Hematology (all articles)

“Global incident cases of multiple myeloma more than doubled from 1990-2016 w/incident cases increasing by 126%. The largest increase was in middle-SDI countries, particularly E. Asia with a 262% increase in incidence cases”. (via @IHME_UW see Tweet)

Guideline: Management of Mantle Cell Lymphoma

18 May, 2018 | 02:40h | UTC

Guideline for the management of mantle cell lymphoma – British Journal of Haematology (free)

Randomized Controlled Trial: Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage

18 May, 2018 | 02:36h | UTC

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial – The Lancet (free)

Editorial: Haemostatic treatment for intracerebral haemorrhage (free)

Commentaries: Study: Drug to treat bleeding may reduce stroke deaths – UPI (free) AND Drug to treat bleeding may benefit some stroke patients, study finds – University of Nottingham, via EurekAlert (free)

Study: Testing Blood Donations for Zika Virus is Costly and Finds Few Infections

15 May, 2018 | 09:36h | UTC

Investigational Testing for Zika Virus among U.S. Blood Donors – New England Journal of Medicine (free)

Quick Take Video Summary: Testing Blood Donations for Zika Virus (free)

Sounding Board: Revisiting Blood Safety Practices Given Emerging Data about Zika Virus (free)

Commentaries: Study: Zika blood donation screening costly, finds few cases – CIDRAP (free) AND Testing for Zika virus in blood donors finds few infections — at a cost of about $5.3 million each – STAT (free)

Guideline: Investigation and Management of a Raised Serum Ferritin

10 May, 2018 | 17:43h | UTC

Guideline: Investigation and management of a raised serum ferritin – British Journal of Haematology (free)

Guideline: Use of Hydroxycarbamide in Patients with Sickle Cell Disease

9 May, 2018 | 16:19h | UTC

Guidelines for the use of hydroxycarbamide in children and adults with sickle cell disease – British Journal of Haematology (free)

Review: Chronic Lymphocytic Leukemia

9 May, 2018 | 16:15h | UTC

Chronic Lymphocytic Leukemia: Diagnosis and Treatment – Mayo Clinic Proceedings (free)

Meta-Analysis: Direct Oral Anticoagulant vs Low-Molecular-Weight Heparin in Cancer Associated Thrombosis

4 May, 2018 | 01:59h | UTC

Direct oral anticoagulant (DOAC) versus low-molecular-weight heparin (LMWH) for treatment of cancer associated thrombosis (CAT): A systematic review and meta-analysis – Thrombosis Research (free)

Source: EvidenceAlerts

Things We Do For No Reason: Periprocedural Bridging Anticoagulation

27 Apr, 2018 | 01:25h | UTC

Things We Do For No Reason: Periprocedural Bridging Anticoagulation – Journal of Hospital Medicine (free)

Guideline: Vaccination Strategies in Patients with Hematologic Malignancies or Solid Tumors

27 Apr, 2018 | 01:13h | UTC

Anti-infective Vaccination Strategies in Patients with Hematologic Malignancies or Solid Tumors – Guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) – Annals of Oncology (free)

Research: Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

24 Apr, 2018 | 18:04h | UTC

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study reveals subtypes of lymphoma – NIH Research Matters (free)

Systematic Review: Antifibrinolytics for Heavy Menstrual Bleeding

24 Apr, 2018 | 17:58h | UTC

Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

Research :Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

20 Apr, 2018 | 01:57h | UTC

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia – New England Journal of Medicine (free)

Editorial: Gene Therapy as a Curative Option for β-Thalassemia (free)

Quick Take Video Summary: LentiGlobin Gene Therapy for β-Thalassemia (free)

Commentaries: Gene therapy could free some people from a lifetime of blood transfusions – MIT Technology Review (free) AND Gene Therapy For Inherited Blood Disorder Reduced Transfusions – NPR (free) AND Expert reaction to study on gene therapy for beta-thalassaemia – Science Media Centre (free)

Commentary: Oral vs. Intramuscular Vitamin B₁₂: Efficacy, Safety Compared – MPR (free)

BSH Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products

22 Mar, 2018 | 23:50h | UTC

British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding – British Journal of Haematology (free)

ASCO 2018: Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia

ESMO Guideline: Hodgkin lymphoma

Review: Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease

Systematic Review: Incidence of Venous thromboembolism and Use of Anticoagulation in Hematological Malignancies

Review: Pathogenesis and Diagnosis of Disseminated Intravascular Coagulation

Review: Laboratory Diagnosis of Platelet Function Disorders

Review: A Causal Mechanism for Childhood Acute Lymphoblastic Leukemia

Report: Global Burden of Multiple Myeloma