Maternal-fetal Medicine
COVID vaccines safely protect pregnant people: the data are in.
14 Jan, 2022 | 08:43h | UTCCOVID vaccines safely protect pregnant people: the data are in – Nature
Related:
COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Cohort Study: In preterm premature rupture of membranes at 24-31 weeks, antibiotic prophylaxis based on third-generation cephalosporin may be associated with improved perinatal outcomes compared to amoxicillin.
13 Jan, 2022 | 08:10h | UTCAntibiotic prophylaxis in preterm premature rupture of membranes at 24-31 weeks’ gestation: perinatal and 2-year outcomes in the EPIPAGE-2 cohort – BJOG (link to abstract – $ for full-text)
Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.
11 Jan, 2022 | 02:08h | UTCCiprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)
AHA Scientific Statement | Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy.
8 Jan, 2022 | 23:16h | UTCNews Release: High blood pressure treatment in pregnancy is safe, prevents maternal heart risks – American Heart Association
Commentary on Twitter
Have you had a chance to check out the new Scientific Statement From the American Heart Association?!?
Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals, and Pharmacotherapy: A Scientific Statement From the American Heart Associationhttps://t.co/hs6zPwOP2N pic.twitter.com/CUs1jxCP5M
— Hypertension (@HyperAHA) December 20, 2021
NICE Guideline | Ectopic pregnancy and miscarriage: diagnosis and initial management.
13 Dec, 2021 | 09:42h | UTC
NICE Guideline | Inducing labor.
13 Dec, 2021 | 08:55h | UTCInducing labour – National Institute for Health and Care Excellence
Two-year follow up of randomized trial shows delaying umbilical cord clamping saves preterm babies’ lives.
13 Dec, 2021 | 08:46h | UTCNews Release: Two-year follow up shows delaying umbilical cord clamping saves babies’ lives – University of Sydney
Related:
Commentaries on Twitter
https://twitter.com/LancetChildAdol/status/1468733380510449667
https://twitter.com/EBNEO/status/1469959007955787781
Systematic Review: Current practices of management of maternal and congenital Cytomegalovirus infection during pregnancy after a maternal primary infection occurring in first trimester of pregnancy.
7 Dec, 2021 | 08:35h | UTC
Consensus on Practical Management of Parathyroid Disorders in Adults and in Pregnancy.
5 Dec, 2021 | 23:43h | UTC
Randomized Trial: Conventional in vitro fertilization resulted in a cumulative live-birth rate that was noninferior to live-birth rates with the addition of preimplantation genetic testing for aneuploidy.
28 Nov, 2021 | 21:14h | UTCLive Birth with or without Preimplantation Genetic Testing for Aneuploidy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: New research casts fresh doubt on a common procedure that promises to increase the odds of IVF – STAT
Podcast | Obstetrics for the Internist: What to Expect.
16 Nov, 2021 | 08:18h | UTC#305 OB for the Internist: What to Expect – The Curbsiders
Cohort study: In utero exposure to 17α-hydroxyprogesterone caproate linked to increased risk of cancer in offspring.
10 Nov, 2021 | 06:59h | UTCIn utero exposure to 17α-hydroxyprogesterone caproate and risk of cancer in offspring – American Journal of Obstetrics and Gynecology (link to abstract – $ for full-text)
COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.
3 Nov, 2021 | 10:09h | UTCRelated:
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
24 Oct, 2021 | 23:58h | UTCFertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination – The Lancet
Related:
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
New research letter: Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination. Authors analysed pregnancies occurring in four ongoing clinical trials in the UK, Brazil, and South Africa. https://t.co/hDM1olKts9@OxfordVacGroup | #COVID19 #AstraZeneca pic.twitter.com/m5qvWhPcph
— The Lancet (@TheLancet) October 23, 2021
A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.
21 Oct, 2021 | 10:14h | UTCRelated:
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Cohort Study: Hypertensive disorders of pregnancy are associated with a 6-fold or higher increased risk of chronic hypertension in the first years following delivery.
21 Oct, 2021 | 09:51h | UTCEditorial: Impact of hypertensive disorders of pregnancy: lessons from CONCEPTION
Commentary on Twitter
Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study@escardio #EHJ #cardiotwitterhttps://t.co/OnJRP94W6v pic.twitter.com/N3dLNTD5XU
— EHJ Editor-in-Chief (@ehj_ed) October 17, 2021
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
15 Oct, 2021 | 02:41h | UTCCovid-19 treatments and vaccines must be evaluated in pregnancy – The BMJ
Related:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
Inconsistent messaging from authorities, driven by lack of trial data, has increased covid-19 vaccine hesitancy among pregnant women@DrAllyah and colleagues argue that pregnant women should be included in drug and vaccine development from the outsethttps://t.co/P3v1ouk8tQ
— The BMJ (@bmj_latest) October 14, 2021
Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.
15 Oct, 2021 | 02:38h | UTCRelated:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter (thread – click for more)
First dataset I have seen for vaccine efficacy in pregnant persons during #Delta era. Impressive aOR for both severe illness (0.11) and infection positivity in general (0.31)! #GetVaccinatedNow 🤰🏻💉 https://t.co/VhBHyeOWjz
— Lauren Hassen, MD MPH (@ljhassen) October 14, 2021
Review | Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
3 Oct, 2021 | 22:23h | UTC
USPSTF Statement: Start low-dose aspirin after 12 weeks of gestation for women at high risk for preeclampsia.
29 Sep, 2021 | 10:12h | UTCEditorial: Low-Dose Aspirin for the Prevention of Preeclampsia
Commentary: Aspirin Use to Prevent Preeclampsia: USPSTF Recommendation – American College of Cardiology
Author interview: USPSTF Recommendation: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality – JAMA
JAMA Patient Page: Use of Aspirin During Pregnancy to Prevent Preeclampsia
Preliminary randomized trial suggests metformin may prolong gestation in preterm pre-eclampsia.
29 Sep, 2021 | 10:02h | UTCNews release: Diabetes drug may help to prolong preterm pregnancies in women with pre-eclampsia – British Medical Journal
Commentary: Metformin May Prolong Gestation in Women With Preterm Preeclampsia – HealthDay
Commentary on Twitter
https://twitter.com/bmj_latest/status/1441643762896211982
Consensus Statement: Paracetamol use during pregnancy — a call for precautionary action – “Pregnant women should minimize risk by using the lowest effective APAP dose for the shortest possible time”.
26 Sep, 2021 | 22:02h | UTCParacetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology
Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology
Commentaries:
New research cautions about possible risks of acetaminophen use during pregnancy – STAT
Expert reaction to statement on paracetamol use during pregnancy – Science Media Centre
A Common Pain Relief Med Used in Pregnancy Should Be Taken with Caution, Experts Warn – ScienceAlert
Commentary on Twitter
New content online: Paracetamol use during pregnancy — a call for precautionary action https://t.co/FhsB5KdRs0 pic.twitter.com/8BQUUWeTbN
— Nature Reviews Endocrinology (@NatureRevEndo) September 23, 2021
Less common bacterial, fungal and viral infections: review of management in the pregnant patient.
26 Sep, 2021 | 21:38h | UTC
Systematic review: Instruments for assisted vaginal birth.
26 Sep, 2021 | 21:35h | UTCInstruments for assisted vaginal birth – Cochrane Library
Summary: Instruments for assisted vaginal birth – Cochrane Library
Large, multinational cohort suggests ondansetron use in pregnancy does not increase the risk for adverse fetal outcomes.
24 Sep, 2021 | 08:57h | UTCEditorial: Providing Data to Empower Pregnant Patients to Make Evidence-Based Choices
Commentary on Twitter
This cohort study found there was no association between ondansetron exposure during pregnancy and increased risk of fetal death, spontaneous abortion, stillbirth, or major congenital malformations compared with exposure to other antiemetic drugs. https://t.co/hDXr72Ga01
— JAMA Network Open (@JAMANetworkOpen) April 23, 2021