Maternal-fetal Medicine
Progesterone, cervical cerclage or cervical pessary to prevent preterm birth: a decision-making analysis of international guidelines.
26 Apr, 2022 | 07:30h | UTC
Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.
25 Apr, 2022 | 00:59h | UTCCommentaries:
COVID vaccine in early pregnancy not tied to birth defects – CIDRAP
No Sign That COVID Vaccine in Pregnancy Raises Birth Defect Risk – HealthDay
UK drug regulator advises patients and doctors against the use of Pregabalin during pregnancy due to a possible increased risk of congenital malformations.
22 Apr, 2022 | 09:31h | UTCSee also: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Source: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Commentary on Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
Vitamin D supplements in pregnancy: what’s the latest evidence?
21 Apr, 2022 | 09:58h | UTCVitamin D supplements in pregnancy: what’s the latest evidence? – Evidently Cochrane Blog
Original Study: Vitamin D supplementation for women during pregnancy – Cochrane Library
FDA warns of risks associated with non-invasive prenatal screening tests – inappropriate interpretation of results may lead to potentially improper medical decisions.
20 Apr, 2022 | 09:52h | UTC
M-A: Invasive group A streptococcal disease in pregnant women and young children.
20 Apr, 2022 | 09:05h | UTCInvited Commentary: Recognising group A streptococcal disease in pregnancy – The Lancet Infectious Diseases (free registration required)
Review: Preterm premature rupture of membranes – inpatient versus outpatient management.
20 Apr, 2022 | 09:06h | UTC
Systematic Review: Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes.
20 Apr, 2022 | 09:03h | UTC
Discharge preparation and readiness after birth: a scoping review of global policies, guidelines and literature.
14 Apr, 2022 | 08:07h | UTCRelated:
WHO recommendations on maternal and newborn care for a positive postnatal experience.
Putting positive experiences at the center of postnatal care.
M-A: Adverse perinatal outcomes associated with protease inhibitor-based antiretroviral therapy in pregnant women living with HIV.
13 Apr, 2022 | 10:18h | UTCNews Release: Protease inhibitors safer than thought for pregnant women with HIV – University of Oxford
CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study.
11 Apr, 2022 | 01:40h | UTC
Putting positive experiences at the center of postnatal care.
8 Apr, 2022 | 10:34h | UTCPutting positive experiences at the centre of postnatal care – Evidently Cochrane Blog
Original Guideline: WHO recommendations on maternal and newborn care for a positive postnatal experience.
#ACC22 – RCT: Treatment for mild chronic hypertension during pregnancy is associated with better pregnancy outcomes than a strategy of reserving treatment only for severe hypertension.
4 Apr, 2022 | 01:34h | UTCTreatment for Mild Chronic Hypertension during Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Treating chronic hypertension in early pregnancy benefits parents, babies – NIH News Releases
CHAP: Better Blood Pressure Control, Better Pregnancy Outcomes – TCTMD
Commentary on Twitter
In pregnant women with mild chronic hypertension, targeting a blood pressure of < 140/90 mm Hg was associated with better pregnancy outcomes than a strategy of reserving treatment only for severe hypertension. #ACC22 https://t.co/fDrqa8uQiO pic.twitter.com/9KvogjnKcc
— NEJM (@NEJM) April 2, 2022
M-A: Global estimates of diabetic retinopathy prevalence and progression in pregnant women with preexisting diabetes.
4 Apr, 2022 | 00:42h | UTCGlobal Estimates of Diabetic Retinopathy Prevalence and Progression in Pregnant Women With Preexisting Diabetes: A Systematic Review and Meta-analysis – JAMA Ophthalmology (free for a limited period)
Invited Commentary: Diabetic Retinopathy in Pregnancy – JAMA Ophthalmology (free for a limited period)
Commentary on Twitter
In this study, higher #diabeticretinopathy (DR) prevalences were found in pregnant women with pre-existing #diabetes compared w non-pregnant women. Women with T2D compared w T1D were not noted to have a different risk of DR progression during pregnancy. https://t.co/lfTi9kIBTj
— JAMAOphthalmology (@JAMAOphth) April 1, 2022
Study finds mother-to-child transmission of COVID-19 infection is possible but rare.
1 Apr, 2022 | 09:52h | UTCNews Release: Mother to child transmission of COVID-19 infection, possible but rare, study finds – University of Birmingham
Original Study: SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis – The BMJ
Editorial: Transmission of SARS-CoV-2 from mother to baby is rare
Commentary on Twitter
Mother-to-child transmission of SARS-CoV-2 has been controversial. Our living systematic review & meta-analysis has just been published in BMJ. Transmission has been confirmed, although it is rare, & is more likely when the maternal COVID-19 is severe.https://t.co/Z15kFIk6Zp
— Asma Khalil (@ProfAsmaKhalil) March 19, 2022
WHO recommendations on maternal and newborn care for a positive postnatal experience.
31 Mar, 2022 | 08:47h | UTCNews Release: WHO urges quality care for women and newborns in critical first weeks after childbirth – World Health Organization
Commentary: Postnatal care: WHO highlights urgency of physical and mental support – The BMJ
What to expect when women with axial spondyloarthritis are expecting: Prevalence of complications of pregnancies in women with axial spondyloarthritis.
30 Mar, 2022 | 10:01h | UTC
Commentary on Twitter
ICYMI: Among 98 women with axSpA, there were 335 pregnancies & 279 live births – 52% uncomplicated and 48% complicated (13%) multiple complications. axSpA had more Preterm birth (13 vs 5%), pre-eclampsia (7 vs 3%), Low birth Wt (8 vs 3%) https://t.co/1oFBKSUzzy pic.twitter.com/oLbYis81Y9
— Dr. John Cush (@RheumNow) March 28, 2022
AI estimation of gestational age from blind ultrasound sweeps in low-resource settings.
30 Mar, 2022 | 09:53h | UTC
Commentary on Twitter
Pregnancies were dated in a low-resource setting using a mobile phone and a low-cost ultrasound probe to acquire sweeps of the gravid abdomen by untrained personnel. An AI program yielded dates that were similar to those obtained in higher resource sites. https://t.co/Cc3NTTDzfg pic.twitter.com/cEug9kMXQF
— NEJM Evidence (@NEJMEvidence) March 28, 2022
Cohort Study: Prenatal occupational disinfectant exposure linked to increased risk of childhood allergies.
30 Mar, 2022 | 08:48h | UTCCommentary: Disinfectant use by pregnant women may increase risk for asthma and eczema in children – BMJ/News Medical
Commentary on Twitter
Disinfectant use during pregnancy linked to childhood asthma and eczema, suggests @OEM_BMJ research https://t.co/90JYoTFHpo pic.twitter.com/zlqouZWQSM
— BMJ (@bmj_company) March 29, 2022
Cohort Study: Preconception paternal use of metformin linked to increased risk of congenital problems in offspring.
29 Mar, 2022 | 10:04h | UTCPreconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Association of antipsychotic drug exposure in pregnancy with risk of neurodevelopmental disorders: a national birth cohort study.
29 Mar, 2022 | 08:46h | UTCAssociation of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study – JAMA Internal Medicine (free for a limited period)
Retrospective Cohort: A population-based study in Sweden and Norway did not find an increased risk of pregnancy complications after COVID-19 vaccination.
28 Mar, 2022 | 09:51h | UTCAssociation of SARS-CoV-2 Vaccination During Pregnancy With Pregnancy Outcomes – JAMA
See also: Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes – JAMA
Editorial: COVID-19 mRNA Vaccines During Pregnancy: New Evidence to Help Address Vaccine Hesitancy – JAMA
News Release: No increase in pregnancy complications after COVID-19 vaccination – Karolinska Institutet
FIGO recommendations on the management of postpartum hemorrhage 2022.
24 Mar, 2022 | 08:38h | UTCFIGO recommendations on the management of postpartum hemorrhage 2022 – Gynecology & Obstetrics
Related:
[Abstract Only] Meta-Analysis: Uterine Balloon Tamponade for the Treatment of Postpartum Hemorrhage
Consensus Statement: Prevention and Treatment of Postpartum Hemorrhage
WHO Guideline: Uterotonics for the Prevention of Postpartum Hemorrhage
Cohort Study: Perinatal complications in individuals in California with or without SARS-CoV-2 infection during pregnancy.
23 Mar, 2022 | 10:33h | UTCNews Release: Coronavirus may double severe complications in pregnancy – Kaiser Permanente
Commentary: COVID-19 in pregnancy tied to poor maternal outcomes, preterm birth, fetal death – CIDRAP
Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.
22 Mar, 2022 | 09:42h | UTCWhole-genome risk prediction of common diseases in human preimplantation embryos – Nature Medicine
Invited Commentaries:
Polygenic embryo testing: understated ethics, unclear utility – Nature Medicine
The uncertain science of preimplantation and prenatal genetic testing – Nature Medicine
Commentary on Twitter (thread – click for more)
Preimplantation genetic testing of human embryos is a rapidly advancing field, but scientists and ethicists are calling for caution.
We present 3 articles highlighting new research and expert commentary on this controversial topic.
THREAD ?— Nature Medicine (@NatureMedicine) March 21, 2022