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Covid-19

Review: COVID-19-associated coagulopathy and antithrombotic agents – In non-critically ill hospitalized patients, therapeutic dose anticoagulation may improve clinical outcomes. In critically ill patients, this same treatment does not improve outcomes, and prophylactic dose anticoagulation is recommended

29 Apr, 2021 | 08:46h | UTC

COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year – The Lancet Haematology

Related: Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials AND RCT: Intermediate-dose enoxaparin (1 mg/kg/d) not better than standard-dose prophylactic anticoagulation in patients with Covid-19 admitted to the intensive care unit

 

Commentary on Twitter

 

India’s surge leads to further global COVID rise as role of variants probed

29 Apr, 2021 | 08:41h | UTC

India’s surge leads to further global COVID rise as role of variants probed – CIDRAP

See also: India Blames a Virus Variant as Its Covid-19 Crisis Deepens – The New York Times (free registration required) AND Why the COVID-19 Variants Spreading in India Are a Global Concern – TIME

 

Commentary on Twitter (thread – click for more)

 

Brazilian regulatory authorities decide not to approve the Gamaleya vaccine

29 Apr, 2021 | 08:38h | UTC

Brazil Rejects the Gamaleya Vaccine – Science Translational Medicine

See also: Russia’s Sputnik V developers reject Brazil’s criticisms – Reuters

 

CDC Study: Pfizer-BioNTech and Moderna vaccines reduce Covid-19 hospitalization risk by 64% after the first dose and 94% after the second dose among adults aged ≥65 years

29 Apr, 2021 | 08:42h | UTC

Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries: Pfizer/Moderna Vaccine Protection: 64% at First Dose, 94% at Second – HealthDay AND Pfizer and Moderna vaccines reduce Covid-19 hospitalization risk by 94% among older adults, CDC study says – CNN

 

Commentary on Twitter

 

Ethics Commission Position Statement: Admission criteria and management of critical care patients in a pandemic context – “Age cannot be used as the sole criterion for admission nor denial of access to ICU settings”

29 Apr, 2021 | 08:36h | UTC

Admission criteria and management of critical care patients in a pandemic context: position of the Ethics Commission of the French Intensive Care Society, update of April 2021 – Annals of Intensive Care

 

China May Become World’s Biggest Vaccine Supplier As India Defaults On Global Deliveries

29 Apr, 2021 | 08:39h | UTC

China May Become World’s Biggest Vaccine Supplier As India Defaults On Global Deliveries – Health Policy Watch

 

Review: Systemic and organ-specific immune-related manifestations of COVID-19 – over 70 different systemic and organ-specific immune-related disorders have been reported

28 Apr, 2021 | 08:42h | UTC

Systemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology

 

CDC says fully vaccinated Americans can go outside without masks – but masks still needed in crowds

28 Apr, 2021 | 08:44h | UTC

CDC Guidance: Choosing Safer Activities – Centers for Disease Control and Prevention

Commentaries: CDC: If You’re Vaccinated, You Don’t Need To Mask Outdoors (Unless You’re In A Crowd) – NPR AND CDC: Fully vaccinated Americans can go maskless outdoors – CIDRAP

 

Commentary on Twitter (thread – click for more)

 

Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile

28 Apr, 2021 | 08:41h | UTC

Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile – Science

 

Commentary on Twitter

 

Covid-19 in India: Cases, deaths and oxygen supply

28 Apr, 2021 | 08:40h | UTC

Covid-19 in India: Cases, deaths and oxygen supply – BBC

See also: In Covid’s grip, India gasps for air: ‘If there is an apocalypse, this has to be one’ – STAT

 

How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)

28 Apr, 2021 | 08:36h | UTC

How the UK found the first effective Covid-19 treatment — and saved a million lives – Vox

Related: Covid-19: The Inside Story of the RECOVERY Trial AND Covid: The London bus trip that saved maybe a million lives – BBC

 

Scientists say the rush to do Covid research led to a whole lot of waste

28 Apr, 2021 | 08:34h | UTC

Scientists Say The Rush To Do COVID Research Led To A Whole Lot Of Waste – NPR

Original Article: How COVID-19 has fundamentally changed clinical research in global health – The Lancet Global Health

Related: Data Show Panic and Disorganization Dominate the Study of Covid-19 Drugs (other commentaries on the subject)

See also: The Lancet Series: Clinical Trials in Global Health

 

Commentary on Twitter (thread – click for more)

 

Tracking the Evolution of a ‘Variant of Concern’ in Brazil – “P.1 may be 1.7 to 2.4 times more transmissible than earlier variants”

28 Apr, 2021 | 08:38h | UTC

Tracking the Evolution of a ‘Variant of Concern’ in Brazil – NIH Director’s Blog

Related: Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science

 

Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a more severe clinical course

28 Apr, 2021 | 08:32h | UTC

Overview of SARS-CoV-2 infection in adults living with HIV – The Lancet HIV

 

Commentary on Twitter

 

Immunization services begin slow recovery from COVID-19 disruptions, though millions of children remain at risk from deadly diseases – WHO, UNICEF, Gavi

27 Apr, 2021 | 08:41h | UTC

Immunization services begin slow recovery from COVID-19 disruptions, though millions of children remain at risk from deadly diseases – WHO, UNICEF, Gavi – World Health Organization

Related report: Disability considerations for COVID-19 vaccination: WHO and UNICEF policy brief, 19 April 2021 – World Health Organization

 

Commentary on Twitter

 

Why the World Should Worry About India – “The world’s largest vaccine producer is struggling to overcome its latest COVID-19 surge—and that’s everyone’s problem.”

27 Apr, 2021 | 08:33h | UTC

Why the World Should Worry About India – The Atlantic

See also: Covid-19: Countries rally to support India through “storm that has shaken the nation” – The BMJ AND As India breaks another global Covid-19 record and hospitals run out of oxygen, countries pledge assistance and aid – CNN AND India’s COVID-19 crisis prompts global response – CIDRAP

 

Study in nursing homes shows rapid antigen testing could be a useful tool to identify contagious people at risk for transmitting SARS-CoV-2

27 Apr, 2021 | 08:35h | UTC

Performance Evaluation of Serial SARS-CoV-2 Rapid Antigen Testing During a Nursing Home Outbreak – Annals of Internal Medicine

Editorial: Utility of Rapid Antigen Tests in Nursing Homes

 

Commentary on Twitter

 

M-A: Prophylaxis against Covid-19: 1 – no benefit from Hydroxychloroquine; 2 – as studies on ivermectin so far have been small, it remains very uncertain whether ivermectin reduces SARS-CoV-2 infection

27 Apr, 2021 | 08:44h | UTC

Prophylaxis against covid-19: living systematic review and network meta-analysis – The BMJ

 

The Utility of Chest CT imaging in suspected or diagnosed COVID-19 Patients – a review of literature

27 Apr, 2021 | 08:30h | UTC

The Utility of Chest CT imaging in suspected or diagnosed COVID-19 Patients – a review of literature – CHEST Journal

 

Opinion | Real-world data, not predictions, should drive decisions on Covid-19 and school opening

27 Apr, 2021 | 08:26h | UTC

Real-world data, not predictions, should drive decisions on Covid-19 and school opening – STAT

 

Commentary from the author on Twitter

 

Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19

27 Apr, 2021 | 08:29h | UTC

Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19 – American Journal of Physical Medicine & Rehabilitation

 

Covid-19: Infections fell by 65% after first dose of AstraZeneca or Pfizer vaccine, data show

25 Apr, 2021 | 22:06h | UTC

COVID-19 continues to disrupt essential health services in 90% of countries – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

Clinical review of 43 patients with COVID-19-associated Acute Transverse Myelitis and 3 patients with Acute Transverse Myelitis reported post-vaccination

27 Apr, 2021 | 08:32h | UTC

Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222) – Frontiers in Immunology

Commentary: Rare neurological condition linked to COVID-19 cases in 21 countries – Houston Methodist

 

SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients

25 Apr, 2021 | 22:01h | UTC

SARS-CoV-2 and Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group – Stroke

 

Commentary on Twitter

 

Opinion | The International Community Has One Job: Getting COVID-19 Under Control

25 Apr, 2021 | 22:09h | UTC

The International Community Has One Job: Getting COVID-19 Under Control – Center for Global Development

 

Commentary on Twitter

 

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