 variant four months after a first mild infection. @InfectiousDz https://t.co/zjjJED4r0D— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 10, 2021
Small RCT: Inhaled budesonide reduces the need for hospitalization in COVID-19 patients
11 Feb, 2021 | 02:18h | UTCCommentaries: Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests – University of Oxford AND Expert reaction to preprint on an RCT of inhaled budesonide in the treatment of early COVID-19 – Science Media Centre
WHO experts recommend AstraZeneca COVID vaccine across all ages and countries
11 Feb, 2021 | 02:20h | UTCCommentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR
ACP: Update on Remdesivir use for hospitalized COVID-19 patients
11 Feb, 2021 | 02:15h | UTC
Perspective: Leave your antibodies alone
11 Feb, 2021 | 02:12h | UTCLeave Your Antibodies Alone – The Atlantic


