Covid-19 | Page 19 of 100 | Links Medicus Content Curation & Alerts in Medicine

The acid test for Covid vaccines are protection of the elderly. New data from ~900,000 Finns age 70+ show how 3 shots achieved 96% effectiveness vs hospitalization, before and after Omicron, and even higher vs ICU need https://t.co/TQOQV4SL9a Spikevax=Moderna; Comirnaty=Pfizer pic.twitter.com/mtUCqne1dT

— Eric Topol (@EricTopol) March 14, 2022

COVID-19 and resilience of healthcare systems in ten countries.

15 Mar, 2022 | 10:02h | UTC

COVID-19 and resilience of healthcare systems in ten countries – Nature

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists.

15 Mar, 2022 | 09:51h | UTC

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists – La Radiologia Medica

Caring for older adults during the COVID-19 pandemic.

15 Mar, 2022 | 09:48h | UTC

Caring for older adults during the COVID-19 pandemic – Clinical Microbiology and Infection

Retrospective Cohort: Asthma in children and adolescents is not associated with increased risk of SARS-CoV-2 infection.

15 Mar, 2022 | 08:55h | UTC

Asthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents – Pediatrics

Commentary: Kids with asthma not at higher risk of COVID-19, study finds – CIDRAP

We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.

M-A: Asthma does not increase the risk of infection, hospitalization, ICU admission, and mortality from COVID-19

Systematic review: No evidence that patients with asthma are at increased risk of COVID-19 diagnosis, hospitalization or death

Asthma in COVID-19 hospitalizations: An overestimated risk factor?

Two years later, coronavirus evolution still surprises experts. Here’s why.

15 Mar, 2022 | 08:52h | UTC

Two years later, coronavirus evolution still surprises experts. Here’s why. – National Geographic

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far.

15 Mar, 2022 | 08:47h | UTC

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far – The Conversation

Effectiveness of contact tracing in the control of infectious diseases: a systematic review.

14 Mar, 2022 | 01:45h | UTC

Effectiveness of contact tracing in the control of infectious diseases: a systematic review – The Lancet Public Health

The changing epidemiology of SARS-CoV-2.

14 Mar, 2022 | 01:37h | UTC

The changing epidemiology of SARS-CoV-2 – Science

Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression.

14 Mar, 2022 | 01:44h | UTC

Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression – The Lancet

Commentaries:

Review of pre-Omicron data finds COVID-19 vaccine protection from severe disease remains strong at six months – Johns Hopkins University Bloomberg School of Public Health

Waning of COVID-19 vaccine effectiveness: individual and public health risk – The Lancet

Stopping pandemics before they start: Lessons learned from SARS-CoV-2.

14 Mar, 2022 | 01:38h | UTC

Stopping pandemics before they start: Lessons learned from SARS-CoV-2 – Science

Review: Post-acute COVID-19 syndrome.

14 Mar, 2022 | 01:34h | UTC

Post-acute COVID-19 syndrome – European Respiratory Journal

ESCMID rapid guidelines for assessment and management of long COVID.

ERS statement on Long COVID-19 follow-up.

Proposed subtypes of long-Covid and their respective potential therapies.

EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.

Global surveillance, research, and collaboration needed to improve understanding and management of long COVID.

Provocative study suggests that persistent physical symptoms after COVID-19 infection may be associated more with the belief in having been infected with SARS-CoV-2 than with having laboratory-confirmed COVID-19 infection.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)

Systematic Review: Inhaled corticosteroids for the treatment of COVID‐19.

11 Mar, 2022 | 10:18h | UTC

Inhaled corticosteroids for the treatment of COVID‐19 – Cochrane Library

[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.

PRINCIPLE RCT: Inhaled budesonide improves time to recovery from COVID-19 in people at high risk of complications in the community.

Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.

RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19

Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

Commentary on Twitter (thread – click for more)

https://twitter.com/CochraneLibrary/status/1501615982208507912

WHO Guidance: Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing.

11 Mar, 2022 | 10:20h | UTC

Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing – World Health Organization

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21.

11 Mar, 2022 | 10:16h | UTC

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21 – The Lancet

News Release: Global death toll of COVID-19 pandemic may be more than three times higher than official records, estimates of excess deaths indicate – The Lancet

Commentaries:

COVID’s true death toll: far higher than official records – Nature

Covid deaths probably three times higher than records say – BBC

Editorial: “Excess deaths” is the best metric for tracking the pandemic.

The pandemic’s true death toll: millions more than official counts.

We can be confident there have been far more than 5 million global Covid deaths – “Estimating ‘excess’ fatalities, a more robust analysis method, puts the pandemic’s grim toll between 10m and 19m people”.

Global Covid-19 deaths surpass five million.

Effects of the Covid-19 pandemic on life expectancy and premature mortality in 2020 – this time series analysis showed there were more than 28 million excess years of life lost in 2020 in 31 countries.

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

Commentary on Twitter

https://twitter.com/EricTopol/status/1502064507597860872

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for.

11 Mar, 2022 | 10:07h | UTC

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for – The Conversation

Another study suggests that a third vaccine dose is necessary to protect populations against the omicron variant.

11 Mar, 2022 | 10:14h | UTC

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study – The BMJ

News Release: Third vaccine dose critical for protecting populations against omicron variant – BMJ Newsroom

Commentary on Twitter

mRNA vaccines are highly effective in preventing covid-19 associated hospital admissions related to the alpha, delta, and omicron variants. But three doses are needed to achieve a similar level of protection against omicron, finds a large US study: https://t.co/YMm176gmby

— The BMJ (@bmj_latest) March 10, 2022