Covid-19
Perspective | We’re Asking the Impossible of Vaccines – “Complete protection against infection has long been hailed as the holy grail of vaccination. It might simply be unachievable”.
12 Sep, 2021 | 21:59h | UTCWe’re Asking the Impossible of Vaccines – The Atlantic
Commentary on Twitter
A really great read from @KatherineJWu on why it may be too much to expect vaccines—#covid19 or otherwise—to prevent infection. Still the vaccines are great at what we need—preventing hospitalizations and deaths! https://t.co/ufVBVn4wd1
— Jennifer Nuzzo, DrPH (@JenniferNuzzo) September 11, 2021
Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions.
12 Sep, 2021 | 22:03h | UTCRisk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions – CNN
Original study: Hospitalisation among vaccine breakthrough COVID-19 infections – The Lancet Infectious Diseases
News release: Study examines severe breakthrough cases of COVID-19 – YaleNews
Commentary on Twitter
New Comment: Hospitalisation among vaccine breakthrough #COVID19 infections https://t.co/1MtOoO8HVV, by Prerak V Juthani, @hyungjchun, and colleagues pic.twitter.com/mYAAEzHLDL
— The Lancet Infectious Diseases (@TheLancetInfDis) September 8, 2021
Perspective | How Endemic COVID Becomes a Manageable Risk – “Businesses and schools must adapt, because the dual threat from the coronavirus and the flu will be too severe”.
12 Sep, 2021 | 21:58h | UTCHow Endemic COVID Becomes a Manageable Risk – The Atlantic
Commentary on Twitter
.@TheAtlantic /@ScottGottliebMD — How Endemic COVID Becomes a Manageable Risk/We’re not going to annihilate COVID. Instead, our goal must be to weaken its punch so that it becomes a risk we can adapt to. https://t.co/TEX5kxBMO2
— Greg Folkers 🇺🇦☮️🇺🇸 (@greg_folkers) September 12, 2021
Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.
12 Sep, 2021 | 21:54h | UTCCommentary: Outcome Good at One Year for Majority of PIMS-TS Patients – HealthDay
Commentary on Twitter
A new study reports that a small number of pediatric patients are at risk for poor long-term outcomes of multisystem inflammatory syndrome in children. https://t.co/rUk4YEGRin pic.twitter.com/CgBi33Mzd5
— JAMA Pediatrics (@JAMAPediatrics) September 2, 2021
The Delta Covid variant and children: transmission in kids is low and only 2% hospitalized, report finds.
12 Sep, 2021 | 21:56h | UTCNews release: COVID-19 Delta variant in schools and early childhood education and care services in NSW, Australia: 16 June to 31 July 2021
Commentary on Twitter (thread – click for more)
Amazing education settings outbreak data from the Delta #COVID19 outbreak in NSW 🇦🇺
Primary/Secondary schools mostly closed, so limited info to draw on (Attack rate v low, <2%)
BUT early years settings fully open with no masks!
What happened? 🧵https://t.co/mG05e5Mp3T
1/
— Alasdair Munro (@apsmunro) September 8, 2021
RCT: Convalescent plasma does not improve outcomes and may be harmful to hospitalized patients with COVID-19.
10 Sep, 2021 | 05:37h | UTCNews release: Major study finds convalescent plasma doesn’t help seriously ill COVID-19 patients – McMaster University
Related:
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.
Commentary on Twitter
A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, according to a @NatureMedicine paper. https://t.co/7JFhEXLmbA pic.twitter.com/Q3e50Q0I7T
— Nature Portfolio (@NaturePortfolio) September 9, 2021
Face masks for COVID pass their largest test yet – “A rigorous study finds that surgical masks are highly protective, but cloth masks fall short”.
10 Sep, 2021 | 05:36h | UTCFace masks for COVID pass their largest test yet – Nature
Original study: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.
Commentary on Twitter
Face masks for COVID pass their largest test yet – I & others comment. It is true that I bought pink surgical masks (my favorite color) in response to this study for when I am around unvaccinated adults (or indoor public spaces for now)https://t.co/nFhlcqwrjv
— Monica Gandhi MD, MPH (@MonicaGandhi9) September 9, 2021
Covid-19: Infection increases the risk of kidney disease even in mild cases, finds study.
10 Sep, 2021 | 05:33h | UTCCovid-19: Infection increases the risk of kidney disease even in mild cases, finds study – The BMJ
Original study: Kidney Outcomes in Long COVID – Journal of the American Society of Nephrology
Long COVID and kidney disease.
10 Sep, 2021 | 05:31h | UTCLong COVID and kidney disease – Nature Reviews Nephrology
COVID infections may give more potent immunity than vaccines – but that doesn’t mean you should try to catch it.
10 Sep, 2021 | 05:29h | UTCOriginal study and commentary: [Preprint] Observational data suggests natural immunity after a SARS-CoV-2 infection confers longer lasting and stronger protection compared to vaccine-induced immunity.
India’s DNA COVID vaccine is a world first – more are coming.
10 Sep, 2021 | 05:30h | UTCIndia’s DNA COVID vaccine is a world first – more are coming – Nature
What an enormous global study can tell us about feeling better during the pandemic.
10 Sep, 2021 | 05:27h | UTCWhat an enormous global study can tell us about feeling better during the pandemic – Vox
Original study: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic – Nature Human Behavior
Perspective | What we actually know about waning immunity.
10 Sep, 2021 | 05:26h | UTCWhat We Actually Know About Waning Immunity – The Atlantic
[Preprint] Ineffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera.
9 Sep, 2021 | 10:02h | UTCIneffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera – bioRxiv
Related: United States boosts tracking of coronavirus strains as Mu variant draws scrutiny – Science
Commentary on Twitter (thread – click for more)
📍Bad news on #MuVariant—Japanese scientists: "Mu variant is highly resistant to sera from convalescent & [Pfizer]-vaccinated people. Direct comparison of different spike proteins revealed that Mu spike is more resistant…than all other current variants”🧵https://t.co/Ilf5gh3OGd pic.twitter.com/DbdJVGZTjz
— Eric Feigl-Ding (@DrEricDing) September 8, 2021
Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.
9 Sep, 2021 | 10:04h | UTCStudy 1: Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy – JAMA
Study 2: Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion – New England Journal of Medicine
Commentary on Twitter
📣 NO LINK BETWEEN MISCARRIAGE & COVID VACCINATION
This @JAMA_current study examined 105446 pregnancies, including 13160 miscarriages
Women with pregnancies ending in miscarriage were NOT more likely to have had 💉 in prior 28 days than those that didnthttps://t.co/7cFELq1oPM
— Ilan Schwartz is on🦋 (@GermHunterMD) September 8, 2021
[Preprint] RCT: Additional heterologous vs. homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination.
9 Sep, 2021 | 09:55h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1435720202147143680
AstraZeneca bosses warn against rush for boosters – “giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is “sensible”. But any decision to give a third, booster jab “to large swathes of the population”, to extend their protection from the first two, must be based on clinical data”.
9 Sep, 2021 | 09:59h | UTCAstraZeneca bosses warn against rush for boosters – BBC
Commentary on Twitter (thread – click for more)
"Moving too quickly to boost across the entire adult population will deprive us of these insights, leaving this important decision to rest on limited data," Mr Soriot and Sir Mene write.https://t.co/xTAk7yyu5G
— The Sharing Scientist (@ScienceShared) September 8, 2021
WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.
9 Sep, 2021 | 10:00h | UTCSee also:
WHO chief urges halt to booster shots for rest of the year – Associated Press
WHO extends moratorium on booster COVID vaccine doses – CIDRAP
Perspective | The plan to stop every respiratory virus at once – “The benefits of ventilation reach far beyond the coronavirus. What if we stop taking colds and flus for granted, too?”
9 Sep, 2021 | 09:54h | UTCThe Plan to Stop Every Respiratory Virus at Once – The Atlantic
Related:
Recommendations for ventilation of indoor spaces to reduce COVID-19 transmission.
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt.
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk
Balancing incentives and disincentives for vaccination in a pandemic.
9 Sep, 2021 | 09:52h | UTCBalancing incentives and disincentives for vaccination in a pandemic – Nature Medicine
A large observational study suggests eating a plant-rich diet could reduce the risk of developing severe COVID-19.
9 Sep, 2021 | 09:51h | UTCEating a plant rich diet reduces risk of developing COVID-19 – King’s College London
Original study: Diet quality and risk and severity of COVID-19: a prospective cohort study – Gut
Spread of Delta SARS-CoV-2 variant driven by a combination of immune escape and increased infectivity.
7 Sep, 2021 | 21:49h | UTCOriginal article: SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion – Nature
Cochrane review: evidence is insufficient to draw meaningful conclusions if SARS‐CoV‐2-specific monoclonal antibodies are effective in the treatment of COVID-19.
7 Sep, 2021 | 21:51h | UTCOriginal review: SARS‐CoV‐2‐neutralising monoclonal antibodies for treatment of COVID‐19 – Cochrane Library
Chile authorizes Sinovac vaccine for kids of 6 and older.
7 Sep, 2021 | 21:45h | UTCChile authorizes Sinovac vaccine for kids of 6 and older – Associated Press
Kids and COVID: why young immune systems are still on top.
7 Sep, 2021 | 21:46h | UTCKids and COVID: why young immune systems are still on top – Nature