Hematology (all articles)
Study: Testosterone Therapy Linked to Increased Risk of Venous Thromboembolism Among Men with and Without Hypogonadism
12 Nov, 2019 | 11:22h | UTCAssociation of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Using testosterone therapy in 6-month case period associated with doubling of VTE risk for men both with and without clinical hypogonadism. https://t.co/rosKWgWgBS
— JAMA Internal Medicine (@JAMAInternalMed) November 11, 2019
[Abstract Only] Randomized Trial: Treatments for Relapsed or Refractory FLT3-mutated Acute Myeloid Leukemia Compared
10 Nov, 2019 | 12:57h | UTCGilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ADMIRAL: Gilteritinib vs Chemotherapy in Relapsed or Refractory FLT3-Mutated AML – The ASCO Post (free)
Randomized Trial: Levofloxacin Prophylaxis Reduces Early Deaths in Patients with Newly Diagnosed Myeloma
30 Oct, 2019 | 08:17h | UTCCommentaries: Reducing infection-related morbidity and mortality in patients with myeloma – The Lancet Oncology (free) AND Abx Prophylaxis Cuts Early Death in Newly Diagnosed Myeloma – MedPage Today (free)
Randomized Trial: Treatment vs. Observation in Smoldering Multiple Myeloma
30 Oct, 2019 | 08:15h | UTCCommentary: Lenalidomide may delay onset of myeloma-related bone, organ damage – Mayo Clinic (free)
[Abstract Only] Study: The Global Need and Availability of Blood Products
25 Oct, 2019 | 08:40h | UTCThe global need and availability of blood products: a modelling study – The Lancet Haematology (link to abstract – $ for full-text)
Commentaries: Hospitals Around The World Have A Dire Shortage Of Blood – NPR (free) AND 61% of countries have insufficient blood supplies – OnMedica (free)
Hemolytic Uremic Syndrome: Diagnosis and Management
23 Oct, 2019 | 07:24h | UTCHaemolytic uremic syndrome: diagnosis and management – F1000Research (free)
Source: Critical Care Reviews Newsletter
Randomized Trial: Fibrinogen Concentrate vs. Cryoprecipitate for the Treatment of Bleeding in Cardiac Surgery
22 Oct, 2019 | 07:36h | UTCEffect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Should Fibrinogen Concentrate Replace Cryoprecipitate in Cardiac Surgery? (free for a limited period)
[Abstract Only] Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome
15 Oct, 2019 | 10:32h | UTCRivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)
Consensus Statement for the Diagnosis and Evaluation of Adult Patients With Histiocytic Neoplasms
10 Oct, 2019 | 09:08h | UTC
NCCN Guidelines Insights: Multiple Myeloma
10 Oct, 2019 | 09:05h | UTCNCCN Guidelines Insights: Multiple Myeloma, Version 1.2020 – National Comprehensive Cancer Network (free)
NCCN Guideline: Distress Management
10 Oct, 2019 | 09:06h | UTC
UK Guidelines on the Management of Iron Deficiency in Pregnancy
8 Oct, 2019 | 10:16h | UTCUK guidelines on the management of iron deficiency in pregnancy – British Journal of Haematology (free)
Expert Statement on the ICU Management of Thrombotic Thrombocytopenic Purpura
8 Oct, 2019 | 10:09h | UTCRelated Guidelines: Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies – British Journal of Haematology (free) AND Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan – International Journal of Hematology (free) AND Consensus opinion on diagnosis and management of thrombotic microangiopathy in Australia and New Zealand – Nephrology (free)
AL Amyloidosis for the Cardiologist and Oncologist: Epidemiology, Diagnosis, and Management
2 Oct, 2019 | 22:15h | UTCRelated: Cardiac Amyloidosis: Updates in Imaging (several reviews on the subject)
Guideline Synopsis: Prevention and Management of Venous Thromboembolism
25 Sep, 2019 | 08:33h | UTCPrevention and Management of Venous Thromboembolism – JAMA (free for a limited period)
Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)
Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)
Meta-analysis: Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke
25 Sep, 2019 | 08:13h | UTC
Systematic Review: Non‐steroidal Anti‐inflammatory Drugs for Heavy Menstrual Bleeding
24 Sep, 2019 | 08:10h | UTCNon‐steroidal anti‐inflammatory drugs for heavy menstrual bleeding – Cochrane Library (free)
Summary: Are non-steroidal anti-inflammatory drugs safe and effective for treating heavy menstrual bleeding? – Cochrane Library (free)
[Abstract Only] Study: The Prevalence of Hemophilia is Higher than Previously Estimated
24 Sep, 2019 | 07:49h | UTCEstablishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Hemophilia three times more prevalent than thought – McMaster University (free) AND 1,125,000 Men/Boys Expected to Have Hemophilia Worldwide – Clinical Advisor (free) AND Prevalence of Hemophilia Worldwide Is Triple That of Previous Estimates, New Study Says – AJMC (free)
Guideline: Diagnosis of Chronic Anemia in Gastrointestinal Disorders
23 Sep, 2019 | 01:09h | UTC
#ESCCongress – 2019 ESC Guidelines for the Diagnosis and Management of Acute Pulmonary Embolism
2 Sep, 2019 | 01:19h | UTC
Related Commentary on Twitter
JUST RELEASED: 2019 #ESCGuidelines for Acute Pulmonary Embolism – what's new? what has changed? what are the main 2019 recommendations? https://t.co/nyLf7eWk5G@escardio #ESCcongress #ESCCoT #cardiotwitter pic.twitter.com/DEFBMKdwcO
— European Society of Cardiology (@escardio) August 31, 2019
Randomized Trial: Effect of Low-Dose Vasopressin on Need for Transfusions in Patients With Trauma and Hemorrhagic Shock
29 Aug, 2019 | 06:45h | UTCEffect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentaries: Vasopressin as an Early Adjunct to Resuscitation in Hemorrhagic Shock: Crisis AVERTed? – JAMA Surgery (free) AND Giving trauma patients blood pressure stabilizing hormone cuts transfusions by half – University of Pennsylvania School of Medicine (free)
Author Interview: Arginine Vasopressin Supplementation in Early Traumatic Shock (free)
“Additional research is necessary to determine whether including AVP improves morbidity or mortality.”
ACOG Recommendations: Screening and Management of Bleeding Disorders in Adolescents with Heavy Menstrual Bleeding
28 Aug, 2019 | 02:30h | UTCCommentary: ACOG advises bleeding disorder screening for teens with heavy menstruation – ObGyn News (free)
Podcast: Common Complete Blood Count (CBC) Abnormalities
28 Aug, 2019 | 02:13h | UTC#167 LIVE! Common CBC Abnormalities with Mary Kwok MD – The Curbsiders Internal Medicine Podcast (free)
Cardiac Amyloidosis: Updates in Imaging
27 Aug, 2019 | 00:21h | UTCCardiac Amyloidosis: Updates in Imaging – Current Cardiology Reports (free)
Related Reviews: AL (Light-Chain) Cardiac Amyloidosis: A Review of Diagnosis and Therapy – Journal of the American College of Cardiology (free) Contemporary Imaging Diagnosis of Cardiac Amyloidosis – Journal of Cardiovascular Imaging (free) AND Progress in diagnosing and managing cardiac amyloidosis – Cleveland Clinic Journal of Medicine (free) AND Role of cardiovascular imaging for the diagnosis and prognosis of cardiac amyloidosis – openheart (free) AND Recent advances in diagnosis and treatment of cardiac amyloidosis – Journal of Cardiology (free) AND Cardiac Amyloidosis: An Update on Pathophysiology, Diagnosis, and Treatment – Trends in Cardiovascular Medicine (free)
Mendelian Randomization Study: Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease
25 Aug, 2019 | 21:28h | UTC