Covid-19
Perspective | Don’t Be Surprised When Vaccinated People Get Infected
24 Mar, 2021 | 08:28h | UTCDon’t Be Surprised When Vaccinated People Get Infected – The Atlantic
Opinion | Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks
24 Mar, 2021 | 08:22h | UTC
Commentary on Twitter
Editor's Pick—How do different contact tracing & testing methods work? What resources are needed for each? How do features of #COVID19 transmission influence their effectiveness?
Read the Personal View by @LeeKShaffer et al. in @LancetMicrobe. https://t.co/ruHV0RW6aY pic.twitter.com/19f7vCrt0I
— The Lancet (@TheLancet) March 18, 2021
[Press release – not published yet] AstraZeneca vaccine 79% effective for preventing symptomatic COVID-19
23 Mar, 2021 | 02:36h | UTCCommentaries: AstraZeneca vaccine is 79% effective against symptomatic Covid-19, company says – CNN AND AstraZeneca’s Covid-19 vaccine shows better-than-expected efficacy in U.S. trial – STAT AND Expert reaction to press release from AstraZeneca announcing interim data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca Publishes Reassuring Trial Data, But Vaccine Hesitancy Remains Widespread In European Union – Health Policy Watch
Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery
23 Mar, 2021 | 02:33h | UTCSARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery – Anaesthesia
Commentary on Twitter
Our research has underpinned key recommendations in new guidance on SARS-CoV-2 infection & elective surgery from @Assoc_Anaes & @RCoANews & @RCSnews.
This guideline can act as a template for policy makers in other countries!
🆓https://t.co/kKgJXFf0vd pic.twitter.com/mJRasJTJws
— COVIDSurg (@CovidSurg) March 20, 2021
EMA advises against use of ivermectin for the prevention or treatment of COVID-19 outside randomized clinical trials
23 Mar, 2021 | 02:30h | UTCRelated: FDA: Why you should not use Ivermectin to treat or prevent COVID-19 (statement, commentary, and RCT)
Opinion | We need to start thinking more critically — and speaking more cautiously — about long Covid
23 Mar, 2021 | 02:28h | UTCWe need to start thinking more critically — and speaking more cautiously — about long Covid – STAT
Review | Post-acute COVID-19 syndrome
23 Mar, 2021 | 02:26h | UTCPost-acute COVID-19 syndrome – Nature Medicine
News Release: Study underscores need for multidisciplinary care for COVID-19 long-haulers – Dana-Farber Cancer Institute
Lung ultrasound for the early diagnosis of COVID-19 pneumonia: an international multicenter study
23 Mar, 2021 | 02:20h | UTC
Commentary on Twitter
Lung #ultrasound based approach for early diagnosis of #COVID19 pneumonia:
➡️20 US/European hospitals
➡️1462 pts
Combining #LUS patterns of probability + clinical characteristics allow to rapidly rule in/out #SARSCoV2 pneumonia at bedside w high accuracy!https://t.co/GqsOZoIdgc pic.twitter.com/eENciXi9Cf— Intensive Care Medicine (@yourICM) March 20, 2021
Editorial | Scholarly communications harmed by covid-19
23 Mar, 2021 | 02:25h | UTCScholarly communications harmed by covid-19 – The BMJ
Commentaries on Twitter
Our new editorial in @bmj_latest
The covid-19 pandemic has accentuated an erosion in civility in academic discourse, leading to deep divisions
Measured, constructive criticism confined to the content, *not the person*, is the basis of academic freedomhttps://t.co/8NVVVTDz5I
— Alasdair Munro (@apsmunro) March 22, 2021
The pandemic has accentuated an erosion in civility in academic discourse, leading to deep divisions being played out in the media. This is potentially harmful to public trust in scientists and healthcare professionals, say Raj Bhopal and @apsmunrohttps://t.co/31bQm2GJfD
— The BMJ (@bmj_latest) March 22, 2021
Covid-19 disruptions killed 228,000 children in South Asia, says UN report
23 Mar, 2021 | 02:22h | UTCCovid-19 disruptions killed 228,000 children in South Asia, says UN report – BBC
Report: Direct and indirect effects of the COVID-19 pandemic and response in South Asia – United Nations
Opinion | An open plea for dignity and respect in science
23 Mar, 2021 | 02:24h | UTCAn open plea for dignity and respect in science – The BMJ Opinion
Related: Scientists who express different views on Covid-19 should be heard, not demonized – STAT
Commentary on Twitter
Only by listening to and debating honest opposing views, can we hope to overcome the fear and anger that surrounds us. #COVID19 #pandemia
With @iona_heath and Jerome Hoffman @bmj_latest Opinion blog.https://t.co/deGGapwhnS pic.twitter.com/BtUkfhUIV0
— Luca De Fiore (@lucadf) March 22, 2021
Expert consensus statements for the management of COVID-19-related acute respiratory failure
21 Mar, 2021 | 22:05h | UTC
Commentary on Twitter
👌Expert consensus statements for the management of 👍💥 COVID-19-related acute respiratory failure using a Delphi method.
👇👇👇👇👇https://t.co/ujt8669VAb pic.twitter.com/AlT0ZkdKSc— RECAT👩🏽⚕️🏥👨🏽⚕️🇲🇽🫀 (@LeslieMegom) March 17, 2021
Infection and mRNA vaccine-induced immunity may be retained against SARS-CoV-2 variant B.1.1.7
21 Mar, 2021 | 22:04h | UTCNeutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination – JAMA
SARS-CoV-2 variants B.1.351 and P.1 can escape from therapeutic antibodies and evade antibodies induced by infection or mRNA vaccination
21 Mar, 2021 | 22:02h | UTCSARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies – Cell
CDC Guidance for schools says students can now stay 3 feet apart, rather than 6
21 Mar, 2021 | 22:07h | UTCCommentaries: CDC Says Schools Can Now Space Students 3 Feet Apart, Rather Than 6 – NPR AND CDC updates COVID school guidance, OKs 3-feet distancing – CIDRAP
Related: Cohort study: Effectiveness of three vs. six feet of physical distancing for controlling spread of COVID-19 among primary and secondary students and staff (study and commentary)
Commentaries on Twitter
CDC: Children in elementary schools don't need to be kept 6-feet apart. In a major policy revision, federal health officials said only 3 feet of distance is required between young children in classrooms https://t.co/UBvES1T6ps
— delthia ricks 🔬 (@DelthiaRicks) March 19, 2021
Very happy CDC now recommending 3 feet spacing in schools: "The change is momentous .because many schools.. operate on part-time or hybrid schedules in order to reduce class sizes. A 3-foot rule would allow many more schools to open in person, full time."https://t.co/wR88jdUBgM
— Monica Gandhi MD, MPH (@MonicaGandhi9) March 19, 2021
[Preprint] Oxford/AstraZeneca and Pfizer/BioNTech vaccines probably can still neutralize P.1 strain of SARS-CoV-2, but at lower levels
21 Mar, 2021 | 21:55h | UTCAntibody evasion by the Brazilian P.1 strain of SARS-CoV-2 – bioRxiv
Commentary: Existing COVID vaccines may protect against Brazilian variant – Oxford study – Reuters
B.1.351 strain of SARS-CoV-2 neutralization titer reduced 8- to 9-fold for Pfizer and AstraZeneca vaccinees. Convalescent plasma and therapeutic antibodies were less effective against this variant as well.
21 Mar, 2021 | 21:52h | UTCEvidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera – Cell
Bioethics | “Europe’s Vaccine Ethics Call: Do No Harm and Let More Die?”
21 Mar, 2021 | 21:50h | UTCEurope’s Vaccine Ethics Call: Do No Harm and Let More Die? – The New York Times (free registration may be required)
Related opinion: Covid-19 vaccine adverse events: balancing monitoring with confidence in vaccines – The BMJ Opinion
See also: European Medicines Agency finds AstraZeneca vaccine is safe and benefits outweigh the risks (Statement and commentaries) AND Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine – World Health Organization AND Update on the safety of COVID-19 Vaccine AstraZeneca (statement and commentaries)
Commentary on Twitter
Many bioethicists have a problem with how Europe halted use of the AstraZeneca vaccine. Keeping the vaccine available would have allowed people “to consensually protect themselves from a big risk by taking a very small one.” https://t.co/qctELhfFGI
— NYT Health (@NYTHealth) March 20, 2021
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review
21 Mar, 2021 | 21:49h | UTC
Commentary on Twitter
@JACCJournals: We share a systematic summary of #anticcogulation,#antiplatelet, and #fibrinolysis #RCTs in #COVID19. Amazing work by @AzitaTalasaz and a stellar multidisciplinary team! Figs illustrate areas where we’ll have evidence, & the gaps. Link: https://t.co/t4ksxwjAze pic.twitter.com/0Th3OZBXOY
— Behnood Bikdeli (@bbikdeli) March 16, 2021
Modeling Study: Vaccination alone is unlikely to contain COVID-19 infections in UK
21 Mar, 2021 | 21:46h | UTCCommentaries: Risking further COVID-19 waves despite vaccination – The Lancet Infectious Diseases AND Vaccination alone is unlikely to contain COVID-19 infections in UK – The Lancet
Commentary on Twitter
Vaccination alone is unlikely to contain #COVID19 infections in UK, suggests modelling study in @TheLancetInfDis—gradual release of control measures, high vaccine uptake, and high efficacy vaccine essential to minimise future waves. https://t.co/zpbPsYVHS2 pic.twitter.com/v47v6ux4r6
— The Lancet (@TheLancet) March 19, 2021
Clinician Guide to COVID-19 diagnostics in children
21 Mar, 2021 | 21:48h | UTCClinician guide to COVID-19 diagnostics – ADC Education & Practice
RCT: Intermediate-dose enoxaparin (1 mg/kg/d) not better than standard-dose prophylactic anticoagulation in patients with Covid-19 admitted to the intensive care unit
19 Mar, 2021 | 08:42h | UTCEditorial: Finding the Optimal Thromboprophylaxis Dose in Patients With COVID-19 – JAMA
Commentary on Twitter
Intermediate-dose prophylactic enoxaparin (1 mg/kg/d) had no effect on a primary composite outcome of adjudicated venous or arterial thrombosis, ECMO, or 30-d mortality vs standard dose enoxaparin among ICU patients w #COVID19 https://t.co/L6UdB31J7V
— JAMA (@JAMA_current) March 18, 2021
European Medicines Agency finds AstraZeneca vaccine is safe and benefits outweigh the risks
19 Mar, 2021 | 08:37h | UTCCommentaries: Restoring confidence after the covid-19 Oxford/AstraZeneca vaccine pause will be an uphill battle – The BMJ Opinion AND European Medicines Agency: AstraZeneca Vaccine Safe – Benefits Outweigh Risks – Despite Possible Rare Events – Health Policy Watch AND Expert reaction to announcement from EMA on Oxford-AstraZeneca vaccine and blood clots – Science Media Centre AND European regulators say AstraZeneca vaccine safe, but can’t rule out rare events – CIDRAP AND AstraZeneca vaccine safe, but rare risk of blood clots not ruled out, EU regulator says – LiveScience AND European Medicines Agency Finds AstraZeneca Vaccine Safe And Effective – NPR
Current evidence for COVID-19 therapies: a systematic literature review
19 Mar, 2021 | 08:36h | UTC
SARS-CoV-2 transmission without symptoms
19 Mar, 2021 | 08:30h | UTCSARS-CoV-2 transmission without symptoms – Science (a few articles per month are free)