General Hematology | Page 4 of 17 | Links Medicus Content Curation & Alerts in Medicine

Review | Platelet aggregation inhibitors and anticoagulants in gastroenterological and visceral surgical procedures

1 Mar, 2023 | 14:03h | UTC

Platelet Aggregation Inhibitors and Anticoagulants in Gastroenterological and Visceral Surgical Procedures – Deutsches Ärzteblatt international

Review | Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

28 Feb, 2023 | 14:00h | UTC

Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management – The BMJ

Single-arm study | Two-year outcomes of Valoctocogene Roxaparvovec therapy for Hemophilia A

27 Feb, 2023 | 12:51h | UTC

Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary on Twitter

In the GENEr8-1 trial, participants with hemophilia A received B-domain–deleted factor VIII gene therapy delivered in an AAV5 vector. A decrease in annualized bleeding rates was maintained for 2 years despite declining factor VIII levels. https://t.co/hYy3pT8ssa #hematology pic.twitter.com/HuJQa0HiTR

— NEJM (@NEJM) February 23, 2023

M-A | COVID-19 convalescent plasma outpatient therapy may prevent hospitalizations

23 Feb, 2023 | 13:37h | UTC

Convalescent Plasma Outpatient Therapy to Prevent Outpatient Hospitalization: A Meta-analysis of Individual Participant Data From Five Randomized Trials – Clinical Infectious Diseases

Commentary: New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment – News Medical

Review | How to manage coagulopathies in critically ill patients

21 Feb, 2023 | 11:43h | UTC

How to manage coagulopathies in critically ill patients – Intensive Care Medicine

Commentary on Twitter

Coagulopathies severe/frequent complication in #ICU: how to manage??
? hemorrhagic coagulopathies: non‑malignant & malignant
? thrombotic c.: sepsis‑induced & solid cancer‑associated
? managing hemorrhagic c.
?(preventing &) managing thrombotic c.
?️ https://t.co/CKqzT7dcoH pic.twitter.com/SvpPNf0oGO

— Intensive Care Medicine (@yourICM) February 18, 2023

RCT | Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy

14 Feb, 2023 | 10:31h | UTC

Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy: A randomised controlled trial – BJOG

M-A | Efficacy and safety of treatments in newly diagnosed adult primary immune thrombocytopenia

9 Feb, 2023 | 13:30h | UTC

Efficacy and safety of treatments in newly diagnosed adult primary immune thrombocytopenia: A systematic review and network meta-analysis – eClinicalMedicine

M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients

7 Feb, 2023 | 14:06h | UTC

The Effect of Heparin Full-Dose Anticoagulation on Survival of Hospitalized, Non-critically Ill COVID-19 Patients: A Meta-analysis of High Quality Studies – Lung

#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Efficacy and safety of heparin full-dose anticoagulation in hospitalized non-critically ill COVID-19 patients: a meta-analysis of multicenter randomized controlled trials – Journal of Thrombosis and Thrombolysis

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

Podcast | Hemochromatosis pearls

7 Feb, 2023 | 13:53h | UTC

#380 Hemochromatosis with Elliot Tapper – The Curbsiders

Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit

3 Feb, 2023 | 14:15h | UTC

Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit – Intensive Care Medicine

Commentary on Twitter

? Eosinophilia? Not uncommon in #ICU! Depending on timing, 2 subsets of pts, corresponding to different underlying diseases/different patterns of eosinophil-induced organ damage & requiring different etiological workups/management can be distinguished.
?️ https://t.co/nr1EHHnYGa pic.twitter.com/VBWpJKUGrv

— Intensive Care Medicine (@yourICM) February 2, 2023

Transfusion thresholds for acute coronary syndromes — insights from the TRICS‐III trial and meta‐analysis

3 Feb, 2023 | 13:58h | UTC

Transfusion Thresholds for Acute Coronary Syndromes—Insights From the TRICS‐III Randomized Controlled Trial, Systematic Review, and Meta‐Analysis – Journal of the American Heart Association

RCT | Effects of once-weekly prophylaxis with Efanesoctocog Alfa in patients with severe Hemophilia A

30 Jan, 2023 | 01:14h | UTC

Efanesoctocog Alfa Prophylaxis for Patients with Severe Hemophilia A – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Once-Weekly Efanesoctocog Alfa Beneficial in Severe Hemophilia A – HealthDay

Commentary on Twitter with a video summary

Efanesoctocog alfa is a new class of factor VIII replacement for hemophilia A that has a longer half-life than other factor VIII products, thus allowing once-weekly dosing. New research findings are summarized in a short video. https://t.co/YuXzifUh8m pic.twitter.com/POCAAfeEni

— NEJM (@NEJM) January 27, 2023

Practice Guidance | Anticoagulation in adult patients supported with extracorporeal membrane oxygenation

30 Jan, 2023 | 00:56h | UTC

Anticoagulation in adult patients supported with extracorporeal membrane oxygenation: guidance from the Scientific and Standardization Committees on Perioperative and Critical Care Haemostasis and Thrombosis of the International Society on Thrombosis and Haemostasis – Journal of Thrombosis and Haemostasis

RCT | IV ferric carboxymaltose vs. oral ferrous fumarate in anemic children with inflammatory bowel disease

30 Jan, 2023 | 00:18h | UTC

Ferric carboxymaltose versus ferrous fumarate in anemic children with inflammatory bowel disease: the POPEYE randomized controlled clinical trial – The Journal of Pediatrics

Cohort Study | Incidence and impact of anticoagulation-associated abnormal menstrual bleeding after VTE

27 Jan, 2023 | 12:04h | UTC

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism – Blood

Invited Commentary: The burden of heavy menstrual bleeding – Blood

Commentary on Twitter

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism https://t.co/IEftFzyvRl pic.twitter.com/m09sP14inN

— Blood Journal (@BloodJournal) October 26, 2022

Review | Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT)

26 Jan, 2023 | 12:46h | UTC

Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT) – Blood

RCT | Aspirin noninferior to low-molecular-weight heparin for thromboprophylaxis after a fracture

19 Jan, 2023 | 14:30h | UTC

Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Aspirin as effective as blood thinner injections to prevent deadly complications in patients hospitalized with bone fractures – University of Maryland School of Medicine

Commentary: PREVENT CLOT Supports Aspirin for VTE Prevention in Trauma Fractures – TCTMD

M-A | Optimal timing of perioperative chemical thromboprophylaxis in elective major abdominal surgery

19 Jan, 2023 | 13:52h | UTC

Optimal Timing of Perioperative Chemical Thromboprophylaxis in Elective Major Abdominal Surgery: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)

Review | Management of patients with lower-risk myelodysplastic syndromes

19 Jan, 2023 | 13:47h | UTC

Management of patients with lower-risk myelodysplastic syndromes – Blood Cancer Journal

Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score

18 Jan, 2023 | 14:37h | UTC

Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score – European Heart Journal

See calculator: https://vtepredict.com/

Commentary on Twitter

The effect of extended anticoagulant treatment for individual patients with venous thromboembolism: the results from the VTE-PREDICT risk score! #venous #thromboembolism #anticoagulant #bleeding #score #EHJ #cardiotwitter @ESC_Journals @escardio
https://t.co/u3NHWyB9rv pic.twitter.com/ifOFxaXV1I

— EHJ Editor-in-Chief (@ehj_ed) January 17, 2023