Covid-19
RCT: No difference in 30-day mortality with discontinuation vs. continuation of renin-angiotensin-system inhibitors in patients with COVID-19, but secondary and explorative analysis showed discontinuation of RAS-inhibition may lead to a faster and better recovery.
14 Jun, 2021 | 08:47h | UTCEditorial: RAS inhibition and COVID-19: more questions than answers?
Related randomized trials showing no benefit from discontinuation: Randomized trial: No benefit from discontinuing ACE Inhibitors and ARBs in patients admitted with COVID-19 AND Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19
Video | Evaluation and care of patients with persistent symptoms following acute SARS-CoV-2 infection.
14 Jun, 2021 | 08:45h | UTC
Perspective | More transmissible, wilier variant makes Covid-19 vaccinations even more crucial, experts say.
14 Jun, 2021 | 08:42h | UTCMore transmissible, wilier variant makes Covid-19 vaccinations even more crucial, experts say – STAT
9 Steps to End COVID-19 and Prevent the Next Pandemic: Essential Outcomes From the World Health Assembly.
14 Jun, 2021 | 08:39h | UTC
Covid: Is there a limit to how much worse variants can get?
14 Jun, 2021 | 08:43h | UTCCovid: Is there a limit to how much worse variants can get? – BBC
Perspective | Does vaccinating adults stop kids from spreading COVID too?
11 Jun, 2021 | 08:32h | UTCDoes vaccinating adults stop kids from spreading COVID too? – Nature
High COVID vaccine uptake may protect the unvaccinated.
11 Jun, 2021 | 08:34h | UTCHigh COVID vaccine uptake may protect the unvaccinated – CIDRAP
Original Study: Community-level evidence for SARS-CoV-2 vaccine protection of unvaccinated individuals – Nature Medicine
Commentaries on Twitter
Just published @NatureMedicine
Evidence that "vaccination not only protects individuals who have been vaccinated but also provides cross-protection to unvaccinated individuals in the community" as seen in kids benefiting from high % of adults vaxxedhttps://t.co/IPQo6WTFZX pic.twitter.com/jtfD93onnn— Eric Topol (@EricTopol) June 10, 2021
https://twitter.com/niklasf/status/1402950991268433923
US donation of 500 million Pfizer vaccines could help ‘turn tide’ as Africa runs out of doses, says WHO.
11 Jun, 2021 | 08:31h | UTC
Naturally acquired SARS-CoV-2 immunity persists for up to 11 months following infection.
11 Jun, 2021 | 08:24h | UTC
CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare.
11 Jun, 2021 | 08:28h | UTCSee also: CDC plans “emergency meeting” on rare heart inflammation following COVID-19 vaccines – CBC News
Related: Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.
Opinion | The Covid-19 Delta variant poses a threat to our return to ‘normal’.
11 Jun, 2021 | 08:23h | UTCThe Covid-19 Delta variant poses a threat to our return to ‘normal’ – CNN
Commentary on Twitter
https://twitter.com/HoltgraveHealth/status/1402948596476039171
Editorial: Embrace the WHO’s new naming system for coronavirus variants.
10 Jun, 2021 | 09:48h | UTCEmbrace the WHO’s new naming system for coronavirus variants – Nature
Opinion | Epidemiology, not geopolitics, should guide COVID-19 vaccine donations.
10 Jun, 2021 | 09:51h | UTCEpidemiology, not geopolitics, should guide COVID-19 vaccine donations – The Lancet
Commentary on Twitter (thread – click for more)
Maximizing potential benefit of vaccine donations depends on doses going where they can do the"most good" but there's no consensus on where that would be
Murray @IHME_UW @RCReinerJr & I propose an approach that prioritizes epidemiology over geopolitics 1/https://t.co/OxOXLr5L55
— Tom Bollyky (@TomBollyky) June 9, 2021
Case series: Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia.
10 Jun, 2021 | 09:46h | UTC
Perspective | The four most urgent questions about long COVID.
10 Jun, 2021 | 09:47h | UTCThe four most urgent questions about long COVID – Nature
Perspective | Identifying and tracking SARS-CoV-2 variants — a challenge and an opportunity.
10 Jun, 2021 | 09:43h | UTC
COVID nails: these changes to your fingernails may show you’ve had coronavirus.
10 Jun, 2021 | 09:42h | UTCCOVID nails: these changes to your fingernails may show you’ve had coronavirus – The Conversation
Perspective | Uncertain effects of the pandemic on respiratory viruses.
10 Jun, 2021 | 09:41h | UTCUncertain effects of the pandemic on respiratory viruses – Science
Commentary on Twitter
A new #SciencePerspective argues that expanded genomic and clinical surveillance is needed to best understand the spread of respiratory viruses in a post-#COVID19 world.
🔎 Learn more: https://t.co/1rw3q76PZc pic.twitter.com/eyb4LDrfG7
— Science Magazine (@ScienceMagazine) June 9, 2021
[Preprint] RECOVERY trial finds aspirin does not improve survival for patients hospitalized with COVID-19.
9 Jun, 2021 | 08:28h | UTCNews Release: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19 – University of Oxford
Original Study: Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv
Commentary on Twitter (thread – click for more)
RECOVERY Pre-print: Aspirin
14,892 patients randomised to aspirin vs. usual care
– no impact on all-cause mortality (17% vs. 17%)
– similar results in all pre-specified subgroupshttps://t.co/ay5Xg4GBVD pic.twitter.com/aNJ09RTTOa— Martin Landray (@MartinLandray) June 8, 2021
COVID-19 Imaging: What we know now and what remains unknown.
9 Jun, 2021 | 08:27h | UTCCOVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology
Perspective | How COVID changed science.
9 Jun, 2021 | 08:24h | UTCHow COVID Changed Science – Scientific American
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
9 Jun, 2021 | 08:22h | UTC
China to offer COVID-19 vaccine to children as young as three.
9 Jun, 2021 | 08:26h | UTCChina to offer COVID-19 vaccine to children as young as three – MedicalXpress
See also: Sinovac says its vaccine is safe for children as young as 3 – Associated Press
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Short review: Neurological complications of COVID-19.
8 Jun, 2021 | 09:36h | UTCNeurological complications of COVID-19 – Intensive Care Medicine
Commentary on Twitter
NeuroCOVID potential mechanism(s)?
🧠 #COVID19 neuro-complications
🧠 direct neuroinvasion
🧠 inflammatory/autoimmune
🧠 vascular
+
🧠 #ICU complications
🧠 drugs toxicity/side effects
🧠 PICS/PACS & PTSD
Challenging to identify/diagnose: strictly monitor! https://t.co/0YlAoanUFo pic.twitter.com/unM0SWFR7L— Intensive Care Medicine (@yourICM) June 7, 2021