Hematology (all articles)
EASL Clinical Practice Guidelines on hemochromatosis.
18 Jul, 2022 | 11:47h | UTCEASL Clinical Practice Guidelines on haemochromatosis – Journal of Hepatology
RCT | Overall survival with Brentuximab Vedotin in stage III or IV Hodgkin’s lymphoma.
18 Jul, 2022 | 11:13h | UTCOverall Survival with Brentuximab Vedotin in Stage III or IV Hodgkin’s Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Brentuximab vedotin may improve overall survival in patients with Hodgkin Lymphoma – Mayo Clinic
The EBMT nursing guidelines on CAR-T Therapy | A framework for patient care and managing common toxicities.
14 Jul, 2022 | 12:45h | UTC
Review | Cardiovascular disease in myeloproliferative neoplasms.
14 Jul, 2022 | 12:38h | UTC
Single-arm study | Long-term benefits of Tagraxofusp for patients with blastic plasmacytoid dendritic cell neoplasm.
14 Jul, 2022 | 12:13h | UTCRelated Study: Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm – New England Journal of Medicine
RCT | Neutropenic versus regular diet for acute leukemia induction chemotherapy.
13 Jul, 2022 | 11:45h | UTCNeutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Related:
Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer – European Journal of Cancer (link to abstract – $ for full-text)
Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (PDF)
M-A | Oral iron supplementation in patients with heart failure.
13 Jul, 2022 | 11:17h | UTC
ESAIC/ESRA guideline | Regional anesthesia in patients on antithrombotic drugs.
11 Jul, 2022 | 12:46h | UTC
Commentary on Twitter
https://twitter.com/preopconsult/status/1546157273856315392
RCT | Zanubrutinib vs. bendamustine and rituximab in untreated chronic lymphocytic leukemia and small lymphocytic lymphoma.
11 Jul, 2022 | 11:49h | UTCZanubrutinib versus bendamustine and rituximab in untreated chronic lymphocytic leukaemia and small lymphocytic lymphoma (SEQUOIA): a randomised, controlled, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.
8 Jul, 2022 | 11:59h | UTC
Clinical recommendations to diagnose and monitor patients with transthyretin amyloid cardiomyopathy.
8 Jul, 2022 | 11:53h | UTCRelated:
AHA Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis.
RCT | Efficacy and safety of a Pegasparaginase-based chemotherapy regimen vs. an L-asparaginase–based chemotherapy regimen for newly diagnosed advanced extranodal Natural Killer/T-Cell Lymphoma.
8 Jul, 2022 | 11:21h | UTCEfficacy and Safety of a Pegasparaginase-Based Chemotherapy Regimen vs an L-asparaginase–Based Chemotherapy Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Editorial: De-escalating Chemotherapy for Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Step Toward Improved Treatment of a Rare Virus-Associated Cancer – JAMA Oncology (free for a limited period)
See also: Visual Abstract
Review | Sickle cell disease.
7 Jul, 2022 | 12:59h | UTCSickle Cell Disease: A Review – JAMA (free for a limited period)
Audio Clinical Review: Sickle Cell Disease – JAMA
Coagulation and transfusion updates from 2021.
7 Jul, 2022 | 12:36h | UTCCoagulation and Transfusion Updates from 2021 – Journal of Cardiothoracic and Vascular Anesthesia
M-A | DOACs vs. VKAs in atrial fibrillation patients with bioprosthetic heart valve.
7 Jul, 2022 | 12:15h | UTC
M-A | Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital.
5 Jul, 2022 | 12:19h | UTCCohort Study | Treatment outcomes and roles of transplantation and maintenance rituximab in patients with previously untreated mantle cell lymphoma.
5 Jul, 2022 | 11:39h | UTCNews Release: Mantle cell lymphoma treatment varies according to setting – Weill Cornell Medicine
EM Cases | The 7 Ts of massive hemorrhage protocols.
5 Jul, 2022 | 11:35h | UTCEM Cases: The 7 Ts of Massive Hemorrhage Protocols – emDocs
RCT | CT vs. [18F]FDG-PET-CT for persistent or recurrent neutropenic fever in high-risk patients.
4 Jul, 2022 | 12:21h | UTC[18F]FDG-PET-CT compared with CT for persistent or recurrent neutropenic fever in high-risk patients (PIPPIN): a multicentre, open-label, phase 3, randomised, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)
Commentary on Twitter
NEW research: [18F]FDG-PET-CT resulted in more frequent antimicrobial rationalisation than CT in patients w/ haem diseases & persistent/recurrent high-risk neutropenic fever after chemotherapy. Results of the ph3 RCT PIPPIN #radonc #hemonc https://t.co/isOPFZVVpY pic.twitter.com/PVd8yFy7Ck
— The Lancet Haematology (@TheLancetHaem) June 29, 2022
FDA warns about possible increased risk of death and serious side effects with duvelisib.
4 Jul, 2022 | 11:51h | UTC2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.
1 Jul, 2022 | 11:50h | UTCRelated:
Editorial | Circulating tumor cell burden as a component of staging in multiple myeloma: ready for prime time?
4 Jul, 2022 | 11:48h | UTCOriginal Studies:
Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.
1 Jul, 2022 | 11:49h | UTCCommentaries:
Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)
Commentary on Twitter (thread – click for more)
Early in the pandemic we wondered whether antithrombotic therapy in outpatients with #COVID19 would prevent #thrombosis ❓
Several trials were started globally and the ACTIV-4B trial was previously reported⬇️ https://t.co/Q15WcZwDIA
Now, we publish the OVID and ETHIC trials🧵
— The Lancet Haematology (@TheLancetHaem) June 30, 2022
RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.
30 Jun, 2022 | 10:50h | UTCProthrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary on Twitter
https://twitter.com/JAMASurgery/status/1542176079728738305
Single-arm phase II study: Venetoclax added to Cladribine plus low-dose Cytarabine alternating with 5-Azacitidine in older patients with newly diagnosed acute myeloid leukemia.
30 Jun, 2022 | 10:14h | UTCPhase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia – Journal of Clinical Oncology (link to abstract – $ for full-text)