Antibiotic Stewardship
M-A: Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients.
29 Sep, 2021 | 10:24h | UTC
Podcast: Neutropenic Fever.
28 Sep, 2021 | 08:52h | UTC#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo – The Curbsiders
Less common bacterial, fungal and viral infections: review of management in the pregnant patient.
26 Sep, 2021 | 21:38h | UTC
Antibiotic Overuse and Stewardship at Hospital Discharge: The Reducing Overuse of Antibiotics at Discharge (ROAD) Home Framework.
26 Sep, 2021 | 21:40h | UTC
Commentary on Twitter
Looking to improve antibiotic use at discharge? Check out our ROAD Home Framework: Reducing Overuse of Antibiotics at Discharge Home. 🔥🔥🔥 at CID. https://t.co/mTKlaNerpC Excited for my first pub with the amazing @EmilySpivak and Adam Hersh! #stewarship @IDSAInfo pic.twitter.com/BMkD1M6Rqs
— Valerie Vaughn (@ValerieVaughnMD) September 23, 2021
RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.
24 Sep, 2021 | 09:00h | UTC
Commentary on Twitter
#Antibiotic resistance is a global public health threat.
New trial indicates, unless pneumonia is suspected, clinicians should provide safety-netting advice but not prescribe antibiotics for most children presenting with chest infections. https://t.co/mOwLG5rZd1 #AMR pic.twitter.com/b0c7Z5flQk
— The Lancet (@TheLancet) September 23, 2021
WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.
24 Sep, 2021 | 08:53h | UTC
RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.
22 Sep, 2021 | 10:03h | UTCEffect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)
Cluster RCT: Procalcitonin point-of-care testing may reduce antibiotic prescription for patients with suspected lower respiratory tract infection in primary care.
22 Sep, 2021 | 10:01h | UTC
Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.
22 Sep, 2021 | 10:02h | UTC
Large cohort study suggests routine replacement (every 96 hours) of peripheral intravenous catheters may reduce the risk of bloodstream infections compared to clinically indicated replacement.
19 Sep, 2021 | 23:34h | UTCComparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters – JAMA Internal Medicine (free for a limited period)
Related Cochrane Review with different findings: Systematic Review: Clinically‐indicated vs. Routine Replacement of Peripheral Venous Catheters
Commentary on Twitter
Phlebitis due to peripheral venous catheters is not a proxy for bloodstream infection. A large prospective study shows that clinically indicated replacement of peripheral venous catheters may put patients at risk of bloodstream infection https://t.co/SNo4SpfoKE
— JAMA Internal Medicine (@JAMAInternalMed) September 17, 2021
As Covid Cases Rise, So Do Hospital-Related Infections.
17 Sep, 2021 | 10:08h | UTCAs Covid Cases Rise, So Do Hospital-Related Infections – Wired
A guide to the treatment of cellulitis and other soft-tissue infections.
16 Sep, 2021 | 09:47h | UTCA guide to the Tx of cellulitis and other soft-tissue infections – Journal of Family Practice
Antifungal Susceptibility Testing: A Primer for Clinicians.
14 Sep, 2021 | 08:46h | UTCAntifungal Susceptibility Testing: A Primer for Clinicians – Open Forum Infectious Diseases
Commentary on Twitter
New in OFID: An overview for clinicians on antifungal susceptibility testing, including testing methods and their limitations, and how results may or may not be clinically useful.
📄:https://t.co/ZhPL5oQ57F #OpenForumInfectDis #IDSAJournals @PaulSaxMD @DrJLi pic.twitter.com/wrIkBc5MPV
— IDSA (@IDSAInfo) September 11, 2021
RCT: A Seven-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales was noninferior to a 14-days course.
9 Sep, 2021 | 09:03h | UTC
Commentary on Twitter
SHORTEN RCT 🔥🔥🔥@CMIJournal
Seven versus 14-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales
7-day course of antibiotics as the preferential treatment for eBSI, as long as the source is properly controlled https://t.co/pyaOMl52us pic.twitter.com/wK1sgeMe36— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 8, 2021
Antibiotics use is linked to increased risk of subsequent colorectal cancer.
7 Sep, 2021 | 21:25h | UTCCommentaries:
Antibiotics linked to increased risk of colon cancer – Umea University
Study links antibiotics use and increased subsequent risk of colorectal cancer – MedicalResearch.com
Annual Update in Intensive Care and Emergency Medicine 2021 – Covid articles.
7 Sep, 2021 | 10:50h | UTCSecondary infections in critically ill patients with COVID-19
Tracheostomy for COVID-19: evolving best practice
See also: Non-Covid articles
Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review - short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.
2 Sep, 2021 | 08:19h | UTCTreatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics
World leaders and experts call for significant reduction in the use of antimicrobial drugs in global food systems.
2 Sep, 2021 | 08:13h | UTCCommentary: Global group urges limits on antimicrobials in food production – CIDRAP
M-A mostly of observational studies found that in patients with Methicillin-Resistant Staphylococcus aureus Bloodstream Infection Daptomycin was associated with a lower risk of clinical failure than Vancomycin, without differences in mortality.
2 Sep, 2021 | 08:10h | UTC
Review: Initial antimicrobial management of sepsis – immediate, empiric, broad-spectrum therapy is key, but it must be accompanied by a commitment to de-escalation and antimicrobial stewardship.
1 Sep, 2021 | 08:59h | UTCInitial antimicrobial management of sepsis – Critical Care
COVID-19 associated Mucormycosis: risk factors and mechanisms of disease.
27 Aug, 2021 | 10:07h | UTCRelated: Clinical Picture: Mucormycosis after COVID-19 in a patient with diabetes. (several articles on the subject)
Commentary on Twitter
🆕💥💥Review Article #CID @IDSAInfo @jobadd
COVID-19 associated Mucormycosis (CAM): risk factors and mechanisms of disease #IDTwitter #medtwitter #TwitteRx https://t.co/Ob89SFNoPx pic.twitter.com/tzf7KpGVyG— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) August 22, 2021
Global guideline for the diagnosis and management of rare yeast infections.
27 Aug, 2021 | 09:08h | UTC
Commentary on Twitter
The @eurconfmedmycol did it again!
The 4⃣th One World🌍- One Guideline is published!
This time for the Diagnosis and Management of RARE YEAST Infections
Free access🔗https://t.co/1QSanohMsk @TheLancetInfDis@CornelyOliver @neleshg @ASMicrobiology @ISHAM_Mycology @martinhoenigl pic.twitter.com/DEnS09MnDS— Rosanne Sprute (@RosanneSprute) August 20, 2021
Study: Macrolide use significantly associated with both prevalent and incident tinnitus.
22 Aug, 2021 | 22:11h | UTCCommentary: Macrolide Use and Tinnitus: A New Safety Ringtone? – NEJM Journal Watch (free for a limited period)
Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.
20 Aug, 2021 | 08:41h | UTC
Metrics for evaluating antibiotic use and prescribing in outpatient settings.
20 Aug, 2021 | 08:40h | UTC