Hematology (all articles)
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
11 Jul, 2017 | 16:54h | UTCCommentary: Adding Midostaurin to Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia With FLT3 Mutation – ASCO Post (free)
Direct oral anticoagulants for treatment of Heparin-induced Thrombocytopenia
9 Jul, 2017 | 00:35h | UTCDirect oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review – Blood (link to abstract – $ for full-text)
Source: Direct Oral Anticoagulants for Heparin-Induced Thrombocytopenia – Journal Watch ($)
This literature review and observational study suggest direct oral anticoagulants (rivaroxaban, apixaban, dabigatran) are safe and effective for the treatment of Heparin-induced Thrombocytopenia.
Benefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia
7 Jul, 2017 | 13:59h | UTCBenefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Review Questions Antithrombotic Tx in Essential Thrombocythemia – Physician’s Briefing (free)
Guidelines for the use of imaging in the management of myeloma
7 Jul, 2017 | 14:00h | UTCGuidelines for the use of imaging in the management of myeloma – British Journal of Haematology (free)
Emerging therapies for acute myeloid leukemia
7 Jul, 2017 | 13:47h | UTCReview: Emerging therapies for acute myeloid leukemia – Journal of Hematology & Oncology (free)
Peri-operative blood management
7 Jul, 2017 | 13:43h | UTCReview: Peri-operative blood management – Indian Journal of Anesthesia (free)
Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia
7 Jul, 2017 | 13:30h | UTCReview: Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia – Frontiers in Immunology (free)
Reduced-intensity versus myeloablative allogeneic transplantation
3 Jul, 2017 | 17:39h | UTC
Hematopoietic stem cell transplantation for sickle cell anemia
3 Jul, 2017 | 17:40h | UTC
Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation
3 Jul, 2017 | 17:38h | UTC
Hematopoietic cell transplantation for acute lymphoblastic leukemia in adult patients
3 Jul, 2017 | 17:41h | UTC
Long-term complications after hematopoietic cell transplantation
3 Jul, 2017 | 17:35h | UTC
Direct oral anticoagulants in patients with chronic kidney disease
3 Jul, 2017 | 17:27h | UTC
A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery
26 Jun, 2017 | 17:32h | UTCA Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery – Annals of Surgery (link to abstract – $ for full-text)
Source: EvidenceAlerts (free resource to find articles of interest)
“Antiplatelet therapy at the time of noncardiac surgery confers minimal bleeding risk with no difference in thrombotic complications. In many cases, it is safe to continue antiplatelet therapy in patients with important indications for their use”
Nucleated RBCs may be a predictor of post-discharge mortality and unplanned hospital readmission
21 Jun, 2017 | 18:27h | UTC“Presence of nucleated RBCs is a robust predictor of post-discharge mortality and unplanned hospital readmission” (RT @Crit_Care see Tweet)
Antiplatelet Therapy in Patients With Coronary Stents Undergoing Elective Noncardiac Surgery
20 Jun, 2017 | 18:23h | UTCNew Insight Into the Biology, Risk Stratification, and Targeted Treatment of Myelodysplastic Syndromes
16 Jun, 2017 | 01:31h | UTC
Chronic Myeloid Leukemia: What Every Practitioner Needs to Know in 2017
16 Jun, 2017 | 01:26h | UTCChronic Myeloid Leukemia: What Every Practitioner Needs to Know in 2017 – 2017 ASCO Educational Book (free)
Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction
15 Jun, 2017 | 00:50h | UTCNon–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentary: NOAC Doses: Just Stick to the Label – MedPage Today (free registration required)
“Among the 1,473 patients with a renal indication for dose reduction, 43.0% were potentially overdosed, which was associated with a higher risk of major bleeding”
World Blood Donor Day (June 14, 2017)
15 Jun, 2017 | 00:52h | UTCWorld Blood Donor Day (June 14, 2017) – World Health Organization (free)
See also: 10 facts on blood transfusion (free) AND Giving blood in a time of crisis (free) AND WHO’s work on blood transfusion safety (free)
Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex for Iron-Deficiency Anemia
15 Jun, 2017 | 00:48h | UTCEffect of Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex on Hemoglobin Concentration in Young Children With Nutritional Iron-Deficiency Anemia: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
The JAMA Network – For the Media: Treating Nutritional Iron-Deficiency Anemia in Children (free)
Commentaries: Ferrous Sulfate Drops Tied to Higher Hemoglobin Increases in Kids with Anemia – Physician’s First Watch (free) AND Traditional treatment is better for iron-deficiency anaemia in children – OnMedica (free) AND Ferrous Sulfate Effective for Iron-Deficiency Anemia in Kids – Medscape (free registration required)
Researchers expected that Iron Polysaccharide Complex would restore hemoglobin more effectively, because it is designed to be tolerated better, but the proportion of infants and children with a complete resolution of iron-deficiency anemia was higher in the ferrous sulfate group (29 percent vs 6 percent).
Iron deficiency or anemia of inflammation?
4 Jun, 2017 | 19:07h | UTC
HUS and atypical HUS
4 Jun, 2017 | 19:02h | UTCReview: HUS and atypical HUS – Blood (free)
Source: Critical Care Reviews Newsletter
Heparin-induced thrombocytopenia
4 Jun, 2017 | 19:03h | UTCReview: Heparin-induced thrombocytopenia – Blood (free)
Source: Critical Care Reviews Newsletter
Clinical updates in adult immune thrombocytopenia
4 Jun, 2017 | 19:03h | UTCClinical updates in adult immune thrombocytopenia – Blood (free)
Source: Critical Care Reviews Newsletter