Covid-19
WHO chief – The world can bring the global COVID-19 pandemic under control in the coming months provided it distributes the necessary resources fairly
25 Apr, 2021 | 22:08h | UTCSee also: Opinion | I Run the W.H.O., and I Know That Rich Countries Must Make a Choice – The New York Times
Commentary on Twitter
We have all the tools to tame the #COVID19 pandemic everywhere in a matter of months. It comes down to a simple choice: to share or not to share. My piece on #VaccinEquity in the @nytimes. https://t.co/OIRAogZPwl
— Tedros Adhanom Ghebreyesus (@DrTedros) April 23, 2021
Recommendations to address patients fear of adverse effects and COVID-19 vaccine hesitancy
25 Apr, 2021 | 21:58h | UTC
WHO: COVID-19 continues to disrupt essential health services in 90% of countries
25 Apr, 2021 | 22:12h | UTC
Commentary on Twitter (thread – click for more)
Over one year into the #COVID19 pandemic, about 9⃣0⃣% of countries surveyed still report one or more disruptions to essential health services. Major efforts are required to restore and strengthen services in all countries.
👉 https://t.co/P34xPKY1Io pic.twitter.com/UYDQPX67Vw
— World Health Organization (WHO) (@WHO) April 23, 2021
U.S. lifts pause on use of J&J’s Covid-19 vaccine
25 Apr, 2021 | 21:57h | UTCU.S. lifts pause on use of J&J’s Covid-19 vaccine – STAT
See also: CDC, FDA lift pause on using J&J’s coronavirus vaccine, add safety warning – CNN AND ACIP opts to lift pause on Johnson & Johnson vaccine – CIDRAP
One million coronavirus sequences: popular genome site hits mega milestone
25 Apr, 2021 | 21:59h | UTCOne million coronavirus sequences: popular genome site hits mega milestone – Nature
Resurgence of SARS-CoV-2: detection by community viral surveillance
25 Apr, 2021 | 21:55h | UTCResurgence of SARS-CoV-2: detection by community viral surveillance – Science
Commentary on Twitter
A #SARSCoV2 surveillance program tested in England in 2020 successfully detected a resurgence of virus infection at low prevalence, @imperialcollege researchers say. Such programs can augment routine surveillance to inform public health interventions. https://t.co/veilAJ8YX4 pic.twitter.com/9YFQbvtqbw
— Science Magazine (@ScienceMagazine) April 23, 2021
Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized
23 Apr, 2021 | 08:48h | UTCHigh-dimensional characterization of post-acute sequalae of COVID-19 – Nature
Commentary on Twitter (thread – click for more)
Happy to share the latest paper from our team in @nature
A comprehensive characterization of post acute sequelae of COVID-19#longcovid #PASChttps://t.co/AGLnYCamWe@VAResearch @vahsrd @WUSTL @WUSTLpubhealth @WUSTLmed @WUSTLnews @VREFSTL @Biostayan @BCBowe
— Ziyad Al-Aly, MD (@zalaly) April 22, 2021
NIH Updates COVID-19 Treatment Guidelines – adds recommendations on colchicine, fluvoxamine, and monoclonal antibodies
23 Apr, 2021 | 08:46h | UTCNIH Coronavirus Disease 2019 (COVID-19)
Treatment Guidelines – National Institutes of Health
RCT: COVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir
23 Apr, 2021 | 08:42h | UTCCOVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir – CIDRAP
Commentary on Twitter (thread – Click for more)
1/ No benefit from Hydroxychloroquine or Lopinavir-Ritonavir on Hospitalization/Viral clearance for COVID-19 https://t.co/yhXxv26418 via @JAMANetworkOpen part of @JAMANetwork
— Priya Sampathkumar (@PSampathkumarMD) April 22, 2021
Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19
23 Apr, 2021 | 08:39h | UTC
Commentary on Twitter
A 💥🆕 case series highlights that adults 50 years or younger with asymptomatic COVID-19 infection diagnosed by positive SARS-CoV-2 serological test result may present with ischemic stroke during the convalescent phase of the infection
https://t.co/BVlo7Z1hgn @JAMANetworkOpen— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 22, 2021
Covid-19: More data on the increased risks to pregnant women and their newborn infants
23 Apr, 2021 | 08:44h | UTCEditorial: COVID-19 in Pregnant Women and Their Newborn Infants
Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN
Commentary on Twitter
18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz
— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021
RCT: Single-Dose Johnson & Johnson Vaccine has 85% efficacy against severe/critical Covid-19 and maintains efficacy against variant B.1.351
22 Apr, 2021 | 08:50h | UTC
Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons
22 Apr, 2021 | 08:49h | UTCAudio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine
Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News
Covid-19: What do we know about airborne transmission of SARS-CoV-2?
23 Apr, 2021 | 08:33h | UTCCovid-19: What do we know about airborne transmission of SARS-CoV-2? – The BMJ
Related: Ten scientific reasons in support of airborne transmission of SARS-CoV-2 AND Editorial: Covid-19 has redefined airborne transmission
COVID vaccines and kids: five questions as trials begin
23 Apr, 2021 | 08:37h | UTCCOVID vaccines and kids: five questions as trials begin – Nature
Related perspective: Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark
Vaccine Breakthrough Infections with SARS-CoV-2 Variants
22 Apr, 2021 | 08:47h | UTCVaccine Breakthrough Infections with SARS-CoV-2 Variants – New England Journal of Medicine
Commentary on Twitter
Mild #COVID19 symptoms developed in two fully vaccinated persons. Serum tests showed high titers of antibodies capable of neutralizing the wild-type strain of #SARSCoV2 first identified in Wuhan, China, but sequencing of the virus isolates revealed novel variants.
— NEJM (@NEJM) April 21, 2021
Opinion | Platform Trials — Beware the Noncomparable Control Group
22 Apr, 2021 | 08:44h | UTCPlatform Trials — Beware the Noncomparable Control Group – New England Journal of Medicine
A year in the COVID-19 vaccine scheme COVAX
22 Apr, 2021 | 08:43h | UTCA year in the COVID-19 vaccine scheme COVAX – Reuters
Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease
22 Apr, 2021 | 08:40h | UTC
Commentaries on Twitter
Early data from @RCHMelbourne show that, at 3-6 month follow-up, all 151 children with mild and asymptomatic #COVID19 had returned to their baseline health status and post-acute COVID-19 symptoms had resolved.
Letter from @Shidan_Tosif & colleagues: https://t.co/XXa0EPIgPY
— The Lancet Child & Adolescent Health (@LancetChildAdol) April 20, 2021
Given such little available data, this study from Australia on post-acute COVID-19 symptoms in children is very important
Findings are extremely reassuring
Post-acute symptoms were rare, and mild (cough 4%, fatigue 2%, cough and fatigue 1%)
Great news!https://t.co/TEJyES3Crx
— Alasdair Munro (@apsmunro) April 21, 2021
Great to see research looking at whether long Covid is a problem in children.
From this Melbourne cohort, enduring cough and fatigue are uncommon.
It hasn’t been clear to me whether borders will reopen before children are vaccinated so this is VIP https://t.co/iLXqwXJmOt
— Jin Russell (@DrJinRussell) April 21, 2021
Truly encouraging data on post-acute #COVID19 in children. Single-center in Australia. n=151.
8% post-acute symptoms – all symptomatic COVID-19.
Mild symptoms: cough 4%, fatigue 2%, both 1%. Duration: cough 3-8w; post-viral fatigue 6-8w. All solved in follow-up time 3-6 months. https://t.co/vKrEFZlw3C— Pablo Guisado Vasco (@PabloGVasco) April 21, 2021
Perspective | Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe.
22 Apr, 2021 | 08:38h | UTCDo Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark
Commentary on Twitter
Great article by @Sara_Talpos
key qs:
1 Does a kid need to be vaccinated for their sake?
2 Does a kid need to be vaccinated to protect adults who decline?
3. Does a kid need to be vaccinated to protect adults who were vax'd?— Vinay Prasad MD MPH (@VPrasadMDMPH) April 20, 2021
India’s massive COVID surge puzzles scientists
22 Apr, 2021 | 08:36h | UTCIndia’s massive COVID surge puzzles scientists – Nature
See also: ‘The system has collapsed’: India’s descent into Covid hell – The Guardian AND India’s COVID-19 surge intensifies – CIDRAP
ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
21 Apr, 2021 | 07:11h | UTCSee also: Diagnostic Flow Chart
Commentary on Twitter
The ISTH has released interim guidance on vaccine-induced immune thrombotic thrombocytopenia (#VITT) to inform the management of suspected thrombosis in subjects who have recently received the AstraZeneca or Johnson & Johnson vaccine. https://t.co/qqtQtpywaf pic.twitter.com/wNmjNNDs4z
— ISTH (@isth) April 20, 2021
How COVID hurt the fight against other dangerous diseases
22 Apr, 2021 | 08:35h | UTCHow COVID hurt the fight against other dangerous diseases – Nature
Related: World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis AND WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1
COVID-19 Vaccine Janssen: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets
21 Apr, 2021 | 07:07h | UTCCommentary: Johnson & Johnson vaccine: EU regulator says blood clot very rare side effect – BBC
Commentary on Twitter
https://twitter.com/hildabast/status/1384535676482297865
Vaccine-induced Immune Thrombotic Thrombocytopenia: Frequently Asked Questions
21 Apr, 2021 | 07:09h | UTC


